germinal epithelium Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Epithelium covering the embryonic genital ridges and the gonads that develop from them. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004524)
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Genes

311 proteins co-occuring with the tissue germinal epithelium in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.90343
MUC16 mucin 16, cell surface associated 1.75874
MUC4 mucin 4, cell surface associated 1.39376
MUC1 mucin 1, cell surface associated 1.37179
KRT7 keratin 7, type II 1.32732
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.31739
MUC2 mucin 2, oligomeric mucus/gel-forming 1.29624
MUC6 mucin 6, oligomeric mucus/gel-forming 1.28636
MUC7 mucin 7, secreted 1.26442
KRT20 keratin 20, type I 1.26173
TFF2 trefoil factor 2 1.17935
TP53 tumor protein p53 1.13944
ESR1 estrogen receptor 1 1.12792
PCNA proliferating cell nuclear antigen 1.07265
PGR progesterone receptor 1.06074
AQP12B aquaporin 12B 1.012
DEFB113 defensin, beta 113 0.995425
GAST gastrin 0.95384
INHA inhibin, alpha 0.942645
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.938347
ACPP acid phosphatase, prostate 0.910946
LDHC lactate dehydrogenase C 0.865155
C19ORF33 chromosome 19 open reading frame 33 0.86347
MUC17 mucin 17, cell surface associated 0.852527
CD79A CD79a molecule, immunoglobulin-associated alpha 0.844126
AQP3 aquaporin 3 (Gill blood group) 0.842027
TRO trophinin 0.837833
ALPP alkaline phosphatase, placental 0.83448
ALPPL2 alkaline phosphatase, placental-like 2 0.818158
ALPL alkaline phosphatase, liver/bone/kidney 0.817322
AR androgen receptor 0.812726
LACRT lacritin 0.806882
TFF3 trefoil factor 3 (intestinal) 0.806047
DNAH8 dynein, axonemal, heavy chain 8 0.801459
CDX2 caudal type homeobox 2 0.77774
ATG101 autophagy related 101 0.776909
KRT12 keratin 12, type I 0.765711
WT1 Wilms tumor 1 0.764882
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.762811
C6ORF15 chromosome 6 open reading frame 15 0.758259
TROAP trophinin associated protein 0.743801
DEFB4A defensin, beta 4A 0.741327
IVL involucrin 0.74009
AQP5 aquaporin 5 0.736794
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.736382
ESR2 estrogen receptor 2 (ER beta) 0.731854
CAMP cathelicidin antimicrobial peptide 0.73062
EGFR epidermal growth factor receptor 0.728152
DEFB1 defensin, beta 1 0.72733
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.705173
UPK3A uroplakin 3A 0.703536
BAG5 BCL2-associated athanogene 5 0.694946
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa 0.694537
TFF1 trefoil factor 1 0.692085
MMP2 matrix metallopeptidase 2 0.688817
LYZ lysozyme 0.688409
CD68 CD68 molecule 0.688
MMP9 matrix metallopeptidase 9 0.685959
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.685959
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.684327
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 0.67658
DEFA6 defensin, alpha 6, Paneth cell-specific 0.675357
ANO6 anoctamin 6 0.675357
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.673321
TTF1 transcription termination factor, RNA polymerase I 0.659897
ACSL5 acyl-CoA synthetase long-chain family member 5 0.658678
AQP7 aquaporin 7 0.65746
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.656242
OVCA2 ovarian tumor suppressor candidate 2 0.655024
TLR3 toll-like receptor 3 0.64529
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.640833
FABP1 fatty acid binding protein 1, liver 0.640833
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.639619
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 0.635572
KRT3 keratin 3, type II 0.635167
CA2 carbonic anhydrase II 0.634762
UPK1B uroplakin 1B 0.625061
DNTT DNA nucleotidylexotransferase 0.619007
ZNF253 zinc finger protein 253 0.612958
BPIFA1 BPI fold containing family A, member 1 0.612152
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 0.599675
IGHV1-2 immunoglobulin heavy variable 1-2 0.59646
TJP1 tight junction protein 1 0.586427
SFTPA2 surfactant protein A2 0.585224
AQP11 aquaporin 11 0.584823
RTP4 receptor (chemosensory) transporter protein 4 0.583621
IGFBP1 insulin-like growth factor binding protein 1 0.581218
TMLHE trimethyllysine hydroxylase, epsilon 0.581218
CHGA chromogranin A 0.581218
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.580017
IGFBP5 insulin-like growth factor binding protein 5 0.579216
KRT14 keratin 14, type I 0.57042
MUC13 mucin 13, cell surface associated 0.565232
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.56284
LTF lactotransferrin 0.56005
FN1 fibronectin 1 0.556467
CLDN8 claudin 8 0.54812
FLG filaggrin 0.547724
CLCA1 chloride channel accessory 1 0.545342
DEFB104B defensin, beta 104B 0.54217
SHBG sex hormone-binding globulin 0.541377
IL1B interleukin 1, beta 0.531089
KRT18 keratin 18, type I 0.527139
FSHR follicle stimulating hormone receptor 0.52635
TMEM259 transmembrane protein 259 0.5228
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.521617
KRT8 keratin 8, type II 0.518465
CD4 CD4 molecule 0.518465
RXRB retinoid X receptor, beta 0.516891
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.516497
BRI3 brain protein I3 0.51571
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.51453
SPRR1B small proline-rich protein 1B 0.514136
SPP1 secreted phosphoprotein 1 0.511778
FTL ferritin, light polypeptide 0.510992
COL7A1 collagen, type VII, alpha 1 0.510992
PAX6 paired box 6 0.505102
AQP8 aquaporin 8 0.50471
LAP3 leucine aminopeptidase 3 0.50471
HRH2 histamine receptor H2 0.503926
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.503533
FTH1 ferritin, heavy polypeptide 1 0.503533
CLCA4 chloride channel accessory 4 0.501965
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.501574
KRT13 keratin 13, type I 0.494918
APCDD1 adenomatosis polyposis coli down-regulated 1 0.492182
EPCAM epithelial cell adhesion molecule 0.489057
LAMB2 laminin, beta 2 (laminin S) 0.482817
CDKN2A cyclin-dependent kinase inhibitor 2A 0.481648
BCL2 B-cell CLL/lymphoma 2 0.476589
CLCA2 chloride channel accessory 2 0.472315
TGFB1 transforming growth factor, beta 1 0.471539
MMP7 matrix metallopeptidase 7 0.471151
ERBB2 erb-b2 receptor tyrosine kinase 2 0.471151
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.470763
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.468436
BRCA1 breast cancer 1, early onset 0.46766
MED15 mediator complex subunit 15 0.465335
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.464561
ERBB3 erb-b2 receptor tyrosine kinase 3 0.463013
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.462239
CCL20 chemokine (C-C motif) ligand 20 0.460692
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.457987
TNF tumor necrosis factor 0.456055
ANKK1 ankyrin repeat and kinase domain containing 1 0.455284
KLF4 Kruppel-like factor 4 (gut) 0.455284
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.454512
SOD2 superoxide dismutase 2, mitochondrial 0.452969
SPATA7 spermatogenesis associated 7 0.449501
IFI30 interferon, gamma-inducible protein 30 0.449116
NCAM1 neural cell adhesion molecule 1 0.446422
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.446422
VIP vasoactive intestinal peptide 0.446038
LCN1 lipocalin 1 0.444499
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.442962
ALB albumin 0.442578
IGF1 insulin-like growth factor 1 (somatomedin C) 0.44181
ICAM1 intercellular adhesion molecule 1 0.441042
TAC1 tachykinin, precursor 1 0.434523
AZIN1 antizyme inhibitor 1 0.43414
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.431843
ITGA6 integrin, alpha 6 0.428401
GJA1 gap junction protein, alpha 1, 43kDa 0.425726
KRT5 keratin 5, type II 0.425726
SST somatostatin 0.422292
CD44 CD44 molecule (Indian blood group) 0.414293
ODC1 ornithine decarboxylase 1 0.413532
LEAP2 liver expressed antimicrobial peptide 2 0.412771
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.412011
COL4A1 collagen, type IV, alpha 1 0.411251
ERBB4 erb-b2 receptor tyrosine kinase 4 0.410491
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.410491
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.408212
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.408212
LGALS3 lectin, galactoside-binding, soluble, 3 0.402144
SFTPA1 surfactant protein A1 0.40025
PGC progastricsin (pepsinogen C) 0.392309
MUC19 mucin 19, oligomeric 0.391553
TSPO translocator protein (18kDa) 0.390799
CCND1 cyclin D1 0.389666
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.386273
LEF1 lymphoid enhancer-binding factor 1 0.385143
MKI67 marker of proliferation Ki-67 0.384766
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.38326
AQP4 aquaporin 4 0.38326
TNC tenascin C 0.382131
DMRT1 doublesex and mab-3 related transcription factor 1 0.381003
MUC20 mucin 20, cell surface associated 0.378748
SYCP3 synaptonemal complex protein 3 0.377996
CA3 carbonic anhydrase III 0.377996
RMDN3 regulator of microtubule dynamics 3 0.375743
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.374993
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.373118
HAVCR2 hepatitis A virus cellular receptor 2 0.371245
SALL2 spalt-like transcription factor 2 0.367502
KRAS Kirsten rat sarcoma viral oncogene homolog 0.367129
FBRS fibrosin 0.366754
TIMP1 TIMP metallopeptidase inhibitor 1 0.365633
CRABP1 cellular retinoic acid binding protein 1 0.361155
GLB1 galactosidase, beta 1 0.360036
PRSS8 protease, serine, 8 0.359292
MMP1 matrix metallopeptidase 1 0.351485
AQP12A aquaporin 12A 0.351485
ELANE elastase, neutrophil expressed 0.351114
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.348148
GCG glucagon 0.347408
TLR5 toll-like receptor 5 0.347038
DPH1 diphthamide biosynthesis 1 0.347038
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.34334
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.337808
EPYC epiphycan 0.335968
MUC12 mucin 12, cell surface associated 0.335968
CALB2 calbindin 2 0.335233
FCGBP Fc fragment of IgG binding protein 0.335233
PRR4 proline rich 4 (lacrimal) 0.33046
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.330094
LDHB lactate dehydrogenase B 0.328628
THBS1 thrombospondin 1 0.326067
SDC1 syndecan 1 0.325335
DPP4 dipeptidyl-peptidase 4 0.324605
RSAD2 radical S-adenosyl methionine domain containing 2 0.322779
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.319134
WNK3 WNK lysine deficient protein kinase 3 0.316951
TLR2 toll-like receptor 2 0.315498
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.314046
FBXO5 F-box protein 5 0.312232
PAEP progestagen-associated endometrial protein 0.311145
OCLN occludin 0.310059
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.309335
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.306083
JAG1 jagged 1 0.305722
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.303919
IL11RA interleukin 11 receptor, alpha 0.301398
GUSB glucuronidase, beta 0.301039
CXCL10 chemokine (C-X-C motif) ligand 10 0.294223
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 0.293866
ENO2 enolase 2 (gamma, neuronal) 0.292436
RBP1 retinol binding protein 1, cellular 0.292079
CLDN7 claudin 7 0.287447
IFI44 interferon-induced protein 44 0.286381
CLDN14 claudin 14 0.285671
CLDN1 claudin 1 0.285671
SPRR1A small proline-rich protein 1A 0.282837
GHRL ghrelin/obestatin prepropeptide 0.281776
KRTAP11-1 keratin associated protein 11-1 0.280364
CLEC2B C-type lectin domain family 2, member B 0.279659
WNT10A wingless-type MMTV integration site family, member 10A 0.278955
ADM adrenomedullin 0.278603
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.277549
CXCL8 chemokine (C-X-C motif) ligand 8 0.275794
KRT4 keratin 4, type II 0.274045
NOS3 nitric oxide synthase 3 (endothelial cell) 0.273696
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 0.273346
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.271952
MATN2 matrilin 2 0.271604
CMA1 chymase 1, mast cell 0.269521
FOSL1 FOS-like antigen 1 0.269174
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.268828
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.268137
HRAS Harvey rat sarcoma viral oncogene homolog 0.264011
COL18A1 collagen, type XVIII, alpha 1 0.263669
CTSE cathepsin E 0.263327
MUC3A mucin 3A, cell surface associated 0.263327
NOTCH1 notch 1 0.262645
CLEC3B C-type lectin domain family 3, member B 0.262645
DSP desmoplakin 0.262304
CCL4 chemokine (C-C motif) ligand 4 0.261284
CXCL11 chemokine (C-X-C motif) ligand 11 0.260267
CTSG cathepsin G 0.258917
CAT catalase 0.258917
HTN1 histatin 1 0.258917
NID1 nidogen 1 0.257907
BIRC5 baculoviral IAP repeat containing 5 0.257572
TEN1 TEN1 CST complex subunit 0.256234
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.2559
RNASEH2A ribonuclease H2, subunit A 0.254239
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.245807
IHH indian hedgehog 0.245175
KRT19 keratin 19, type I 0.24486
MFGE8 milk fat globule-EGF factor 8 protein 0.243918
GRP gastrin-releasing peptide 0.243294
DAZL deleted in azoospermia-like 0.24052
NANOS2 nanos homolog 2 (Drosophila) 0.23961
HAMP hepcidin antimicrobial peptide 0.238706
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.238706
MUC15 mucin 15, cell surface associated 0.238108
RAD17 RAD17 homolog (S. pombe) 0.238108
NKX2-1 NK2 homeobox 1 0.237216
HGFAC HGF activator 0.236921
KLF5 Kruppel-like factor 5 (intestinal) 0.23604
IL1A interleukin 1, alpha 0.235167
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.23459
KLK1 kallikrein 1 0.233731
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.232039
BCOR BCL6 corepressor 0.230656
GSTZ1 glutathione S-transferase zeta 1 0.227707
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.227186
TLR4 toll-like receptor 4 0.227186
SAFB scaffold attachment factor B 0.226926
EREG epiregulin 0.221291
ANO1 anoctamin 1, calcium activated chloride channel 0.21883
CLDN5 claudin 5 0.218613
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.217554
AFP alpha-fetoprotein 0.217346
PHYH phytanoyl-CoA 2-hydroxylase 0.217139
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.21573
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.215534
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.214765
SMAD4 SMAD family member 4 0.214576
PAX2 paired box 2 0.213833
S100G S100 calcium binding protein G 0.212761