ginkgolide A-3260 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ginkgolide A-3260 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABI2 abl-interactor 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALML3 calmodulin-like 3
CARD14 caspase recruitment domain family, member 14
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CFHR2 complement factor H-related 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLTC clathrin, heavy chain (Hc)
CPNE7 copine VII
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK2 death-associated protein kinase 2
DCAF15 DDB1 and CUL4 associated factor 15
DEPDC5 DEP domain containing 5
DES desmin
DIO2 deiodinase, iodothyronine, type II
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EFR3B EFR3 homolog B (S. cerevisiae)
FAS Fas cell surface death receptor
FLT4 fms-related tyrosine kinase 4
FOSL2 FOS-like antigen 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
INPP5J inositol polyphosphate-5-phosphatase J
IRF9 interferon regulatory factor 9
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC729164 hCG1732469
LOXL3 lysyl oxidase-like 3
LRRC15 leucine rich repeat containing 15
MAK male germ cell-associated kinase
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MUC3B mucin 3B, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEURL1 neuralized E3 ubiquitin protein ligase 1
NOP16 NOP16 nucleolar protein
NPY neuropeptide Y
NPY4R neuropeptide Y receptor Y4
NUMA1 nuclear mitotic apparatus protein 1
OAZ3 ornithine decarboxylase antizyme 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OXCT2 3-oxoacid CoA transferase 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PLA2G3 phospholipase A2, group III
PLAU plasminogen activator, urokinase
PLK3 polo-like kinase 3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PON1 paraoxonase 1
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PSG9 pregnancy specific beta-1-glycoprotein 9
RAB30 RAB30, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASAL2 RAS protein activator like 2
RGS12 regulator of G-protein signaling 12
RIMS3 regulating synaptic membrane exocytosis 3
RIN3 Ras and Rab interactor 3
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
RPLP2 ribosomal protein, large, P2
SCAND2P SCAN domain containing 2 pseudogene
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SPN sialophorin
SQSTM1 sequestosome 1
SUGP1 SURP and G patch domain containing 1
SYN2 synapsin II
SYT12 synaptotagmin XII
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TKTL1 transketolase-like 1
TMPRSS6 transmembrane protease, serine 6
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
USP46 ubiquitin specific peptidase 46
VWA5A von Willebrand factor A domain containing 5A
WDR59 WD repeat domain 59
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZEB1 zinc finger E-box binding homeobox 1
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACSS3 acyl-CoA synthetase short-chain family member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG9A autophagy related 9A
ATP11B ATPase, class VI, type 11B
ATP13A2 ATPase type 13A2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAHD1 bromo adjacent homology domain containing 1
BCL7B B-cell CLL/lymphoma 7B
BCL9 B-cell CLL/lymphoma 9
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMKMT calmodulin-lysine N-methyltransferase
CAPN15 calpain 15
CBX4 chromobox homolog 4
CCDC130 coiled-coil domain containing 130
CCDC88C coiled-coil domain containing 88C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP72 centrosomal protein 72kDa
CHPF chondroitin polymerizing factor
CRY2 cryptochrome circadian clock 2
CSTA cystatin A (stefin A)
CUEDC1 CUE domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAAF2 dynein, axonemal, assembly factor 2
DNAL4 dynein, axonemal, light chain 4
ELMO3 engulfment and cell motility 3
EXTL2 exostosin-like glycosyltransferase 2
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FBXL6 F-box and leucine-rich repeat protein 6
FBXO31 F-box protein 31
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMIP GEM interacting protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR87 G protein-coupled receptor 87
GUSBP3 glucuronidase, beta pseudogene 3
HMGXB3 HMG box domain containing 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGSF1 immunoglobulin superfamily, member 1
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KLHL12 kelch-like family member 12
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMNB1 lamin B1
LRP5 low density lipoprotein receptor-related protein 5
LY6D lymphocyte antigen 6 complex, locus D
MAN2C1 mannosidase, alpha, class 2C, member 1
MISP mitotic spindle positioning
MTCL1 microtubule crosslinking factor 1
MTERF4 mitochondrial transcription termination factor 4
MUM1 melanoma associated antigen (mutated) 1
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NECAP2 NECAP endocytosis associated 2
NLK nemo-like kinase
NUBPL nucleotide binding protein-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PNPLA6 patatin-like phospholipase domain containing 6
PRSS22 protease, serine, 22
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF122 ring finger protein 122
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAI suppressor of cancer cell invasion
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMTN smoothelin
SNHG20 small nucleolar RNA host gene 20
SPIDR scaffolding protein involved in DNA repair
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TESC tescalcin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
UNKL unkempt family zinc finger-like
VWA1 von Willebrand factor A domain containing 1
WDR76 WD repeat domain 76
ZBTB3 zinc finger and BTB domain containing 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF16 zinc finger protein 16
ZNF468 zinc finger protein 468
ZNF571 zinc finger protein 571
ZNF580 zinc finger protein 580
ZNF652 zinc finger protein 652
ZNF778 zinc finger protein 778