guanadrel-3438 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the guanadrel-3438 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
BST2 bone marrow stromal cell antigen 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN15 calpain 15
CCDC121 coiled-coil domain containing 121
CCNO cyclin O
CLIP4 CAP-GLY domain containing linker protein family, member 4
CREBZF CREB/ATF bZIP transcription factor
CTAGE5 CTAGE family, member 5
DBR1 debranching RNA lariats 1
DNALI1 dynein, axonemal, light intermediate chain 1
DOC2A double C2-like domains, alpha
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNA dystrobrevin, alpha
DVL2 dishevelled segment polarity protein 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECE1 endothelin converting enzyme 1
FAM134B family with sequence similarity 134, member B
FSTL1 follistatin-like 1
GJA9 gap junction protein, alpha 9, 59kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPATCH3 G patch domain containing 3
GPSM3 G-protein signaling modulator 3
GSTP1 glutathione S-transferase pi 1
H2AFV H2A histone family, member V
HLA-C major histocompatibility complex, class I, C
HSPA1L heat shock 70kDa protein 1-like
INCENP inner centromere protein antigens 135/155kDa
ING1 inhibitor of growth family, member 1
IQSEC2 IQ motif and Sec7 domain 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM8 lysine (K)-specific demethylase 8
KITLG KIT ligand
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEPR leptin receptor
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MINK1 misshapen-like kinase 1
MOCS1 molybdenum cofactor synthesis 1
MSL3 male-specific lethal 3 homolog (Drosophila)
MSMB microseminoprotein, beta-
NMT1 N-myristoyltransferase 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUP62CL nucleoporin 62kDa C-terminal like
NXPH4 neurexophilin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PALM paralemmin
PGAP3 post-GPI attachment to proteins 3
PHF20 PHD finger protein 20
PLXNB1 plexin B1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLM polymerase (DNA directed), mu
PPAP2B phosphatidic acid phosphatase type 2B
PRDM16 PR domain containing 16
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB35 RAB35, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RBM8A RNA binding motif protein 8A
RPL10L ribosomal protein L10-like
RPL26 ribosomal protein L26
SAMD4A sterile alpha motif domain containing 4A
SARM1 sterile alpha and TIR motif containing 1
SCG2 secretogranin II
SCN1B sodium channel, voltage gated, type I beta subunit
SLC35E2 solute carrier family 35, member E2
SLC46A3 solute carrier family 46, member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOCS6 suppressor of cytokine signaling 6
SPHK2 sphingosine kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STYK1 serine/threonine/tyrosine kinase 1
TAPBP TAP binding protein (tapasin)
TBC1D17 TBC1 domain family, member 17
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM242 transmembrane protein 242
TMPRSS4 transmembrane protease, serine 4
TOR4A torsin family 4, member A
TPP1 tripeptidyl peptidase I
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRD T cell receptor delta locus
UNC119 unc-119 homolog (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WDR55 WD repeat domain 55
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF227 zinc finger protein 227
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARSB arylsulfatase B
ATAD3A ATPase family, AAA domain containing 3A
ATAD5 ATPase family, AAA domain containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
C16ORF59 chromosome 16 open reading frame 59
C4ORF29 chromosome 4 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CGREF1 cell growth regulator with EF-hand domain 1
CHML choroideremia-like (Rab escort protein 2)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COL9A2 collagen, type IX, alpha 2
COPS7B COP9 signalosome subunit 7B
CRABP1 cellular retinoic acid binding protein 1
CRLF1 cytokine receptor-like factor 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF13 DDB1 and CUL4 associated factor 13
DGKE diacylglycerol kinase, epsilon 64kDa
DNAL4 dynein, axonemal, light chain 4
EPPK1 epiplakin 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FAM193B family with sequence similarity 193, member B
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
GAN gigaxonin
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GID4 GID complex subunit 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0556 KIAA0556
LAMB2 laminin, beta 2 (laminin S)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC257152 uncharacterized LOC257152
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC8E leucine rich repeat containing 8 family, member E
LZTFL1 leucine zipper transcription factor-like 1
MNX1 motor neuron and pancreas homeobox 1
OXTR oxytocin receptor
PCDHB3 protocadherin beta 3
PER3 period circadian clock 3
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD2 phospholipase D2
PRPH peripherin
PRR14L proline rich 14-like
PTDSS2 phosphatidylserine synthase 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RIN2 Ras and Rab interactor 2
RP2 retinitis pigmentosa 2 (X-linked recessive)
SFMBT1 Scm-like with four mbt domains 1
SH2B3 SH2B adaptor protein 3
SHARPIN SHANK-associated RH domain interactor
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SP140L SP140 nuclear body protein-like
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TCTN1 tectonic family member 1
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIPRL TOR signaling pathway regulator
TMEM104 transmembrane protein 104
TMEM53 transmembrane protein 53
TNS2 tensin 2
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC23 tetratricopeptide repeat domain 23
TTC4 tetratricopeptide repeat domain 4
TUBA4A tubulin, alpha 4a
TWF2 twinfilin actin binding protein 2
USP20 ubiquitin specific peptidase 20
WDR4 WD repeat domain 4
WDR76 WD repeat domain 76
WWC2 WW and C2 domain containing 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF282 zinc finger protein 282
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF652 zinc finger protein 652
ZNF672 zinc finger protein 672
ZNF721 zinc finger protein 721
ZNF767P zinc finger family member 767, pseudogene
ZNF813 zinc finger protein 813
ZNRD1-AS1 ZNRD1 antisense RNA 1