gallbladder disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A gastrointestinal system disease that is located_in the gallbladder. (Human Disease Ontology, DOID_0060262)
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Genes

329 genes co-occuring with the disease gallbladder disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CCK cholecystokinin 2.42583
ALPPL2 alkaline phosphatase, placental-like 2 1.90428
ALPP alkaline phosphatase, placental 1.90335
ALPL alkaline phosphatase, liver/bone/kidney 1.90288
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.72228
ELOVL6 ELOVL fatty acid elongase 6 1.5014
SST somatostatin 1.43859
GGT1 gamma-glutamyltransferase 1 1.29658
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.2944
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.21738
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.18798
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.17335
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.16692
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.16692
GUSB glucuronidase, beta 1.1439
CRP C-reactive protein, pentraxin-related 1.12741
ECRP ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene 1.04588
SOBP sine oculis binding protein homolog (Drosophila) 1.03872
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 1.02187
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.01638
ALB albumin 0.946186
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.94577
F2 coagulation factor II (thrombin) 0.926692
GAST gastrin 0.890078
HSF4 heat shock transcription factor 4 0.875738
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.870825
TDH L-threonine dehydrogenase (pseudogene) 0.841344
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.805257
S100A9 S100 calcium binding protein A9 0.800744
GGT2 gamma-glutamyltransferase 2 0.783116
STK10 serine/threonine kinase 10 0.772479
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 0.770435
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.761047
INS insulin 0.756156
CCKAR cholecystokinin A receptor 0.733001
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.689893
GLYCAM1 glycosylation dependent cell adhesion molecule 1 (pseudogene) 0.67312
TP53 tumor protein p53 0.671925
PDPN podoplanin 0.669936
PPY pancreatic polypeptide 0.650508
CUTA cutA divalent cation tolerance homolog (E. coli) 0.637495
PNLIPRP1 pancreatic lipase-related protein 1 0.635921
MARS2 methionyl-tRNA synthetase 2, mitochondrial 0.635135
PER1 period circadian clock 1 0.635135
SIK3 SIK family kinase 3 0.629635
GCG glucagon 0.604591
MLN motilin 0.59952
LEP leptin 0.590558
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.574605
IGF1 insulin-like growth factor 1 (somatomedin C) 0.574217
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.565666
PER2 period circadian clock 2 0.559839
FGD5 FYVE, RhoGEF and PH domain containing 5 0.55945
VMAC vimentin-type intermediate filament associated coiled-coil protein 0.548583
F3 coagulation factor III (thromboplastin, tissue factor) 0.545093
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.544705
SLC51B solute carrier family 51, beta subunit 0.54393
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.52729
SCN2A sodium channel, voltage gated, type II alpha subunit 0.52729
CD79A CD79a molecule, immunoglobulin-associated alpha 0.525746
LPA lipoprotein, Lp(a) 0.51919
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.51919
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.506123
LYZ lysozyme 0.504973
FBL fibrillarin 0.498467
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.496557
PLA2G1B phospholipase A2, group IB (pancreas) 0.491597
PGRMC1 progesterone receptor membrane component 1 0.489691
KRT7 keratin 7, type II 0.484744
SEC23B Sec23 homolog B (S. cerevisiae) 0.482844
MUC2 mucin 2, oligomeric mucus/gel-forming 0.482084
ZNF135 zinc finger protein 135 0.479427
APOB apolipoprotein B 0.474498
CELA3B chymotrypsin-like elastase family, member 3B 0.470711
HP haptoglobin 0.464283
PLEK2 pleckstrin 2 0.459373
HPR haptoglobin-related protein 0.458241
FBLL1 fibrillarin-like 1 0.442795
PTGIS prostaglandin I2 (prostacyclin) synthase 0.439034
TES testin LIM domain protein 0.431519
NTS neurotensin 0.42364
HBB hemoglobin, beta 0.416896
CTSC cathepsin C 0.416147
GRAP GRB2-related adaptor protein 0.406798
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.405305
DUSP8 dual specificity phosphatase 8 0.404557
KRAS Kirsten rat sarcoma viral oncogene homolog 0.40008
F12 coagulation factor XII (Hageman factor) 0.398962
CTRB1 chymotrypsinogen B1 0.398216
CP ceruloplasmin (ferroxidase) 0.39598
NCR3 natural cytotoxicity triggering receptor 3 0.395235
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.393374
MUC6 mucin 6, oligomeric mucus/gel-forming 0.391141
AFP alpha-fetoprotein 0.390769
EFS embryonal Fyn-associated substrate 0.388166
SPINK1 serine peptidase inhibitor, Kazal type 1 0.377031
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.377031
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.368518
VIP vasoactive intestinal peptide 0.368149
KRT20 keratin 20, type I 0.360395
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.359289
ELANE elastase, neutrophil expressed 0.35892
FHL1 four and a half LIM domains 1 0.346777
CHD1L chromodomain helicase DNA binding protein 1-like 0.346409
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.346409
CELA1 chymotrypsin-like elastase family, member 1 0.345675
NASP nuclear autoantigenic sperm protein (histone-binding) 0.341639
HIST1H1D histone cluster 1, H1d 0.340539
FCGBP Fc fragment of IgG binding protein 0.337242
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.32701
IL6 interleukin 6 0.324094
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.321545
TPGS2 tubulin polyglutamylase complex subunit 2 0.320454
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.317909
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.317182
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.316819
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.316092
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.315003
TTC39A tetratricopeptide repeat domain 39A 0.314278
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.313915
GPR35 G protein-coupled receptor 35 0.312827
HBD hemoglobin, delta 0.311377
HRAS Harvey rat sarcoma viral oncogene homolog 0.309204
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.308118
REG1B regenerating islet-derived 1 beta 0.306672
OLFML3 olfactomedin-like 3 0.306672
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.30631
SLCO1A2 solute carrier organic anion transporter family, member 1A2 0.302698
C6ORF25 chromosome 6 open reading frame 25 0.302337
FGF19 fibroblast growth factor 19 0.298011
FBXO8 F-box protein 8 0.296931
HHAT hedgehog acyltransferase 0.294413
APOE apolipoprotein E 0.289386
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.289386
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.285086
CD34 CD34 molecule 0.284371
CD93 CD93 molecule 0.281153
FECH ferrochelatase 0.280439
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.279724
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.277584
PPARA peroxisome proliferator-activated receptor alpha 0.271886
TF transferrin 0.270819
DAPK1 death-associated protein kinase 1 0.266558
THAP3 THAP domain containing, apoptosis associated protein 3 0.266558
SNN stannin 0.260891
ZNF79 zinc finger protein 79 0.260184
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.257711
PAAF1 proteasomal ATPase-associated factor 1 0.256299
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.254183
TTR transthyretin 0.250311
CD4 CD4 molecule 0.242945
FLNA filamin A, alpha 0.242595
UVRAG UV radiation resistance associated 0.242245
CAT catalase 0.240847
CHGA chromogranin A 0.237706
TECR trans-2,3-enoyl-CoA reductase 0.225917
CHRM3 cholinergic receptor, muscarinic 3 0.222822
KNG1 kininogen 1 0.219057
ERP29 endoplasmic reticulum protein 29 0.215992
PSCA prostate stem cell antigen 0.210925
MSI1 musashi RNA-binding protein 1 0.208579
REG4 regenerating islet-derived family, member 4 0.207245
FTH1 ferritin, heavy polypeptide 1 0.203933
FTL ferritin, light polypeptide 0.203933
FABP6 fatty acid binding protein 6, ileal 0.203275
ACPP acid phosphatase, prostate 0.198064
CD68 CD68 molecule 0.195501
SSTR5 somatostatin receptor 5 0.191097
SQLE squalene epoxidase 0.189244
ADGRL4 adhesion G protein-coupled receptor L4 0.188632
SLC51A solute carrier family 51, alpha subunit 0.183835
PKM pyruvate kinase, muscle 0.183835
MPO myeloperoxidase 0.18151
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.18151
MMP23B matrix metallopeptidase 23B 0.17896
CDKN2A cyclin-dependent kinase inhibitor 2A 0.176757
APOA2 apolipoprotein A-II 0.175679
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.173571
IL1B interleukin 1, beta 0.170299
RHCE Rh blood group, CcEe antigens 0.169571
TUBGCP4 tubulin, gamma complex associated protein 4 0.169091
FBN2 fibrillin 2 0.167682
MUC1 mucin 1, cell surface associated 0.165655
ASMT acetylserotonin O-methyltransferase 0.165001
HBA2 hemoglobin, alpha 2 0.164786
MLH1 mutL homolog 1 0.164359
LACTB lactamase, beta 0.163523
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.160203
SCTR secretin receptor 0.159302
KRT81 keratin 81, type II 0.141652
DKKL1 dickkopf-like 1 0.136396
F10 coagulation factor X 0.135431
GBA glucosidase, beta, acid 0.133569
CTSB cathepsin B 0.133556
MSR1 macrophage scavenger receptor 1 0.133169
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.129666
CXCR6 chemokine (C-X-C motif) receptor 6 0.129522
TRIM37 tripartite motif containing 37 0.12927
DUT deoxyuridine triphosphatase 0.128029
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.12687
CXCL16 chemokine (C-X-C motif) ligand 16 0.126388
MUC3A mucin 3A, cell surface associated 0.125964
HOPX HOP homeobox 0.125529
SSTR4 somatostatin receptor 4 0.122766
DLD dihydrolipoamide dehydrogenase 0.120939
CLDN1 claudin 1 0.120126
CLDN7 claudin 7 0.118794
RBMS1 RNA binding motif, single stranded interacting protein 1 0.116832
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.115853
SSTR1 somatostatin receptor 1 0.115142
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.114792
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.114413
RPL5 ribosomal protein L5 0.112897
PGM1 phosphoglucomutase 1 0.111519
SAA2 serum amyloid A2 0.111173
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.110745
DCLK1 doublecortin-like kinase 1 0.110644
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.109067
ASXL1 additional sex combs like transcriptional regulator 1 0.10904
PNLIP pancreatic lipase 0.10861
SSTR2 somatostatin receptor 2 0.107715
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.104875
REG1A regenerating islet-derived 1 alpha 0.104638
PRDX5 peroxiredoxin 5 0.10422
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.103164
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.102366
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.10221
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.102084
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.101896
MDK midkine (neurite growth-promoting factor 2) 0.101834
GH1 growth hormone 1 0.101395
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.101109
TARP TCR gamma alternate reading frame protein 0.100853
LY96 lymphocyte antigen 96 0.100276
MEMO1 mediator of cell motility 1 0.099493
HAL histidine ammonia-lyase 0.099264
CD63 CD63 molecule 0.098936
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.098936
MATK megakaryocyte-associated tyrosine kinase 0.098335
MTTP microsomal triglyceride transfer protein 0.098
LCT lactase 0.097866
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.097732
THRSP thyroid hormone responsive 0.097258
PGF placental growth factor 0.097018
IRF6 interferon regulatory factor 6 0.096402
ACTA1 actin, alpha 1, skeletal muscle 0.096162
DMRTA1 DMRT-like family A1 0.096057
UST uronyl-2-sulfotransferase 0.096022
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.095777
MIXL1 Mix paired-like homeobox 0.095672
PKLR pyruvate kinase, liver and RBC 0.095672
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.095602
POMP proteasome maturation protein 0.095392
ESPN espin 0.095357
MYBPC1 myosin binding protein C, slow type 0.095218
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.094973
AANAT aralkylamine N-acetyltransferase 0.094904
LCAT lecithin-cholesterol acyltransferase 0.094619
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.094405
AURKAIP1 aurora kinase A interacting protein 1 0.094085
LTF lactotransferrin 0.093907
LARS leucyl-tRNA synthetase 0.0938
HDGF hepatoma-derived growth factor 0.093764
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.093443
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.092898
CTRC chymotrypsin C (caldecrin) 0.092789
NT5C 5', 3'-nucleotidase, cytosolic 0.09268
APOC3 apolipoprotein C-III 0.092318
CRAT carnitine O-acetyltransferase 0.092063
PIDD1 p53-induced death domain protein 1 0.091878
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.09125
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.091176
ANXA3 annexin A3 0.091139
EPHA7 EPH receptor A7 0.091102
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.091028
HOXB4 homeobox B4 0.090881
SHF Src homology 2 domain containing F 0.090621
BECN1 beclin 1, autophagy related 0.090508
CGA glycoprotein hormones, alpha polypeptide 0.090358
NPC1L1 NPC1-like 1 0.090358
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.090057
FKBP4 FK506 binding protein 4, 59kDa 0.089606
UBIAD1 UbiA prenyltransferase domain containing 1 0.089231
SAA1 serum amyloid A1 0.089039
GDF9 growth differentiation factor 9 0.088963
CSN1S1 casein alpha s1 0.088848
RUNX3 runt-related transcription factor 3 0.08881
LIG3 ligase III, DNA, ATP-dependent 0.088657
PPT1 palmitoyl-protein thioesterase 1 0.088428
CD274 CD274 molecule 0.088275
SORD sorbitol dehydrogenase 0.088161
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.088085
ALOX5 arachidonate 5-lipoxygenase 0.08797
FLAD1 flavin adenine dinucleotide synthetase 1 0.08797
RHD Rh blood group, D antigen 0.087856
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.087585
PEG10 paternally expressed 10 0.08743
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 0.087391
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.087275
HBA1 hemoglobin, alpha 1 0.086887
ERAS ES cell expressed Ras 0.086693
CD59 CD59 molecule, complement regulatory protein 0.086577
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.086577
LEPR leptin receptor 0.086228
TSG101 tumor susceptibility 101 0.08611
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.085873
APOLD1 apolipoprotein L domain containing 1 0.085873
TPRG1L tumor protein p63 regulated 1-like 0.085677
PCNT pericentrin 0.085559
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.085441
VIPR1 vasoactive intestinal peptide receptor 1 0.085126
TOB1 transducer of ERBB2, 1 0.085048
S100A8 S100 calcium binding protein A8 0.085008
CYS1 cystin 1 0.084613
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.084493
ACTA2 actin, alpha 2, smooth muscle, aorta 0.084095
TXN thioredoxin 0.083736
HAX1 HCLS1 associated protein X-1 0.083656
CPE carboxypeptidase E 0.083577
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.083298
MAP9 microtubule-associated protein 9 0.082895
S100A10 S100 calcium binding protein A10 0.082814
TLR4 toll-like receptor 4 0.082774
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.081886
EPCAM epithelial cell adhesion molecule 0.081886
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.081806
PTH parathyroid hormone 0.081357
CDC6 cell division cycle 6 0.081194
ACOT13 acyl-CoA thioesterase 13 0.081072