glaucoma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000501
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Genes

99 genes associated with the glaucoma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
LOXL1 lysyl oxidase-like 1 2.17573
ATOH7 atonal homolog 7 (Drosophila) 1.74205
CDKN2B-AS1 CDKN2B antisense RNA 1 1.68604
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.36571
LOC100506532 uncharacterized LOC100506532 1.36327
COL5A1 collagen, type V, alpha 1 1.34034
COL8A2 collagen, type VIII, alpha 2 1.32196
RERE arginine-glutamic acid dipeptide (RE) repeats 1.31934
SRBD1 S1 RNA binding domain 1 1.30781
ADPRHL2 ADP-ribosylhydrolase like 2 1.27399
ADAMTSL1 ADAMTS-like 1 1.2142
FNDC3B fibronectin type III domain containing 3B 1.14151
DCLK3 doublecortin-like kinase 3 1.13334
AKAP6 A kinase (PRKA) anchor protein 6 1.12043
IDO2 indoleamine 2,3-dioxygenase 2 1.10276
FAM53B family with sequence similarity 53, member B 1.09212
TRAPPC3 trafficking protein particle complex 3 1.07044
FAM175B family with sequence similarity 175, member B 1.06127
LINC00290 long intergenic non-protein coding RNA 290 1.02729
CDKN2A cyclin-dependent kinase inhibitor 2A 0.991558
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.901553
SDK1 sidekick cell adhesion molecule 1 0.894655
PIAS2 protein inhibitor of activated STAT, 2 0.860376
TMCO1 transmembrane and coiled-coil domains 1 0.765722
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.729881
GAS7 growth arrest-specific 7 0.572823
EBF4 early B-cell factor 4 0.50086
FAT3 FAT atypical cadherin 3 0.467973
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.433116
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.425601
PDE7B phosphodiesterase 7B 0.413807
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.413807
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.412621
LRRC4C leucine rich repeat containing 4C 0.411311
CSF1R colony stimulating factor 1 receptor 0.411115
BMPR1A bone morphogenetic protein receptor, type IA 0.410331
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.408206
FOXP1 forkhead box P1 0.406588
LOC100147773 uncharacterized LOC100147773 0.403666
SATB1 SATB homeobox 1 0.40201
AFAP1 actin filament associated protein 1 0.401355
COL11A1 collagen, type XI, alpha 1 0.391503
CRMP1 collapsin response mediator protein 1 0.391325
CAV2 caveolin 2 0.390424
DCLK1 doublecortin-like kinase 1 0.376528
CHEK2 checkpoint kinase 2 0.376528
BCAS3 breast carcinoma amplified sequence 3 0.36942
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.366534
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 0.358199
TXNRD2 thioredoxin reductase 2 0.356732
ATP8B5P ATPase, class I, type 8B, member 5, pseudogene 0.356442
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.35372
CADPS Ca++-dependent secretion activator 0.347251
PRKCH protein kinase C, eta 0.343616
ZNF827 zinc finger protein 827 0.339081
ITPKB inositol-trisphosphate 3-kinase B 0.338809
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.336588
LOC643339 uncharacterized LOC643339 0.336588
SIX6 SIX homeobox 6 0.335804
PTPRD protein tyrosine phosphatase, receptor type, D 0.335378
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.33503
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.334399
PDE4D phosphodiesterase 4D, cAMP-specific 0.33425
RGS6 regulator of G-protein signaling 6 0.331894
PLB1 phospholipase B1 0.331601
CPB1 carboxypeptidase B1 (tissue) 0.330814
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.329224
ANKRD44 ankyrin repeat domain 44 0.32493
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.324569
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.323763
FOCAD focadhesin 0.323201
RCAN2 regulator of calcineurin 2 0.316081
WDR82 WD repeat domain 82 0.315019
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.312711
FAM169B family with sequence similarity 169, member B 0.312711
DSTYK dual serine/threonine and tyrosine protein kinase 0.311538
RPSAP52 ribosomal protein SA pseudogene 52 0.307334
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.305894
NPAS3 neuronal PAS domain protein 3 0.305437
PARD3B par-3 family cell polarity regulator beta 0.304507
MTAP methylthioadenosine phosphorylase 0.302879
ZDHHC2 zinc finger, DHHC-type containing 2 0.301472
MAML2 mastermind-like 2 (Drosophila) 0.30029
SOD2 superoxide dismutase 2, mitochondrial 0.299086
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.298185
NWD2 NACHT and WD repeat domain containing 2 0.297705
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.297658
CDH13 cadherin 13 0.295814
LOC729911 0.295461
BBS9 Bardet-Biedl syndrome 9 0.295318
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.29474
PXDNL peroxidasin-like 0.294681
CSMD1 CUB and Sushi multiple domains 1 0.293263
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.282656
ZSWIM3 zinc finger, SWIM-type containing 3 0.279457
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 0.271243
GFAP glial fibrillary acidic protein 0.271005
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.256155
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.253708