focal hepatic necrosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description morphological changes resulting from one or more localized areas of pathological death of some or all liver tissue; usually due to irreversible damage (Mammalian Phenotype Ontology, MP_0001656)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001656
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Genes

11 gene mutations causing the focal hepatic necrosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
C3 complement component 3
C5AR2 complement component 5a receptor 2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGA fibrinogen alpha chain
IGFBP1 insulin-like growth factor binding protein 1
NF1 neurofibromin 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
PROC protein C (inactivator of coagulation factors Va and VIIIa)
SPTA1 spectrin, alpha, erythrocytic 1
TLR4 toll-like receptor 4