furaltadone-3932 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the furaltadone-3932 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACO2 aconitase 2, mitochondrial
ADD2 adducin 2 (beta)
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ALOX5 arachidonate 5-lipoxygenase
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP1 Rho GTPase activating protein 1
ART1 ADP-ribosyltransferase 1
ATP11A ATPase, class VI, type 11A
BDKRB2 bradykinin receptor B2
C1ORF95 chromosome 1 open reading frame 95
C4BPA complement component 4 binding protein, alpha
C7ORF69 chromosome 7 open reading frame 69
CD70 CD70 molecule
CD8A CD8a molecule
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN18 claudin 18
CLEC3B C-type lectin domain family 3, member B
COL16A1 collagen, type XVI, alpha 1
CRH corticotropin releasing hormone
CSHL1 chorionic somatomammotropin hormone-like 1
CTIF CBP80/20-dependent translation initiation factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAZL deleted in azoospermia-like
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
EFS embryonal Fyn-associated substrate
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
ETV1 ets variant 1
EYA4 EYA transcriptional coactivator and phosphatase 4
F13B coagulation factor XIII, B polypeptide
FABP7 fatty acid binding protein 7, brain
FAM163A family with sequence similarity 163, member A
FCMR Fc fragment of IgM receptor
FLJ11292
FN1 fibronectin 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXYD5 FXYD domain containing ion transport regulator 5
GAP43 growth associated protein 43
GFAP glial fibrillary acidic protein
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GP6 glycoprotein VI (platelet)
GPATCH4 G patch domain containing 4
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR15 G protein-coupled receptor 15
GPR63 G protein-coupled receptor 63
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAL histidine ammonia-lyase
HDAC7 histone deacetylase 7
HIST1H3I histone cluster 1, H3i
HOXB2 homeobox B2
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IGLJ3 immunoglobulin lambda joining 3
IL27RA interleukin 27 receptor, alpha
KIF25 kinesin family member 25
KLK3 kallikrein-related peptidase 3
LECT1 leukocyte cell derived chemotaxin 1
LHX2 LIM homeobox 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MCM3AP minichromosome maintenance complex component 3 associated protein
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR4A3 nuclear receptor subfamily 4, group A, member 3
OXCT2 3-oxoacid CoA transferase 2
PAGE1 P antigen family, member 1 (prostate associated)
PARVB parvin, beta
PCDHB6 protocadherin beta 6
PLCH1 phospholipase C, eta 1
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
RBMS2 RNA binding motif, single stranded interacting protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RORC RAR-related orphan receptor C
SAFB scaffold attachment factor B
SCN1A sodium channel, voltage gated, type I alpha subunit
SFTPB surfactant protein B
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPRY4 sprouty homolog 4 (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
STOML1 stomatin (EPB72)-like 1
T T, brachyury homolog (mouse)
TEX14 testis expressed 14
TREM2 triggering receptor expressed on myeloid cells 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WNT2B wingless-type MMTV integration site family, member 2B
ZBTB17 zinc finger and BTB domain containing 17
ZNF154 zinc finger protein 154
ZNF280A zinc finger protein 280A
ZNF460 zinc finger protein 460

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD17B abhydrolase domain containing 17B
ACTL8 actin-like 8
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ATAT1 alpha tubulin acetyltransferase 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B9D2 B9 protein domain 2
BAHCC1 BAH domain and coiled-coil containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C2ORF27A chromosome 2 open reading frame 27A
C5AR2 complement component 5a receptor 2
C9ORF9 chromosome 9 open reading frame 9
CASD1 CAS1 domain containing 1
CCDC132 coiled-coil domain containing 132
CDK3 cyclin-dependent kinase 3
CEP72 centrosomal protein 72kDa
CGA glycoprotein hormones, alpha polypeptide
CHM choroideremia (Rab escort protein 1)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNTFR ciliary neurotrophic factor receptor
CSF1R colony stimulating factor 1 receptor
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FAAH fatty acid amide hydrolase
FBXL7 F-box and leucine-rich repeat protein 7
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXI1 forkhead box I1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR143 G protein-coupled receptor 143
GRPR gastrin-releasing peptide receptor
HIST1H1D histone cluster 1, H1d
HIST1H3F histone cluster 1, H3f
HOXC5 homeobox C5
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI6 interferon, alpha-inducible protein 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPO8 importin 8
KDM7A lysine (K)-specific demethylase 7A
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
KLHL28 kelch-like family member 28
KREMEN2 kringle containing transmembrane protein 2
KRT83 keratin 83, type II
LMTK2 lemur tyrosine kinase 2
LRRC61 leucine rich repeat containing 61
LTBP2 latent transforming growth factor beta binding protein 2
MCOLN1 mucolipin 1
METTL16 methyltransferase like 16
MFGE8 milk fat globule-EGF factor 8 protein
MOB3B MOB kinase activator 3B
NPFFR1 neuropeptide FF receptor 1
NUP62CL nucleoporin 62kDa C-terminal like
NXPE3 neurexophilin and PC-esterase domain family, member 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSMR oncostatin M receptor
PAX9 paired box 9
PDE12 phosphodiesterase 12
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPRM protein tyrosine phosphatase, receptor type, M
PYHIN1 pyrin and HIN domain family, member 1
QPCT glutaminyl-peptide cyclotransferase
RFXAP regulatory factor X-associated protein
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1B small proline-rich protein 1B
TBC1D19 TBC1 domain family, member 19
TET3 tet methylcytosine dioxygenase 3
TM4SF4 transmembrane 4 L six family member 4
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN9 tetraspanin 9
TTLL1 tubulin tyrosine ligase-like family member 1
VASH2 vasohibin 2
VIM vimentin
ZBTB25 zinc finger and BTB domain containing 25
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF41 zinc finger protein 41