fluorocurarine-6219 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the fluorocurarine-6219 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AHNAK2 AHNAK nucleoprotein 2
AKR1C1 aldo-keto reductase family 1, member C1
ANKRD12 ankyrin repeat domain 12
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARFRP1 ADP-ribosylation factor related protein 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP2K BMP2 inducible kinase
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTN2A1 butyrophilin, subfamily 2, member A1
CDADC1 cytidine and dCMP deaminase domain containing 1
CLMN calmin (calponin-like, transmembrane)
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPD carboxypeptidase D
CYHR1 cysteine/histidine-rich 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DHODH dihydroorotate dehydrogenase (quinone)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ERAP1 endoplasmic reticulum aminopeptidase 1
ERC2-IT1 ERC2 intronic transcript 1
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
FGF6 fibroblast growth factor 6
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GON4L gon-4-like (C. elegans)
GRTP1 growth hormone regulated TBC protein 1
GTPBP4 GTP binding protein 4
HLA-G major histocompatibility complex, class I, G
HLA-J major histocompatibility complex, class I, J (pseudogene)
HPS1 Hermansky-Pudlak syndrome 1
IFITM1 interferon induced transmembrane protein 1
IGLV4-60 immunoglobulin lambda variable 4-60
INHBA inhibin, beta A
IRF9 interferon regulatory factor 9
JRK Jrk homolog (mouse)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KDM6B lysine (K)-specific demethylase 6B
KDM8 lysine (K)-specific demethylase 8
KRIT1 KRIT1, ankyrin repeat containing
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIG3 ligase III, DNA, ATP-dependent
LRRC14 leucine rich repeat containing 14
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBD3 methyl-CpG binding domain protein 3
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NAT6 N-acetyltransferase 6 (GCN5-related)
NF1 neurofibromin 1
NFE2L3 nuclear factor, erythroid 2-like 3
NOTCH2 notch 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB1 protocadherin beta 1
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
RAB6A RAB6A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
REEP1 receptor accessory protein 1
RETN resistin
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNASEH2B ribonuclease H2, subunit B
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RNFT2 ring finger protein, transmembrane 2
RREB1 ras responsive element binding protein 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SMC1A structural maintenance of chromosomes 1A
SND1-IT1 SND1 intronic transcript 1
SSPN sarcospan
STYK1 serine/threonine/tyrosine kinase 1
SUGP1 SURP and G patch domain containing 1
SYNC syncoilin, intermediate filament protein
SYNGR1 synaptogyrin 1
TBX10 T-box 10
TEF thyrotrophic embryonic factor
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM259 transmembrane protein 259
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBTB7A zinc finger and BTB domain containing 7A
ZFP30 ZFP30 zinc finger protein
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AEN apoptosis enhancing nuclease
ANKRD40 ankyrin repeat domain 40
ARHGAP5 Rho GTPase activating protein 5
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC6 armadillo repeat containing 6
ARMCX1 armadillo repeat containing, X-linked 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BRPF1 bromodomain and PHD finger containing, 1
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF88 chromosome 10 open reading frame 88
C22ORF29 chromosome 22 open reading frame 29
C5 complement component 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CFD complement factor D (adipsin)
CISH cytokine inducible SH2-containing protein
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNPY3 canopy FGF signaling regulator 3
COL4A5 collagen, type IV, alpha 5
CTNNBIP1 catenin, beta interacting protein 1
CXORF56 chromosome X open reading frame 56
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUSP12 dual specificity phosphatase 12
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FIP1L1 factor interacting with PAPOLA and CPSF1
FPGS folylpolyglutamate synthase
GMEB1 glucocorticoid modulatory element binding protein 1
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HP1BP3 heterochromatin protein 1, binding protein 3
INO80D INO80 complex subunit D
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KIFC1 kinesin family member C1
KLHL2 kelch-like family member 2
KRBOX4 KRAB box domain containing 4
KRT13 keratin 13, type I
LMNB1 lamin B1
LOXL1 lysyl oxidase-like 1
LRP5L low density lipoprotein receptor-related protein 5-like
LYPLA2P1 lysophospholipase II pseudogene 1
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
METTL2B methyltransferase like 2B
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
MYH9 myosin, heavy chain 9, non-muscle
NCS1 neuronal calcium sensor 1
NINL ninein-like
NT5C 5', 3'-nucleotidase, cytosolic
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PAQR6 progestin and adipoQ receptor family member VI
PARP16 poly (ADP-ribose) polymerase family, member 16
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G10 phospholipase A2, group X
PSKH1 protein serine kinase H1
PTPRU protein tyrosine phosphatase, receptor type, U
PUS3 pseudouridylate synthase 3
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS17 regulator of G-protein signaling 17
RNF126P1 ring finger protein 126 pseudogene 1
RNF25 ring finger protein 25
RNF31 ring finger protein 31
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SH3GL1 SH3-domain GRB2-like 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SPATA7 spermatogenesis associated 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN2 tectonic family member 2
THOP1 thimet oligopeptidase 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TKFC triokinase/FMN cyclase
TMC7 transmembrane channel-like 7
TRAIP TRAF interacting protein
XYLT2 xylosyltransferase II
ZC3H12A zinc finger CCCH-type containing 12A
ZNF14 zinc finger protein 14
ZNF180 zinc finger protein 180
ZNF248 zinc finger protein 248
ZNF280D zinc finger protein 280D
ZNF574 zinc finger protein 574
ZNF623 zinc finger protein 623