ganciclovir-6289 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ganciclovir-6289 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AFF4 AF4/FMR2 family, member 4
ALAD aminolevulinate dehydratase
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX12 arachidonate 12-lipoxygenase
ANAPC5 anaphase promoting complex subunit 5
BTN3A2 butyrophilin, subfamily 3, member A2
C19ORF60 chromosome 19 open reading frame 60
C9ORF156 chromosome 9 open reading frame 156
CA5B carbonic anhydrase VB, mitochondrial
CALD1 caldesmon 1
CCR2 chemokine (C-C motif) receptor 2
CD58 CD58 molecule
CDK20 cyclin-dependent kinase 20
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLCN4 chloride channel, voltage-sensitive 4
CLEC11A C-type lectin domain family 11, member A
CNR2 cannabinoid receptor 2 (macrophage)
COX4I1 cytochrome c oxidase subunit IV isoform 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CXCR6 chemokine (C-X-C motif) receptor 6
DCAF11 DDB1 and CUL4 associated factor 11
DENND2A DENN/MADD domain containing 2A
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DZIP1 DAZ interacting zinc finger protein 1
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPAS1 endothelial PAS domain protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
ETV1 ets variant 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FYB FYN binding protein
GALK2 galactokinase 2
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GAS8 growth arrest-specific 8
HESX1 HESX homeobox 1
HMG20B high mobility group 20B
HSDL2 hydroxysteroid dehydrogenase like 2
ITPKA inositol-trisphosphate 3-kinase A
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCTD13 potassium channel tetramerization domain containing 13
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT9 keratin 9, type I
LAT2 linker for activation of T cells family, member 2
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MAP2K7 mitogen-activated protein kinase kinase 7
MAU2 MAU2 sister chromatid cohesion factor
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD6 major facilitator superfamily domain containing 6
MTCP1 mature T-cell proliferation 1
MX1 MX dynamin-like GTPase 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYLIP myosin regulatory light chain interacting protein
NPAS3 neuronal PAS domain protein 3
NRP1 neuropilin 1
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE8B phosphodiesterase 8B
PDPK1 3-phosphoinositide dependent protein kinase 1
POU2F2 POU class 2 homeobox 2
PTK7 protein tyrosine kinase 7 (inactive)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB26 RAB26, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP3 RAN binding protein 3
RARG retinoic acid receptor, gamma
RHOT2 ras homolog family member T2
RRAGB Ras-related GTP binding B
RYK receptor-like tyrosine kinase
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SIX2 SIX homeobox 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SPON1 spondin 1, extracellular matrix protein
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRSF1 serine/arginine-rich splicing factor 1
SSH3 slingshot protein phosphatase 3
STAT2 signal transducer and activator of transcription 2, 113kDa
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TACR1 tachykinin receptor 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D30 TBC1 domain family, member 30
TBC1D5 TBC1 domain family, member 5
TBXAS1 thromboxane A synthase 1 (platelet)
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM25 tripartite motif containing 25
USP34 ubiquitin specific peptidase 34
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF528 zinc finger protein 528
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABLIM3 actin binding LIM protein family, member 3
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADGRG2 adhesion G protein-coupled receptor G2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1RL complement component 1, r subcomponent-like
CCDC85C coiled-coil domain containing 85C
CENPO centromere protein O
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CINP cyclin-dependent kinase 2 interacting protein
CLDN7 claudin 7
CLSPN claspin
CPA4 carboxypeptidase A4
CTAGE9 CTAGE family, member 9
DCAF17 DDB1 and CUL4 associated factor 17
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DSPP dentin sialophosphoprotein
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPPK1 epiplakin 1
EVL Enah/Vasp-like
F3 coagulation factor III (thromboplastin, tissue factor)
FAM102A family with sequence similarity 102, member A
FAM131A family with sequence similarity 131, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGGY FGGY carbohydrate kinase domain containing
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRAMD4 GRAM domain containing 4
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HIST1H3B histone cluster 1, H3b
HMOX1 heme oxygenase 1
HOOK2 hook microtubule-tethering protein 2
HOXC4 homeobox C4
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IDI2-AS1 IDI2 antisense RNA 1
IGFLR1 IGF-like family receptor 1
IL24 interleukin 24
INF2 inverted formin, FH2 and WH2 domain containing
IRF6 interferon regulatory factor 6
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
MCOLN1 mucolipin 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MOXD1 monooxygenase, DBH-like 1
MXRA8 matrix-remodelling associated 8
NOL6 nucleolar protein 6 (RNA-associated)
OCLN occludin
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P3H1 prolyl 3-hydroxylase 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFRL platelet-derived growth factor receptor-like
PDIA3 protein disulfide isomerase family A, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PISD phosphatidylserine decarboxylase
PMCH pro-melanin-concentrating hormone
PRPH peripherin
PRR3 proline rich 3
PSKH1 protein serine kinase H1
PTGES2 prostaglandin E synthase 2
RARS arginyl-tRNA synthetase
RIC8B RIC8 guanine nucleotide exchange factor B
RPAP2 RNA polymerase II associated protein 2
SETBP1 SET binding protein 1
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIK1 salt-inducible kinase 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM242 transmembrane protein 242
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPCN1 two pore segment channel 1
TRAPPC6A trafficking protein particle complex 6A
UBAC1 UBA domain containing 1
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
VASH2 vasohibin 2
VEGFB vascular endothelial growth factor B
WDR41 WD repeat domain 41
ZDHHC18 zinc finger, DHHC-type containing 18
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF629 zinc finger protein 629