gentamicin-7237 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the gentamicin-7237 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM8 ADAM metallopeptidase domain 8
AJAP1 adherens junctions associated protein 1
AK2 adenylate kinase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAX BCL2-associated X protein
BBS9 Bardet-Biedl syndrome 9
BCORL1 BCL6 corepressor-like 1
BDKRB2 bradykinin receptor B2
BIRC7 baculoviral IAP repeat containing 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C2ORF68 chromosome 2 open reading frame 68
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHD5 chromodomain helicase DNA binding protein 5
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOK4 docking protein 4
EFNA3 ephrin-A3
EYA3 EYA transcriptional coactivator and phosphatase 3
FSCN3 fascin actin-bundling protein 3, testicular
FYB FYN binding protein
GAL galanin/GMAP prepropeptide
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GSK3A glycogen synthase kinase 3 alpha
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
HOXD1 homeobox D1
HSPA1L heat shock 70kDa protein 1-like
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFT122 intraflagellar transport 122
IGFBP5 insulin-like growth factor binding protein 5
IL1B interleukin 1, beta
ING1 inhibitor of growth family, member 1
JAK2 Janus kinase 2
KAT8 K(lysine) acetyltransferase 8
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KITLG KIT ligand
KLHL22 kelch-like family member 22
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MUSK muscle, skeletal, receptor tyrosine kinase
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
OMG oligodendrocyte myelin glycoprotein
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PDLIM5 PDZ and LIM domain 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP prolactin-induced protein
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POPDC3 popeye domain containing 3
PROX1 prospero homeobox 1
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RBM3 RNA binding motif (RNP1, RRM) protein 3
RDH16 retinol dehydrogenase 16 (all-trans)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
S100A8 S100 calcium binding protein A8
SAMD4A sterile alpha motif domain containing 4A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPHK2 sphingosine kinase 2
SSPN sarcospan
TCF4 transcription factor 4
TDRKH tudor and KH domain containing
TLN2 talin 2
TLX2 T-cell leukemia homeobox 2
TMOD1 tropomodulin 1
TNK2 tyrosine kinase, non-receptor, 2
UBE2I ubiquitin-conjugating enzyme E2I
UBE3A ubiquitin protein ligase E3A
USP2 ubiquitin specific peptidase 2
UTRN utrophin
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WDR78 WD repeat domain 78
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZNF286A zinc finger protein 286A
ZNF589 zinc finger protein 589
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ASTN2 astrotactin 2
BCAS1 breast carcinoma amplified sequence 1
BFSP1 beaded filament structural protein 1, filensin
BRAF B-Raf proto-oncogene, serine/threonine kinase
C2ORF54 chromosome 2 open reading frame 54
C9ORF40 chromosome 9 open reading frame 40
CAPG capping protein (actin filament), gelsolin-like
CCDC88C coiled-coil domain containing 88C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDKL3 cyclin-dependent kinase-like 3
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIR1 corepressor interacting with RBPJ, 1
CLCF1 cardiotrophin-like cytokine factor 1
CLDN15 claudin 15
COG4 component of oligomeric golgi complex 4
CRLF1 cytokine receptor-like factor 1
DUSP2 dual specificity phosphatase 2
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM189B family with sequence similarity 189, member B
FAM192A family with sequence similarity 192, member A
FBXO2 F-box protein 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GID4 GID complex subunit 4
GMEB1 glucocorticoid modulatory element binding protein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
HIST1H2BO histone cluster 1, H2bo
HMHA1 histocompatibility (minor) HA-1
IGSF1 immunoglobulin superfamily, member 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
KAT2A K(lysine) acetyltransferase 2A
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIF13B kinesin family member 13B
KLHL36 kelch-like family member 36
LHX1 LIM homeobox 1
LINC00339 long intergenic non-protein coding RNA 339
LYPLA2P1 lysophospholipase II pseudogene 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MB myoglobin
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MUC3A mucin 3A, cell surface associated
NEK11 NIMA-related kinase 11
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHGB5 protocadherin gamma subfamily B, 5
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PTDSS2 phosphatidylserine synthase 2
PUS3 pseudouridylate synthase 3
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RANBP17 RAN binding protein 17
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFX7 regulatory factor X, 7
RIN2 Ras and Rab interactor 2
RNASEH2B ribonuclease H2, subunit B
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
ROM1 retinal outer segment membrane protein 1
RPGR retinitis pigmentosa GTPase regulator
S100A4 S100 calcium binding protein A4
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D4A SH2 domain containing 4A
SIK1 salt-inducible kinase 1
SIPA1 signal-induced proliferation-associated 1
SLC12A8 solute carrier family 12, member 8
SLC35F5 solute carrier family 35, member F5
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNIP1 Smad nuclear interacting protein 1
SPAG7 sperm associated antigen 7
SRPX sushi-repeat containing protein, X-linked
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TOM1 target of myb1 (chicken)
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZNF141 zinc finger protein 141
ZNF16 zinc finger protein 16
ZNF468 zinc finger protein 468
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768