ganciclovir-5389 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ganciclovir-5389 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALS2CL ALS2 C-terminal like
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAHCC1 BAH domain and coiled-coil containing 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP5 bone morphogenetic protein 5
C11ORF63 chromosome 11 open reading frame 63
C15ORF39 chromosome 15 open reading frame 39
C18ORF25 chromosome 18 open reading frame 25
CASC1 cancer susceptibility candidate 1
CCL22 chemokine (C-C motif) ligand 22
CCNK cyclin K
CD80 CD80 molecule
CEP41 centrosomal protein 41kDa
CFHR4 complement factor H-related 4
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CRP C-reactive protein, pentraxin-related
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DMPK dystrophia myotonica-protein kinase
DOCK5 dedicator of cytokinesis 5
DOCK9 dedicator of cytokinesis 9
DOK4 docking protein 4
DRD2 dopamine receptor D2
DTNA dystrobrevin, alpha
E2F4 E2F transcription factor 4, p107/p130-binding
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EHD1 EH-domain containing 1
EN2 engrailed homeobox 2
F12 coagulation factor XII (Hageman factor)
FFAR2 free fatty acid receptor 2
FGF5 fibroblast growth factor 5
FLOT1 flotillin 1
FPR1 formyl peptide receptor 1
FSCN1 fascin actin-bundling protein 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLCE glucuronic acid epimerase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GM2A GM2 ganglioside activator
GPR21 G protein-coupled receptor 21
HBEGF heparin-binding EGF-like growth factor
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFFO1 intermediate filament family orphan 1
IL11 interleukin 11
JMJD4 jumonji domain containing 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4B lysine (K)-specific demethylase 4B
KLF6 Kruppel-like factor 6
LAT2 linker for activation of T cells family, member 2
LEPR leptin receptor
LGALS4 lectin, galactoside-binding, soluble, 4
LOC79999 uncharacterized LOC79999
LTBP4 latent transforming growth factor beta binding protein 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MCTP1 multiple C2 domains, transmembrane 1
MED16 mediator complex subunit 16
MIER2 mesoderm induction early response 1, family member 2
MKL1 megakaryoblastic leukemia (translocation) 1
MPZ myelin protein zero
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NPR3 natriuretic peptide receptor 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PPP5C protein phosphatase 5, catalytic subunit
PRRC2B proline-rich coiled-coil 2B
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RB1 retinoblastoma 1
RPH3AL rabphilin 3A-like (without C2 domains)
SENP7 SUMO1/sentrin specific peptidase 7
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIPA1 signal-induced proliferation-associated 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STAT2 signal transducer and activator of transcription 2, 113kDa
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYT5 synaptotagmin V
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR2 toll-like receptor 2
TP53I11 tumor protein p53 inducible protein 11
TRIM15 tripartite motif containing 15
TUBB1 tubulin, beta 1 class VI
WDR59 WD repeat domain 59
WIZ widely interspaced zinc finger motifs
ZNF324 zinc finger protein 324
ZNF419 zinc finger protein 419
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTL8 actin-like 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
ALPK1 alpha-kinase 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARMC4 armadillo repeat containing 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BMP4 bone morphogenetic protein 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BST2 bone marrow stromal cell antigen 2
C11ORF30 chromosome 11 open reading frame 30
C9ORF9 chromosome 9 open reading frame 9
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC9 coiled-coil domain containing 9
CD79B CD79b molecule, immunoglobulin-associated beta
CDK3 cyclin-dependent kinase 3
CENPO centromere protein O
CEP131 centrosomal protein 131kDa
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CRY2 cryptochrome circadian clock 2
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTSV cathepsin V
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIXDC1 DIX domain containing 1
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FAM110B family with sequence similarity 110, member B
FBXO22 F-box protein 22
FCHO1 FCH domain only 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FRK fyn-related Src family tyrosine kinase
GJA9 gap junction protein, alpha 9, 59kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HOXC5 homeobox C5
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
INO80D INO80 complex subunit D
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IQCG IQ motif containing G
IRAK4 interleukin-1 receptor-associated kinase 4
IRF9 interferon regulatory factor 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL36 kelch-like family member 36
LAMP3 lysosomal-associated membrane protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPS18C mitochondrial ribosomal protein S18C
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NDOR1 NADPH dependent diflavin oxidoreductase 1
ONECUT2 one cut homeobox 2
PDE12 phosphodiesterase 12
PILRB paired immunoglobin-like type 2 receptor beta
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PRSS16 protease, serine, 16 (thymus)
PTDSS2 phosphatidylserine synthase 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIN2 Ras and Rab interactor 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA2L spermatogenesis associated 2-like
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TESC tescalcin
TET3 tet methylcytosine dioxygenase 3
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM104 transmembrane protein 104
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
ZBTB44 zinc finger and BTB domain containing 44
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZNF134 zinc finger protein 134
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF574 zinc finger protein 574