forming Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

373 genes co-occuring with the biological term forming in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIP aryl hydrocarbon receptor interacting protein
AIRE autoimmune regulator
AKAP5 A kinase (PRKA) anchor protein 5
ANGPTL2 angiopoietin-like 2
ANXA2 annexin A2
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP5B1 adaptor-related protein complex 5, beta 1 subunit
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATAD3A ATPase family, AAA domain containing 3A
ATAD3B ATPase family, AAA domain containing 3B
ATF2 activating transcription factor 2
ATG9A autophagy related 9A
ATPIF1 ATPase inhibitory factor 1
AURKA aurora kinase A
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BAIAP2 BAI1-associated protein 2
BAK1 BCL2-antagonist/killer 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC3 baculoviral IAP repeat containing 3
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BTF3 basic transcription factor 3
C8A complement component 8, alpha polypeptide
CADM1 cell adhesion molecule 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX2 chromobox homolog 2
CBX5 chromobox homolog 5
CC2D1A coiled-coil and C2 domain containing 1A
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CDA cytidine deaminase
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDYL chromodomain protein, Y-like
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CENPA centromere protein A
CEP55 centrosomal protein 55kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD4 chromodomain helicase DNA binding protein 4
CHMP4B charged multivesicular body protein 4B
CHPT1 choline phosphotransferase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLDN5 claudin 5
CLIC1 chloride intracellular channel 1
CNR1 cannabinoid receptor 1 (brain)
COX17 COX17 cytochrome c oxidase copper chaperone
CRACR2A calcium release activated channel regulator 2A
CRYAB crystallin, alpha B
CRYBB2 crystallin, beta B2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSG cathepsin G
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DCAF6 DDB1 and CUL4 associated factor 6
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT3 DNA-damage-inducible transcript 3
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DES desmin
DHPS deoxyhypusine synthase
DIAPH1 diaphanous-related formin 1
DLG1 discs, large homolog 1 (Drosophila)
E2F1 E2F transcription factor 1
EBF2 early B-cell factor 2
EGFR epidermal growth factor receptor
EMILIN2 elastin microfibril interfacer 2
EPHB4 EPH receptor B4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F13B coagulation factor XIII, B polypeptide
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FANCA Fanconi anemia, complementation group A
FANCG Fanconi anemia, complementation group G
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FKBP5 FK506 binding protein 5
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FNBP1 formin binding protein 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FURIN furin (paired basic amino acid cleaving enzyme)
FXYD1 FXYD domain containing ion transport regulator 1
G6PC glucose-6-phosphatase, catalytic subunit
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GBP1 guanylate binding protein 1, interferon-inducible
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJA8 gap junction protein, alpha 8, 50kDa
GJB2 gap junction protein, beta 2, 26kDa
GJC1 gap junction protein, gamma 1, 45kDa
GJC2 gap junction protein, gamma 2, 47kDa
GLI1 GLI family zinc finger 1
GPHA2 glycoprotein hormone alpha 2
GRN granulin
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
HBB hemoglobin, beta
HCCAT5 hepatocellular carcinoma associated transcript 5 (non-protein coding)
HCRTR1 hypocretin (orexin) receptor 1
HCRTR2 hypocretin (orexin) receptor 2
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H2AC histone cluster 2, H2ac
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HOXA9 homeobox A9
HP haptoglobin
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IAPP islet amyloid polypeptide
ICAM3 intercellular adhesion molecule 3
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL17A interleukin 17A
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL37 interleukin 37
INHBA inhibin, beta A
INSIG1 insulin induced gene 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAG1 jagged 1
JAK1 Janus kinase 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK3 kallikrein-related peptidase 3
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT13 keratin 13, type I
KRT7 keratin 7, type II
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LMBRD1 LMBR1 domain containing 1
LONP1 lon peptidase 1, mitochondrial
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MED28 mediator complex subunit 28
MET MET proto-oncogene, receptor tyrosine kinase
MICB MHC class I polypeptide-related sequence B
MIR1228 microRNA 1228
MIR196B microRNA 196b
MIR21 microRNA 21
MIR34A microRNA 34a
MLANA melan-A
MLEC malectin
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MSTN myostatin
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NEB nebulin
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFIA nuclear factor I/A
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NOD1 nucleotide-binding oligomerization domain containing 1
NODAL nodal growth differentiation factor
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUPR1 nuclear protein, transcriptional regulator, 1
OPHN1 oligophrenin 1
PARK7 parkinson protein 7
PAWR PRKC, apoptosis, WT1, regulator
PDCD10 programmed cell death 10
PDGFB platelet-derived growth factor beta polypeptide
PDZK1 PDZ domain containing 1
PELP1 proline, glutamate and leucine rich protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKP1 plakophilin 1
PKP3 plakophilin 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
POLG polymerase (DNA directed), gamma
PRDM2 PR domain containing 2, with ZNF domain
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRMT7 protein arginine methyltransferase 7
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROM1 prominin 1
PRPH peripherin
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGIS prostaglandin I2 (prostacyclin) synthase
PTH1R parathyroid hormone 1 receptor
PTK2 protein tyrosine kinase 2
PTMA prothymosin, alpha
PURA purine-rich element binding protein A
QKI QKI, KH domain containing, RNA binding
RAB34 RAB34, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
REG3A regenerating islet-derived 3 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RILP Rab interacting lysosomal protein
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPA1 replication protein A1, 70kDa
RPN1 ribophorin I
RPS16 ribosomal protein S16
RPS7 ribosomal protein S7
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
RYR3 ryanodine receptor 3
S100A6 S100 calcium binding protein A6
SCO1 SCO1 cytochrome c oxidase assembly protein
SCT secretin
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SIN3A SIN3 transcription regulator family member A
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMN2 survival of motor neuron 2, centromeric
SNAI1 snail family zinc finger 1
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX18 sorting nexin 18
SOD1 superoxide dismutase 1, soluble
SOX9 SRY (sex determining region Y)-box 9
SP7 Sp7 transcription factor
SPG11 spastic paraplegia 11 (autosomal recessive)
SPTA1 spectrin, alpha, erythrocytic 1
SQSTM1 sequestosome 1
SRP72 signal recognition particle 72kDa
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX1A syntaxin 1A (brain)
STYK1 serine/threonine/tyrosine kinase 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TARDBP TAR DNA binding protein
TAS2R1 taste receptor, type 2, member 1
TDGF1 teratocarcinoma-derived growth factor 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TGM2 transglutaminase 2
THBD thrombomodulin
TLR2 toll-like receptor 2
TMEM30A transmembrane protein 30A
TMEM55B transmembrane protein 55B
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNNT2 troponin T type 2 (cardiac)
TNPO1 transportin 1
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TPR translocated promoter region, nuclear basket protein
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM13 tripartite motif containing 13
TRIM27 tripartite motif containing 27
TRIM5 tripartite motif containing 5
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTR transthyretin
TUBB1 tubulin, beta 1 class VI
TUBB2B tubulin, beta 2B class IIb
TUBB4B tubulin, beta 4B class IVb
TXNRD1 thioredoxin reductase 1
UBC ubiquitin C
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBN1 ubinuclein 1
UBQLN1 ubiquilin 1
UBQLN2 ubiquilin 2
UNC119 unc-119 homolog (C. elegans)
UNG uracil-DNA glycosylase
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VPRBP Vpr (HIV-1) binding protein
VWF von Willebrand factor
WASF1 WAS protein family, member 1
WDR83 WD repeat domain 83
WNT1 wingless-type MMTV integration site family, member 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
YY1 YY1 transcription factor
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZFYVE26 zinc finger, FYVE domain containing 26