generalized Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

182 genes co-occuring with the biological term generalized in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABAT 4-aminobutyrate aminotransferase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACE angiotensin I converting enzyme
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANTXR1 anthrax toxin receptor 1
APP amyloid beta (A4) precursor protein
APTX aprataxin
ARX aristaless related homeobox
ATM ATM serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
BEST1 bestrophin 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C12ORF10 chromosome 12 open reading frame 10
C3 complement component 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMP cathelicidin antimicrobial peptide
CARD14 caspase recruitment domain family, member 14
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCBE1 collagen and calcium binding EGF domains 1
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CDKL5 cyclin-dependent kinase-like 5
CDSN corneodesmosin
CEP250 centrosomal protein 250kDa
CFH complement factor H
CHD2 chromodomain helicase DNA binding protein 2
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRM3 cholinergic receptor, muscarinic 3
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLCN2 chloride channel, voltage-sensitive 2
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL17A1 collagen, type XVII, alpha 1
COL7A1 collagen, type VII, alpha 1
COMT catechol-O-methyltransferase
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSC cathepsin C
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DEL15Q11.2 Chromosome 15q11.2 deletion syndrome
DEL15Q13.3 Chromosome 15q13.3 microdeletion syndrome
DEL17Q12 Chromosome 17q12 deletion syndrome
DPP4 dipeptidyl-peptidase 4
DRD2 dopamine receptor D2
DTNBP1 dystrobrevin binding protein 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EGFR epidermal growth factor receptor
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
FAM83H family with sequence similarity 83, member H
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGF13 fibroblast growth factor 13
FLT4 fms-related tyrosine kinase 4
FOPNL FGFR1OP N-terminal like
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXC2 forkhead box C2
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FRZB frizzled-related protein
FTL ferritin, light polypeptide
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GMPPB GDP-mannose pyrophosphorylase B
GPR143 G protein-coupled receptor 143
GRM4 glutamate receptor, metabotropic 4
GUCA1A guanylate cyclase activator 1A (retina)
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IFNG interferon, gamma
IL10 interleukin 10
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNT1 potassium channel, sodium activated subfamily T, member 1
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LMNA lamin A/C
MAGT1 magnesium transporter 1
MAOA monoamine oxidase A
MBL2 mannose-binding lectin (protein C) 2, soluble
MECP2 methyl CpG binding protein 2
MIR155 microRNA 155
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MYOT myotilin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NLRP1 NLR family, pyrin domain containing 1
NPAP1 nuclear pore associated protein 1
NPPC natriuretic peptide C
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN1 neurexin 1
OXT oxytocin/neurophysin I prepropeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PLAT plasminogen activator, tissue
PNPO pyridoxamine 5'-phosphate oxidase
PON1 paraoxonase 1
PSEN1 presenilin 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTK2 protein tyrosine kinase 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTRF polymerase I and transcript release factor
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS2 regulator of G-protein signaling 2
RHOA ras homolog family member A
S100B S100 calcium binding protein B
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMOC2 SPARC related modular calcium binding 2
SNAP25 synaptosomal-associated protein, 25kDa
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THAP1 THAP domain containing, apoptosis associated protein 1
THRB thyroid hormone receptor, beta
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TOR1A torsin family 1, member A (torsin A)
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TSLP thymic stromal lymphopoietin
TUBB4A tubulin, beta 4A class IVa
TYR tyrosinase
UCN urocortin
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCAM1 vascular cell adhesion molecule 1
VRK2 vaccinia related kinase 2
XBP1 X-box binding protein 1
ZEB2 zinc finger E-box binding homeobox 2