|Dataset||COMPARTMENTS Curated Protein Localization Evidence Scores|
|Category||structural or functional annotations|
|Description||A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. (Gene Ontology, GO_0097452)|
|Downloads & Tools|
4 proteins localized to the gait complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.