gait complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. (Gene Ontology, GO_0097452)
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4 proteins localized to the gait complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.663342
EPRS glutamyl-prolyl-tRNA synthetase 0.663342
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.663342
RPL13A ribosomal protein L13a 0.663342