focal segmental glomerulosclerosis Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Segmental accumulation of scar tissue in individual (but not all) glomeruli. (Human Phenotype Ontology, HP_0000097)
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19 genes associated with the focal segmental glomerulosclerosis phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ACTN4 actinin, alpha 4
APOL1 apolipoprotein L, 1
CD2AP CD2-associated protein
CLCN5 chloride channel, voltage-sensitive 5
COQ6 coenzyme Q6 monooxygenase
G6PC glucose-6-phosphatase, catalytic subunit
INF2 inverted formin, FH2 and WH2 domain containing
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
MYO1E myosin IE
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
PAX2 paired box 2
PLCE1 phospholipase C, epsilon 1
PTPRO protein tyrosine phosphatase, receptor type, O
REN renin
SCARB2 scavenger receptor class B, member 2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
WT1 Wilms tumor 1