glioma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A cell type cancer that has_material_basis_in glial cells and is located_in brain or located_in spine. (Human Disease Ontology, DOID_3070)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0009733
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Genes

99 genes associated with the glioma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
TERT telomerase reverse transcriptase 1.84688
CDKN2B-AS1 CDKN2B antisense RNA 1 1.76413
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.71325
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1.58272
RTEL1 regulator of telomere elongation helicase 1 1.53903
PHLDB1 pleckstrin homology-like domain, family B, member 1 1.45654
KIF26B kinesin family member 26B 1.26931
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.25729
SMYD3 SET and MYND domain containing 3 1.19392
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1.17134
EGFR epidermal growth factor receptor 1.16661
DBT dihydrolipoamide branched chain transacylase E2 1.13911
TRAF5 TNF receptor-associated factor 5 1.09432
ACOT11 acyl-CoA thioesterase 11 1.05955
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.99698
MIR205HG MIR205 host gene 0.971944
KAZN kazrin, periplakin interacting protein 0.923916
CCDC23 coiled-coil domain containing 23 0.846368
RLF rearranged L-myc fusion 0.834343
PLD5 phospholipase D family, member 5 0.778318
HIAT1 hippocampus abundant transcript 1 0.752335
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 0.743226
SASS6 spindle assembly 6 homolog (C. elegans) 0.722116
OR2M7 olfactory receptor, family 2, subfamily M, member 7 0.647116
LEPR leptin receptor 0.639858
LRP1B low density lipoprotein receptor-related protein 1B 0.635284
PARD3B par-3 family cell polarity regulator beta 0.630903
ANKAR ankyrin and armadillo repeat containing 0.622665
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.592807
VWA3B von Willebrand factor A domain containing 3B 0.592807
SRBD1 S1 RNA binding domain 1 0.588321
SPP2 secreted phosphoprotein 2, 24kDa 0.581861
MGMT O-6-methylguanine-DNA methyltransferase 0.407127
SSBP2 single-stranded DNA binding protein 2 0.376528
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.360941
USP10 ubiquitin specific peptidase 10 0.360941
KAT2B K(lysine) acetyltransferase 2B 0.359537
LINC00189 long intergenic non-protein coding RNA 189 0.358325
DCC DCC netrin 1 receptor 0.357225
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.356379
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.3556
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.355233
OGFRL1 opioid growth factor receptor-like 1 0.353969
FRMD8 FERM domain containing 8 0.353812
PCSK6 proprotein convertase subtilisin/kexin type 6 0.352041
IQSEC3 IQ motif and Sec7 domain 3 0.350942
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.350771
MAN1B1 mannosidase, alpha, class 1B, member 1 0.349291
LOC146513 uncharacterized LOC146513 0.349025
SHROOM3 shroom family member 3 0.349025
ZMYND15 zinc finger, MYND-type containing 15 0.348416
TTYH1 tweety family member 1 0.347338
LOC100507195 uncharacterized LOC100507195 0.347162
BTNL2 butyrophilin-like 2 0.345771
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 0.344998
DOCK1 dedicator of cytokinesis 1 0.344478
CLIP3 CAP-GLY domain containing linker protein 3 0.343888
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.343605
SCARB1 scavenger receptor class B, member 1 0.342223
PTPRO protein tyrosine phosphatase, receptor type, O 0.341356
PAQR5 progestin and adipoQ receptor family member V 0.3413
GPA33 glycoprotein A33 (transmembrane) 0.341273
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.340893
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 0.340603
SP100 SP100 nuclear antigen 0.340448
GTSF1 gametocyte specific factor 1 0.33968
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.339513
FAM13A family with sequence similarity 13, member A 0.339257
DPH6 diphthamine biosynthesis 6 0.339119
MRPL23 mitochondrial ribosomal protein L23 0.338434
FOXP1 forkhead box P1 0.338434
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.337931
PPA2 pyrophosphatase (inorganic) 2 0.336747
DLG2 discs, large homolog 2 (Drosophila) 0.335234
PARK2 parkin RBR E3 ubiquitin protein ligase 0.33509
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.335059
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.33498
PITPNM3 PITPNM family member 3 0.334933
DOCK5 dedicator of cytokinesis 5 0.334695
CDH23 cadherin-related 23 0.334473
DGKI diacylglycerol kinase, iota 0.334088
TMEM222 transmembrane protein 222 0.334022
CEP128 centrosomal protein 128kDa 0.333763
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.333199
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.333137
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.332971
AADACL3 arylacetamide deacetylase-like 3 0.332851
ARID1A AT rich interactive domain 1A (SWI-like) 0.332297
INSC inscuteable homolog (Drosophila) 0.332127
LOXHD1 lipoxygenase homology domains 1 0.331891
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.331863
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.331686
SLIT3 slit homolog 3 (Drosophila) 0.331591
MROH2A maestro heat-like repeat family member 2A 0.331537
RAI1 retinoic acid induced 1 0.331484
MTUS1 microtubule associated tumor suppressor 1 0.331272
ADGRB3 adhesion G protein-coupled receptor B3 0.331259
SASH1 SAM and SH3 domain containing 1 0.330987
ONECUT2 one cut homeobox 2 0.330885