gastrointestinal stromal tumor Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_9253)
Similar Terms
Downloads & Tools

Genes

213 genes co-occuring with the disease gastrointestinal stromal tumor in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 3.28462
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.0921
ANO1 anoctamin 1, calcium activated chloride channel 2.42892
CD34 CD34 molecule 2.41498
KCTD12 potassium channel tetramerization domain containing 12 1.73186
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.52248
NF1 neurofibromin 1 1.43157
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.35463
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.34722
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.31187
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.16179
ETV1 ets variant 1 1.08957
CALD1 caldesmon 1 1.08327
PEX11B peroxisomal biogenesis factor 11 beta 1.08202
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 1.03577
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.03198
IGF1R insulin-like growth factor 1 receptor 1.02903
ENO2 enolase 2 (gamma, neuronal) 1.00246
RET ret proto-oncogene 0.981794
ZNF250 zinc finger protein 250 0.963309
TYRO3 TYRO3 protein tyrosine kinase 0.954108
ZNF91 zinc finger protein 91 0.943274
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.926692
TMEM204 transmembrane protein 204 0.899514
ADGRD1 adhesion G protein-coupled receptor D1 0.899514
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.894589
TP53 tumor protein p53 0.883521
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.873281
ZNF43 zinc finger protein 43 0.864684
CDKN2A cyclin-dependent kinase inhibitor 2A 0.838066
RBPMS2 RNA binding protein with multiple splicing 2 0.822077
SYP synaptophysin 0.813052
PRUNE2 prune homolog 2 (Drosophila) 0.811001
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.808539
FLT3 fms-related tyrosine kinase 3 0.804026
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.794181
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.788442
ZNF569 zinc finger protein 569 0.778613
ZNF763 zinc finger protein 763 0.778613
ZNF629 zinc finger protein 629 0.778613
ZNF501 zinc finger protein 501 0.778613
KITLG KIT ligand 0.77207
ZNF44 zinc finger protein 44 0.764718
CA11 carbonic anhydrase XI 0.753306
BCL6B B-cell CLL/lymphoma 6, member B 0.74761
KCTD10 potassium channel tetramerization domain containing 10 0.729357
COL22A1 collagen, type XXII, alpha 1 0.720461
MLANA melan-A 0.701526
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 0.685091
TP63 tumor protein p63 0.684692
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.675909
VEGFA vascular endothelial growth factor A 0.671527
ZNF436 zinc finger protein 436 0.6608
RAD54L2 RAD54-like 2 (S. cerevisiae) 0.631598
FSCN3 fascin actin-bundling protein 3, testicular 0.631598
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.616703
ZNF189 zinc finger protein 189 0.605372
FSCN2 fascin actin-bundling protein 2, retinal 0.604201
IGF2 insulin-like growth factor 2 0.60147
APOLD1 apolipoprotein L domain containing 1 0.589779
ANXA8L1 annexin A8-like 1 0.578106
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.564112
NF2 neurofibromin 2 (merlin) 0.558674
CLEC11A C-type lectin domain family 11, member A 0.556732
ALK anaplastic lymphoma receptor tyrosine kinase 0.543155
PCNA proliferating cell nuclear antigen 0.537731
MIR221 microRNA 221 0.528449
KIRREL3 kin of IRRE like 3 (Drosophila) 0.52729
HRAS Harvey rat sarcoma viral oncogene homolog 0.521502
ST7L suppression of tumorigenicity 7 like 0.518034
KRAS Kirsten rat sarcoma viral oncogene homolog 0.516494
FSCN1 fascin actin-bundling protein 1 0.504973
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.479047
SDHAF1 succinate dehydrogenase complex assembly factor 1 0.472225
LIN52 lin-52 DREAM MuvB core complex component 0.463905
PTEN phosphatase and tensin homolog 0.455978
RASD2 RASD family, member 2 0.448817
RGPD1 RANBP2-like and GRIP domain containing 1 0.448064
CTAG1A cancer/testis antigen 1A 0.445805
CTAG1B cancer/testis antigen 1B 0.43227
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.429266
CD68 CD68 molecule 0.42589
EGFR epidermal growth factor receptor 0.424014
NCAM1 neural cell adhesion molecule 1 0.42364
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.420641
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.419892
ALLC allantoicase 0.417644
CCND1 cyclin D1 0.41727
ZFP64 ZFP64 zinc finger protein 0.41465
HBA2 hemoglobin, alpha 2 0.412405
ERBB2 erb-b2 receptor tyrosine kinase 2 0.406051
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.402692
PEBP1 phosphatidylethanolamine binding protein 1 0.402318
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.400826
GLI1 GLI family zinc finger 1 0.399334
MFAP4 microfibrillar-associated protein 4 0.398962
CDK4 cyclin-dependent kinase 4 0.392257
GAN gigaxonin 0.389653
CD44 CD44 molecule (Indian blood group) 0.389281
HBA1 hemoglobin, alpha 1 0.386679
KCNRG potassium channel regulator 0.382966
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.378885
ANO6 anoctamin 6 0.378143
FER fer (fps/fes related) tyrosine kinase 0.374809
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.373698
RGS16 regulator of G-protein signaling 16 0.366671
GPC6 glypican 6 0.360764
CSF1R colony stimulating factor 1 receptor 0.356709
LOC102724852 uncharacterized LOC102724852 0.355972
MAGEA4 melanoma antigen family A4 0.355604
KDR kinase insert domain receptor 0.350084
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.344574
MAGEC1 melanoma antigen family C1 0.336144
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.335046
AURKA aurora kinase A 0.334681
RAB27B RAB27B, member RAS oncogene family 0.333583
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.327375
SDPR serum deprivation response 0.32701
ZNF222 zinc finger protein 222 0.325916
CHGA chromogranin A 0.323365
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.321909
MYOG myogenin (myogenic factor 4) 0.315003
PDGFB platelet-derived growth factor beta polypeptide 0.309204
LIG1 ligase I, DNA, ATP-dependent 0.307757
NEFL neurofilament, light polypeptide 0.307757
MAN2C1 mannosidase, alpha, class 2C, member 1 0.30631
AXL AXL receptor tyrosine kinase 0.30631
PRKCE protein kinase C, epsilon 0.301615
PROM1 prominin 1 0.299452
PRKCQ protein kinase C, theta 0.293694
LHX2 LIM homeobox 2 0.292975
PGLS 6-phosphogluconolactonase 0.287952
RTN1 reticulon 1 0.287235
SIVA1 SIVA1, apoptosis-inducing factor 0.286519
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.285086
GJA1 gap junction protein, alpha 1, 43kDa 0.285086
CCDC6 coiled-coil domain containing 6 0.284728
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.284728
ANXA8 annexin A8 0.284371
CARD17 caspase recruitment domain family, member 17 0.284013
EML4 echinoderm microtubule associated protein like 4 0.284013
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 0.282225
FRK fyn-related Src family tyrosine kinase 0.281868
CETN2 centrin, EF-hand protein, 2 0.273308
BCL6 B-cell CLL/lymphoma 6 0.268687
L1CAM L1 cell adhesion molecule 0.264785
DAAM1 dishevelled associated activator of morphogenesis 1 0.259124
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.258417
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.257005
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.255946
HSF2 heat shock transcription factor 2 0.255594
MAGEA1 melanoma antigen family A1 0.254183
COL8A1 collagen, type VIII, alpha 1 0.253479
MYH11 myosin, heavy chain 11, smooth muscle 0.25207
DIAPH1 diaphanous-related formin 1 0.251366
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.251366
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.24715
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.24715
KIRREL kin of IRRE like (Drosophila) 0.243995
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.242245
SS18 synovial sarcoma translocation, chromosome 18 0.241546
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.239101
FLT1 fms-related tyrosine kinase 1 0.237357
CD9 CD9 molecule 0.235616
FZD8 frizzled class receptor 8 0.23353
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.232489
CTHRC1 collagen triple helix repeat containing 1 0.232489
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.230409
STAT1 signal transducer and activator of transcription 1, 91kDa 0.22937
MIR222 microRNA 222 0.227297
SPRY4 sprouty homolog 4 (Drosophila) 0.225229
IGF1 insulin-like growth factor 1 (somatomedin C) 0.224884
PACRG PARK2 co-regulated 0.219398
CLDN2 claudin 2 0.219057
CCNB1 cyclin B1 0.216332
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.210253
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.208245
CLDN1 claudin 1 0.205585
GRAP2 GRB2-related adaptor protein 2 0.204923
BRS3 bombesin-like receptor 3 0.198386
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.19742
NELL1 NEL-like 1 (chicken) 0.190168
S100P S100 calcium binding protein P 0.188022
ALB albumin 0.186811
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.18591
MEN1 multiple endocrine neoplasia I 0.184128
LIG4 ligase IV, DNA, ATP-dependent 0.182666
VIM vimentin 0.182375
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.182375
PKM pyruvate kinase, muscle 0.17896
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 0.177301
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.176485
AMT aminomethyltransferase 0.175679
AMY1C amylase, alpha 1C (salivary) 0.173057
AMY1B amylase, alpha 1B (salivary) 0.173057
AMY1A amylase, alpha 1A (salivary) 0.173057
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.172544
SST somatostatin 0.172291
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.172038
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.171785
BPIFA1 BPI fold containing family A, member 1 0.171785
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.169571
PARP2 poly (ADP-ribose) polymerase 2 0.168381
GIPC1 GIPC PDZ domain containing family, member 1 0.167915
ZNF135 zinc finger protein 135 0.167452
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.166995
RANBP2 RAN binding protein 2 0.163729
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.163729
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.162908
SHD Src homology 2 domain containing transforming protein D 0.161523
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.160948
SH3GL1 SH3-domain GRB2-like 1 0.160948
PRMT5 protein arginine methyltransferase 5 0.158097