hair follicle outer root sheath Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description It surrounds the hair follicle like a sleeve all the way to the bulb. The outer root sheath is essentially a stratified epithelium that is contiguous with the epidermis. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003969)
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Genes

236 proteins co-occuring with the tissue hair follicle outer root sheath in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
KRT15 keratin 15, type I 2.75124
CLEC2A C-type lectin domain family 2, member A 1.80615
CD200 CD200 molecule 1.69351
KRT14 keratin 14, type I 1.62856
FLG filaggrin 1.60962
IVL involucrin 1.59028
KRT16 keratin 16, type I 1.5015
CD34 CD34 molecule 1.34814
TCHH trichohyalin 1.28771
NES nestin 1.25637
FGF5 fibroblast growth factor 5 1.25145
KRT27 keratin 27, type I 1.23405
SCEL sciellin 1.23138
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.19001
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 1.16604
DSG1 desmoglein 1 1.15894
DSG3 desmoglein 3 1.14609
KRTDAP keratinocyte differentiation-associated protein 1.14387
HRNR hornerin 1.13634
LOR loricrin 1.12881
LHX2 LIM homeobox 2 1.10668
KRT1 keratin 1, type II 1.07971
BNC1 basonuclin 1 1.07574
KRT6A keratin 6A, type II 1.05457
SH3YL1 SH3 and SYLF domain containing 1 1.01725
GLI1 GLI family zinc finger 1 1.01549
EGFL6 EGF-like-domain, multiple 6 1.00676
KRT8 keratin 8, type II 0.987597
PHAX phosphorylated adaptor for RNA export 0.975015
KRT10 keratin 10, type I 0.966793
KRT38 keratin 38, type I 0.958585
NPNT nephronectin 0.954271
KRT17 keratin 17, type I 0.949531
PKP1 plakophilin 1 0.939206
HOXC12 homeobox C12 0.930193
TYRP1 tyrosinase-related protein 1 0.896045
PKP3 plakophilin 3 0.894346
TGM1 transglutaminase 1 0.880358
KRT81 keratin 81, type II 0.877397
TGFB2 transforming growth factor, beta 2 0.867686
HOXC13 homeobox C13 0.865999
KRT75 keratin 75, type II 0.844545
KRT35 keratin 35, type I 0.844126
SOX9 SRY (sex determining region Y)-box 9 0.834061
NGFR nerve growth factor receptor 0.810638
PLET1 placenta expressed transcript 1 0.802293
MVB12A multivesicular body subunit 12A 0.774419
KRT86 keratin 86, type II 0.768612
KRT20 keratin 20, type I 0.761984
CYTIP cytohesin 1 interacting protein 0.757845
LEF1 lymphoid enhancer-binding factor 1 0.749992
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.734735
KRT5 keratin 5, type II 0.732677
KRT19 keratin 19, type I 0.726097
DSC3 desmocollin 3 0.726097
NOTCH1 notch 1 0.722809
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.722809
AR androgen receptor 0.71583
GLI2 GLI family zinc finger 2 0.713779
FOXE1 forkhead box E1 0.70968
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.70886
S100A7 S100 calcium binding protein A7 0.705583
TRPS1 trichorhinophalangeal syndrome I 0.702308
KRT7 keratin 7, type II 0.689634
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.683511
MED1 mediator complex subunit 1 0.665182
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 0.664775
PLEKHM3 pleckstrin homology domain containing, family M, member 3 0.662336
SHH sonic hedgehog 0.6534
WNT10B wingless-type MMTV integration site family, member 10B 0.650154
ITGA6 integrin, alpha 6 0.646505
TGFB1 transforming growth factor, beta 1 0.645695
S100A3 S100 calcium binding protein A3 0.629101
TYR tyrosinase 0.625465
FGF7 fibroblast growth factor 7 0.622235
S100A6 S100 calcium binding protein A6 0.619007
DSC2 desmocollin 2 0.603697
KRT12 keratin 12, type I 0.600077
MITF microphthalmia-associated transcription factor 0.59405
ODC1 ornithine decarboxylase 1 0.591641
BARX2 BARX homeobox 2 0.588832
PDLIM2 PDZ and LIM domain 2 (mystique) 0.581618
DSG2 desmoglein 2 0.570021
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.566828
FST follistatin 0.565232
PRLR prolactin receptor 0.556467
SDC1 syndecan 1 0.55408
KRT31 keratin 31, type I 0.548914
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.548914
EDARADD EDAR-associated death domain 0.543756
HAUS3 HAUS augmin-like complex, subunit 3 0.53267
POFUT1 protein O-fucosyltransferase 1 0.524377
HMGN1 high mobility group nucleosome binding domain 1 0.523194
FGF18 fibroblast growth factor 18 0.5228
PTCH1 patched 1 0.511778
PCNA proliferating cell nuclear antigen 0.510599
KRT4 keratin 4, type II 0.505887
FGFR2 fibroblast growth factor receptor 2 0.50079
PRKCH protein kinase C, eta 0.49844
KRTAP11-1 keratin associated protein 11-1 0.496092
BCL2 B-cell CLL/lymphoma 2 0.491791
CRABP2 cellular retinoic acid binding protein 2 0.489057
SMO smoothened, frizzled class receptor 0.482817
RNASE7 ribonuclease, RNase A family, 7 0.481648
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.477756
ITSN1 intersectin 1 (SH3 domain protein) 0.475034
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.472315
FGF13 fibroblast growth factor 13 0.468436
KRT3 keratin 3, type II 0.457987
HOXB4 homeobox B4 0.454898
INSC inscuteable homolog (Drosophila) 0.448731
ILK integrin-linked kinase 0.445268
AMIGO2 adhesion molecule with Ig-like domain 2 0.442194
NRG3 neuregulin 3 0.442194
DEFB1 defensin, beta 1 0.441042
TGFB3 transforming growth factor, beta 3 0.439123
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.434523
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 0.43414
PDPN podoplanin 0.428783
FGF10 fibroblast growth factor 10 0.428401
LGALS1 lectin, galactoside-binding, soluble, 1 0.424963
FN1 fibronectin 1 0.419242
CTSV cathepsin V 0.414673
FMO3 flavin containing monooxygenase 3 0.413912
KITLG KIT ligand 0.411251
HMGN2 high mobility group nucleosomal binding domain 2 0.408592
TFRC transferrin receptor 0.405176
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.405176
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.404039
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.401386
LGALS3 lectin, galactoside-binding, soluble, 3 0.399114
DCT dopachrome tautomerase 0.398735
BCAP31 B-cell receptor-associated protein 31 0.396087
DSC1 desmocollin 1 0.393064
WNT16 wingless-type MMTV integration site family, member 16 0.382884
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.381755
FZD3 frizzled class receptor 3 0.377245
VCAN versican 0.367129
SPRY4 sprouty homolog 4 (Drosophila) 0.363766
DEFB4A defensin, beta 4A 0.351856
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.34963
EFNA3 ephrin-A3 0.34963
SIN3A SIN3 transcription regulator family member A 0.345928
JAG2 jagged 2 0.341495
FGF1 fibroblast growth factor 1 (acidic) 0.340757
TPRG1L tumor protein p63 regulated 1-like 0.332294
IGF1 insulin-like growth factor 1 (somatomedin C) 0.327164
PKP2 plakophilin 2 0.326432
LGALS7B lectin, galactoside-binding, soluble, 7B 0.326432
GLB1 galactosidase, beta 1 0.322779
FZD5 frizzled class receptor 5 0.320227
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.319134
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.316588
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.308612
EGFR epidermal growth factor receptor 0.308612
LTBP3 latent transforming growth factor beta binding protein 3 0.308251
GJA1 gap junction protein, alpha 1, 43kDa 0.307528
LDB1 LIM domain binding 1 0.303198
JUP junction plakoglobin 0.300679
LTBP2 latent transforming growth factor beta binding protein 2 0.296372
S100A2 S100 calcium binding protein A2 0.295297
EHF ets homologous factor 0.290652
GALR3 galanin receptor 3 0.290295
CSPG4 chondroitin sulfate proteoglycan 4 0.287092
HOXA4 homeobox A4 0.283545
WNT7B wingless-type MMTV integration site family, member 7B 0.280717
GJB3 gap junction protein, beta 3, 31kDa 0.278955
CALB2 calbindin 2 0.278603
WIF1 WNT inhibitory factor 1 0.276963
DLG3 discs, large homolog 3 (Drosophila) 0.276846
KRT83 keratin 83, type II 0.276495
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.276145
CD24 CD24 molecule 0.272765
DVL2 dishevelled segment polarity protein 2 0.272649
BCAM basal cell adhesion molecule (Lutheran blood group) 0.270909
FGF6 fibroblast growth factor 6 0.269174
ADSL adenylosuccinate lyase 0.266757
WNT7A wingless-type MMTV integration site family, member 7A 0.264696
ECM1 extracellular matrix protein 1 0.261964
HDAC2 histone deacetylase 2 0.261284
IL1R2 interleukin 1 receptor, type II 0.259591
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.257572
RARG retinoic acid receptor, gamma 0.256568
BAK1 BCL2-antagonist/killer 1 0.255234
BMP5 bone morphogenetic protein 5 0.254902
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.253248
HOPX HOP homeobox 0.251606
MSX2 msh homeobox 2 0.24676
DLX3 distal-less homeobox 3 0.246442
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.243605
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.242054
PSIP1 PC4 and SFRS1 interacting protein 1 0.238706
GAS1 growth arrest-specific 1 0.238706
FGFR1 fibroblast growth factor receptor 1 0.235457
LONP1 lon peptidase 1, mitochondrial 0.234016
CCL27 chemokine (C-C motif) ligand 27 0.230382
NTF3 neurotrophin 3 0.229568
FZD1 frizzled class receptor 1 0.229568
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.228764
HRH4 histamine receptor H4 0.2259
DIO2 deiodinase, iodothyronine, type II 0.224398
TP53 tumor protein p53 0.221989
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.221989
NGF nerve growth factor (beta polypeptide) 0.221291
BIN1 bridging integrator 1 0.219707
SEPT4 septin 4 0.218186
TGFBR1 transforming growth factor, beta receptor 1 0.217974
S100A4 S100 calcium binding protein A4 0.21673
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.216193
PEG10 paternally expressed 10 0.215341
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.215018
TYRO3 TYRO3 protein tyrosine kinase 0.214202
NANOG Nanog homeobox 0.21247
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.211791
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.20191
MCAM melanoma cell adhesion molecule 0.201606
NID1 nidogen 1 0.197808
FBN1 fibrillin 1 0.197526
RSPO1 R-spondin 1 0.193129
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.192716
ARHGAP1 Rho GTPase activating protein 1 0.192153
WNT3A wingless-type MMTV integration site family, member 3A 0.191705
FLCN folliculin 0.191555
LRP6 low density lipoprotein receptor-related protein 6 0.18918
SOX2 SRY (sex determining region Y)-box 2 0.187921
TMSB4X thymosin beta 4, X-linked 0.185743
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.185664
CD8B CD8b molecule 0.184867
CADM1 cell adhesion molecule 1 0.184146
RUNX1 runt-related transcription factor 1 0.183548
JAG1 jagged 1 0.182414
CLDN1 claudin 1 0.181505
KLF4 Kruppel-like factor 4 (gut) 0.181282
CLDN7 claudin 7 0.180997
HDAC1 histone deacetylase 1 0.180822
ADAM17 ADAM metallopeptidase domain 17 0.179376