flutamide-4539 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the flutamide-4539 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADARB1 adenosine deaminase, RNA-specific, B1
AIM1L absent in melanoma 1-like
AKR1C4 aldo-keto reductase family 1, member C4
ANGPTL4 angiopoietin-like 4
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATXN2L ataxin 2-like
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D2 B9 protein domain 2
BMP2 bone morphogenetic protein 2
BMP8B bone morphogenetic protein 8b
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTG2 BTG family, member 2
CATSPERB catsper channel auxiliary subunit beta
CD58 CD58 molecule
CDH19 cadherin 19, type 2
CDK6 cyclin-dependent kinase 6
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNGA1 cyclic nucleotide gated channel alpha 1
CNTN5 contactin 5
COL10A1 collagen, type X, alpha 1
CST1 cystatin SN
CXCR2 chemokine (C-X-C motif) receptor 2
DLX4 distal-less homeobox 4
DST dystonin
DTNB dystrobrevin, beta
DUOX1 dual oxidase 1
EDRF1 erythroid differentiation regulatory factor 1
EFNA5 ephrin-A5
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ETV1 ets variant 1
FAM135A family with sequence similarity 135, member A
FRMD8 FERM domain containing 8
FYB FYN binding protein
GAS7 growth arrest-specific 7
GK glycerol kinase
HDAC11 histone deacetylase 11
HEMK1 HemK methyltransferase family member 1
HIST1H4F histone cluster 1, H4f
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
IDS iduronate 2-sulfatase
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF5C kinesin family member 5C
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRP1 low density lipoprotein receptor-related protein 1
MARK2 MAP/microtubule affinity-regulating kinase 2
METTL7A methyltransferase like 7A
MLXIP MLX interacting protein
MTUS1 microtubule associated tumor suppressor 1
MUC4 mucin 4, cell surface associated
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NRF1 nuclear respiratory factor 1
NRP2 neuropilin 2
NYNRIN NYN domain and retroviral integrase containing
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PCDH12 protocadherin 12
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM7 PDZ and LIM domain 7 (enigma)
PECAM1 platelet/endothelial cell adhesion molecule 1
PLD1 phospholipase D1, phosphatidylcholine-specific
POU2F2 POU class 2 homeobox 2
PROX1 prospero homeobox 1
PTPRB protein tyrosine phosphatase, receptor type, B
PURG purine-rich element binding protein G
RB1 retinoblastoma 1
RCE1 Ras converting CAAX endopeptidase 1
RGS11 regulator of G-protein signaling 11
SLC25A30 solute carrier family 25, member 30
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMAD5 SMAD family member 5
SPIDR scaffolding protein involved in DNA repair
SPTB spectrin, beta, erythrocytic
STMN4 stathmin-like 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D30 TBC1 domain family, member 30
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCP10L t-complex 10-like
TCP11L1 t-complex 11, testis-specific-like 1
TFEC transcription factor EC
TGFB2 transforming growth factor, beta 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53I11 tumor protein p53 inducible protein 11
TPD52L1 tumor protein D52-like 1
TRGV5 T cell receptor gamma variable 5
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TUBA4B tubulin, alpha 4b
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
VPREB1 pre-B lymphocyte 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZEB1 zinc finger E-box binding homeobox 1
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADGRG2 adhesion G protein-coupled receptor G2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BAAT bile acid CoA:amino acid N-acyltransferase
BTF3P12 basic transcription factor 3 pseudogene 12
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CCDC106 coiled-coil domain containing 106
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CES3 carboxylesterase 3
CORO1A coronin, actin binding protein, 1A
CPED1 cadherin-like and PC-esterase domain containing 1
CREB5 cAMP responsive element binding protein 5
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL9 cullin 9
DLL3 delta-like 3 (Drosophila)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHA4 EPH receptor A4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM168B family with sequence similarity 168, member B
FAM184A family with sequence similarity 184, member A
FANCC Fanconi anemia, complementation group C
FOXN2 forkhead box N2
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AK histone cluster 1, H2ak
HOXA7 homeobox A7
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IQSEC2 IQ motif and Sec7 domain 2
KRT86 keratin 86, type II
LOC390998 ribosomal protein L10 pseudogene
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MECR mitochondrial trans-2-enoyl-CoA reductase
MED9 mediator complex subunit 9
MGP matrix Gla protein
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MNX1 motor neuron and pancreas homeobox 1
MON1B MON1 secretory trafficking family member B
MOSPD3 motile sperm domain containing 3
MTA2 metastasis associated 1 family, member 2
MX1 MX dynamin-like GTPase 1
MYO1F myosin IF
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRTN neurturin
NXPH4 neurexophilin 4
OLFML3 olfactomedin-like 3
OSR2 odd-skipped related transciption factor 2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRSS8 protease, serine, 8
PTK7 protein tyrosine kinase 7 (inactive)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RPAP1 RNA polymerase II associated protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD2A RWD domain containing 2A
S100A3 S100 calcium binding protein A3
SCAMP5 secretory carrier membrane protein 5
SCGB2A2 secretoglobin, family 2A, member 2
SERGEF secretion regulating guanine nucleotide exchange factor
SKA1 spindle and kinetochore associated complex subunit 1
SLMO1 slowmo homolog 1 (Drosophila)
SPEG SPEG complex locus
STARD3 StAR-related lipid transfer (START) domain containing 3
TBC1D17 TBC1 domain family, member 17
TCTN1 tectonic family member 1
THAP7 THAP domain containing 7
TMEM53 transmembrane protein 53
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSC22D4 TSC22 domain family, member 4
TSSC4 tumor suppressing subtransferable candidate 4
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
ZBTB22 zinc finger and BTB domain containing 22
ZFP30 ZFP30 zinc finger protein
ZNF253 zinc finger protein 253
ZNF358 zinc finger protein 358
ZNF37BP zinc finger protein 37B, pseudogene
ZNF408 zinc finger protein 408
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747