haloperidol-2663 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the haloperidol-2663 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM5 acyl-CoA synthetase medium-chain family member 5
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGMAT agmatine ureohydrolase (agmatinase)
AIM2 absent in melanoma 2
ANKH ANKH inorganic pyrophosphate transport regulator
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BLZF1 basic leucine zipper nuclear factor 1
BMP7 bone morphogenetic protein 7
C17ORF59 chromosome 17 open reading frame 59
C4ORF19 chromosome 4 open reading frame 19
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC64 coiled-coil domain containing 64
CCL7 chemokine (C-C motif) ligand 7
CCSER2 coiled-coil serine-rich protein 2
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDC42 cell division cycle 42
CDY1 chromodomain protein, Y-linked, 1
CHMP6 charged multivesicular body protein 6
CHRND cholinergic receptor, nicotinic, delta (muscle)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
COL17A1 collagen, type XVII, alpha 1
CRTC1 CREB regulated transcription coactivator 1
DCAF17 DDB1 and CUL4 associated factor 17
DCAF4 DDB1 and CUL4 associated factor 4
DCLK2 doublecortin-like kinase 2
DGKE diacylglycerol kinase, epsilon 64kDa
DGKQ diacylglycerol kinase, theta 110kDa
DIAPH2 diaphanous-related formin 2
EDRF1 erythroid differentiation regulatory factor 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAIM Fas apoptotic inhibitory molecule
FGL2 fibrinogen-like 2
FNTB farnesyltransferase, CAAX box, beta
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GK3P glycerol kinase 3 pseudogene
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HAP1 huntingtin-associated protein 1
HCRTR2 hypocretin (orexin) receptor 2
HEMK1 HemK methyltransferase family member 1
HIPK3 homeodomain interacting protein kinase 3
HNMT histamine N-methyltransferase
HOXD1 homeobox D1
IDS iduronate 2-sulfatase
IFI6 interferon, alpha-inducible protein 6
JAK3 Janus kinase 3
KCTD20 potassium channel tetramerization domain containing 20
KIF1C kinesin family member 1C
LHX3 LIM homeobox 3
LMX1B LIM homeobox transcription factor 1, beta
LRP1 low density lipoprotein receptor-related protein 1
MCTP2 multiple C2 domains, transmembrane 2
MTUS1 microtubule associated tumor suppressor 1
N4BP2L2 NEDD4 binding protein 2-like 2
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NMBR neuromedin B receptor
NQO1 NAD(P)H dehydrogenase, quinone 1
NRP1 neuropilin 1
NRP2 neuropilin 2
NUP50 nucleoporin 50kDa
PAPPA2 pappalysin 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PDLIM5 PDZ and LIM domain 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHTF2 putative homeodomain transcription factor 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRO2964 uncharacterized protein PRO2964
PROL1 proline rich, lacrimal 1
QSER1 glutamine and serine rich 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RANBP1 RAN binding protein 1
RHBDD3 rhomboid domain containing 3
SCG5 secretogranin V
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMAD5 SMAD family member 5
SNX13 sorting nexin 13
SOX15 SRY (sex determining region Y)-box 15
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STX7 syntaxin 7
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TEX40 testis expressed 40
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
USP53 ubiquitin specific peptidase 53
USP6NL USP6 N-terminal like
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VWA8 von Willebrand factor A domain containing 8
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC14 zinc finger, CCHC domain containing 14
ZER1 zyg-11 related, cell cycle regulator
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AEN apoptosis enhancing nuclease
AK1 adenylate kinase 1
ANKRD40 ankyrin repeat domain 40
ARMCX4 armadillo repeat containing, X-linked 4
BNC2 basonuclin 2
BTF3P12 basic transcription factor 3 pseudogene 12
C7ORF69 chromosome 7 open reading frame 69
CABP2 calcium binding protein 2
CCDC106 coiled-coil domain containing 106
CD3D CD3d molecule, delta (CD3-TCR complex)
CDON cell adhesion associated, oncogene regulated
CGA glycoprotein hormones, alpha polypeptide
CLCF1 cardiotrophin-like cytokine factor 1
CLEC2D C-type lectin domain family 2, member D
CNN1 calponin 1, basic, smooth muscle
CPTP ceramide-1-phosphate transfer protein
CXCL2 chemokine (C-X-C motif) ligand 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DOC2A double C2-like domains, alpha
DOCK5 dedicator of cytokinesis 5
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
ENO3 enolase 3 (beta, muscle)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHB6 EPH receptor B6
FAM102A family with sequence similarity 102, member A
FAM127B family with sequence similarity 127, member B
FBXL6 F-box and leucine-rich repeat protein 6
FKBPL FK506 binding protein like
FZD4 frizzled class receptor 4
GATA6 GATA binding protein 6
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSDMD gasdermin D
GSTZ1 glutathione S-transferase zeta 1
HAMP hepcidin antimicrobial peptide
HIST1H2AM histone cluster 1, H2am
HPR haptoglobin-related protein
HPSE heparanase
IFT81 intraflagellar transport 81
JAM3 junctional adhesion molecule 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT81 keratin 81, type II
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIMD2 LIM domain containing 2
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LOC729164 hCG1732469
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
METTL16 methyltransferase like 16
MRPS18C mitochondrial ribosomal protein S18C
MTHFSD methenyltetrahydrofolate synthetase domain containing
MXD3 MAX dimerization protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NLGN1 neuroligin 1
NOL6 nucleolar protein 6 (RNA-associated)
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PCBP4 poly(rC) binding protein 4
PMP22 peripheral myelin protein 22
PRDM12 PR domain containing 12
PRF1 perforin 1 (pore forming protein)
PRR7 proline rich 7 (synaptic)
PYGB phosphorylase, glycogen; brain
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIN2 Ras and Rab interactor 2
RNF123 ring finger protein 123
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL13P5 ribosomal protein L13 pseudogene 5
SETD8 SET domain containing (lysine methyltransferase) 8
SETMAR SET domain and mariner transposase fusion gene
SIX3 SIX homeobox 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SNX16 sorting nexin 16
STEAP4 STEAP family member 4
SYNPO2L synaptopodin 2-like
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM7SF2 transmembrane 7 superfamily member 2
TMEM212 transmembrane protein 212
TMEM254 transmembrane protein 254
TOM1 target of myb1 (chicken)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
UNC13A unc-13 homolog A (C. elegans)
UPK3A uroplakin 3A
USP32 ubiquitin specific peptidase 32
VEGFC vascular endothelial growth factor C
ZBTB25 zinc finger and BTB domain containing 25
ZNF219 zinc finger protein 219
ZNF276 zinc finger protein 276
ZNF747 zinc finger protein 747