gestational diabetes Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

219 genes co-occuring with the disease gestational diabetes in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 2.75865
GLS2 glutaminase 2 (liver, mitochondrial) 2.20149
PRG4 proteoglycan 4 2.06487
GGCT gamma-glutamylcyclotransferase 1.7446
LEP leptin 1.69315
RBP4 retinol binding protein 4, plasma 1.42367
MTNR1B melatonin receptor 1B 1.41052
NAMPT nicotinamide phosphoribosyltransferase 1.36335
CSH2 chorionic somatomammotropin hormone 2 1.32279
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.32105
GCK glucokinase (hexokinase 4) 1.25341
RETN resistin 1.21392
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.191
INSR insulin receptor 1.11603
IRS1 insulin receptor substrate 1 1.09503
SHBG sex hormone-binding globulin 1.06816
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.06228
CRP C-reactive protein, pentraxin-related 1.06144
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.01005
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.00457
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.968761
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.961634
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.95996
C18ORF21 chromosome 18 open reading frame 21 0.931242
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.909376
GCG glucagon 0.906086
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.8741
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.865502
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 0.849126
LOXL2 lysyl oxidase-like 2 0.845031
VEPH1 ventricular zone expressed PH domain-containing 1 0.824948
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.808949
NADK NAD kinase 0.796232
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.792541
HBA1 hemoglobin, alpha 1 0.781479
LYPD6 LY6/PLAUR domain containing 6 0.779432
HBA2 hemoglobin, alpha 2 0.778204
CXCL9 chemokine (C-X-C motif) ligand 9 0.74761
HNF1A HNF1 homeobox A 0.745578
SPTB spectrin, beta, erythrocytic 0.737054
ITLN1 intelectin 1 (galactofuranose binding) 0.735027
PPARG peroxisome proliferator-activated receptor gamma 0.729762
ENHO energy homeostasis associated 0.724502
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.722077
HAND2 heart and neural crest derivatives expressed 2 0.718039
HKDC1 hexokinase domain containing 1 0.712796
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.705949
FGF21 fibroblast growth factor 21 0.700722
IGF1 insulin-like growth factor 1 (somatomedin C) 0.695504
EDF1 endothelial differentiation-related factor 1 0.677903
GBX1 gastrulation brain homeobox 1 0.65763
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.65565
ADRB3 adrenoceptor beta 3 0.653671
FTL ferritin, light polypeptide 0.649718
FTH1 ferritin, heavy polypeptide 1 0.649718
LEPR leptin receptor 0.634742
ALB albumin 0.62885
ADIPOR2 adiponectin receptor 2 0.628457
GIP gastric inhibitory polypeptide 0.624535
GAL galanin/GMAP prepropeptide 0.622575
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.612792
FABP4 fatty acid binding protein 4, adipocyte 0.611229
IRS2 insulin receptor substrate 2 0.610838
TNF tumor necrosis factor 0.610057
SMG8 SMG8 nonsense mediated mRNA decay factor 0.608494
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.608494
MGAM maltase-glucoamylase 0.606933
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.605762
LPL lipoprotein lipase 0.605762
NOL9 nucleolar protein 9 0.588222
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.587444
PPAN peter pan homolog (Drosophila) 0.587444
ZDHHC23 zinc finger, DHHC-type containing 23 0.587444
IL6 interleukin 6 0.57655
FTO fat mass and obesity associated 0.574605
GH1 growth hormone 1 0.566831
HHEX hematopoietically expressed homeobox 0.566054
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.556732
PTPRN protein tyrosine phosphatase, receptor type, N 0.550911
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.545868
LAD1 ladinin 1 0.543542
FAM46C family with sequence similarity 46, member C 0.540055
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.538893
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 0.526904
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.516494
PIH2 pregnancy-induced hypertension syndrome-related protein 0.515725
ACP1 acid phosphatase 1, soluble 0.51534
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.51534
GHRL ghrelin/obestatin prepropeptide 0.507657
ELL elongation factor RNA polymerase II 0.502292
ADIPOR1 adiponectin receptor 1 0.499614
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.494648
DBNL drebrin-like 0.493503
HNF4A hepatocyte nuclear factor 4, alpha 0.484744
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.483985
CAPN10 calpain 10 0.472225
IAPP islet amyloid polypeptide 0.467684
MOB1A MOB kinase activator 1A 0.462772
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.458996
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.458619
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.453716
PAEP progestagen-associated endometrial protein 0.452585
IGF2 insulin-like growth factor 2 0.449947
PRSS21 protease, serine, 21 (testisin) 0.449194
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.446935
SELE selectin E 0.443923
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.437154
AKR1C4 aldo-keto reductase family 1, member C4 0.436402
ACOT7 acyl-CoA thioesterase 7 0.434899
IGFBP1 insulin-like growth factor binding protein 1 0.434899
C6ORF25 chromosome 6 open reading frame 25 0.429266
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.424014
GGT1 gamma-glutamyltransferase 1 0.423265
INSIG1 insulin induced gene 1 0.422515
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.409414
SAMD4B sterile alpha motif domain containing 4B 0.407919
INSM2 insulinoma-associated 2 0.405305
NOS3 nitric oxide synthase 3 (endothelial cell) 0.404931
LGI2 leucine-rich repeat LGI family, member 2 0.394491
MEGF6 multiple EGF-like-domains 6 0.394118
ICAM1 intercellular adhesion molecule 1 0.385565
APOB apolipoprotein B 0.384822
GPR183 G protein-coupled receptor 183 0.383708
SLURP1 secreted LY6/PLAUR domain containing 1 0.383708
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.379256
WRAP73 WD repeat containing, antisense to TP73 0.374438
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.370368
MIR222 microRNA 222 0.359657
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.359657
GDF1 growth differentiation factor 1 0.358551
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.356341
MED13L mediator complex subunit 13-like 0.353763
PGF placental growth factor 0.347144
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.342739
LGI3 leucine-rich repeat LGI family, member 3 0.340539
PTPRD protein tyrosine phosphatase, receptor type, D 0.33651
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.335412
APEH acylaminoacyl-peptide hydrolase 0.32373
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.322273
GPX1 glutathione peroxidase 1 0.31029
SDS serine dehydratase 0.307757
APOA1 apolipoprotein A-I 0.305226
VCAM1 vascular cell adhesion molecule 1 0.300173
ATAD3A ATPase family, AAA domain containing 3A 0.299092
PLG plasminogen 0.295851
ATE1 arginyltransferase 1 0.295132
VPREB1 pre-B lymphocyte 1 0.294413
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.292257
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.28294
MARCKSL1 MARCKS-like 1 0.282225
STARD3 StAR-related lipid transfer (START) domain containing 3 0.280439
GPX5 glutathione peroxidase 5 0.280439
MTNR1A melatonin receptor 1A 0.279724
GPX4 glutathione peroxidase 4 0.277584
CPB2 carboxypeptidase B2 (plasma) 0.277227
HK1 hexokinase 1 0.274021
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.270819
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.270464
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.269043
KAT7 K(lysine) acetyltransferase 7 0.264431
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 0.263368
CBR3 carbonyl reductase 3 0.262306
LIPG lipase, endothelial 0.261952
APLN apelin 0.258064
PLAA phospholipase A2-activating protein 0.254536
CFC1 cripto, FRL-1, cryptic family 1 0.252774
ARNT aryl hydrocarbon receptor nuclear translocator 0.252774
THUMPD1 THUMP domain containing 1 0.251718
CAT catalase 0.251718
PER1 period circadian clock 1 0.250311
CATSPER1 cation channel, sperm associated 1 0.248554
OMA1 OMA1 zinc metallopeptidase 0.244345
PYCR1 pyrroline-5-carboxylate reductase 1 0.240847
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.23945
PLAT plasminogen activator, tissue 0.238054
PER2 period circadian clock 2 0.237706
SLC38A1 solute carrier family 38, member 1 0.237706
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.237009
SEPW1 selenoprotein W, 1 0.23492
PPY pancreatic polypeptide 0.232489
PARL presenilin associated, rhomboid-like 0.232489
TF transferrin 0.232142
SOD2 superoxide dismutase 2, mitochondrial 0.231448
GYS2 glycogen synthase 2 (liver) 0.22454
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.223853
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.221108
GZMM granzyme M (lymphocyte met-ase 1) 0.218715
ADGRE1 adhesion G protein-coupled receptor E1 0.215992
SLC38A2 solute carrier family 38, member 2 0.214636
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.213959
AFP alpha-fetoprotein 0.211261
FOXC2 forkhead box C2 0.207912
NEUROG3 neurogenin 3 0.204923
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.200656
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.200331
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.200006
THAP3 THAP domain containing, apoptosis associated protein 3 0.200006
DSPP dentin sialophosphoprotein 0.198064
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.194548
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.187113
ARSI arylsulfatase family, member I 0.185612
LIG3 ligase III, DNA, ATP-dependent 0.185313
DACT3 dishevelled-binding antagonist of beta-catenin 3 0.183541
TPH1 tryptophan hydroxylase 1 0.178403
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.177301
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.176485
FLT1 fms-related tyrosine kinase 1 0.175679
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.172038
CNOT2 CCR4-NOT transcription complex, subunit 2 0.170299
HMX1 H6 family homeobox 1 0.16933
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.168617
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.165874
ANGPTL4 angiopoietin-like 4 0.165655
PNPLA2 patatin-like phospholipase domain containing 2 0.165435
CSN1S1 casein alpha s1 0.164786
HBD hemoglobin, delta 0.161912
PRLR prolactin receptor 0.161523
ESR2 estrogen receptor 2 (ER beta) 0.160203
GGT2 gamma-glutamyltransferase 2 0.158951