gait complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. (Gene Ontology, GO_0097452)
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19 proteins co-occuring with the gait complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EPRS glutamyl-prolyl-tRNA synthetase 2.40257
MRPL13 mitochondrial ribosomal protein L13 1.90285
RPL13A ribosomal protein L13a 1.83883
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.31951
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.12909
CP ceruloplasmin (ferroxidase) 1.08882
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.925604
VEGFA vascular endothelial growth factor A 0.83781
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.769083
DAPK3 death-associated protein kinase 3 0.750452
DAPK1 death-associated protein kinase 1 0.688576
DAP death-associated protein 0.632878
ILF3 interleukin enhancer binding factor 3, 90kDa 0.625206
RRM1 ribonucleotide reductase M1 0.541117
CDK5 cyclin-dependent kinase 5 0.490944
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.455613
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.30924
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.225622
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.208481