flufenamic acid-316 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the flufenamic acid-316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANK1 ankyrin 1, erythrocytic
APOLD1 apolipoprotein L domain containing 1
BAIAP3 BAI1-associated protein 3
BIN1 bridging integrator 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CALCA calcitonin-related polypeptide alpha
CAMKV CaM kinase-like vesicle-associated
CCDC70 coiled-coil domain containing 70
CCDC87 coiled-coil domain containing 87
CDC25C cell division cycle 25C
CDCP1 CUB domain containing protein 1
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CH25H cholesterol 25-hydroxylase
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CLDN17 claudin 17
CMKLR1 chemerin chemokine-like receptor 1
COL4A1 collagen, type IV, alpha 1
COL6A3 collagen, type VI, alpha 3
CST4 cystatin S
CYB5R2 cytochrome b5 reductase 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
EML2 echinoderm microtubule associated protein like 2
ESR1 estrogen receptor 1
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGFR4 fibroblast growth factor receptor 4
FTCD formimidoyltransferase cyclodeaminase
FXYD1 FXYD domain containing ion transport regulator 1
GAB1 GRB2-associated binding protein 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLG1 golgi glycoprotein 1
GPR4 G protein-coupled receptor 4
HBD hemoglobin, delta
HBE1 hemoglobin, epsilon 1
HPX hemopexin
HRH1 histamine receptor H1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFI6 interferon, alpha-inducible protein 6
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KDM5D lysine (K)-specific demethylase 5D
KIF25-AS1 KIF25 antisense RNA 1
KLHL1 kelch-like family member 1
KLK12 kallikrein-related peptidase 12
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT6A keratin 6A, type II
LIAS lipoic acid synthetase
LINC00652 long intergenic non-protein coding RNA 652
LOC441601 septin 7 pseudogene
MAOA monoamine oxidase A
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MASP2 mannan-binding lectin serine peptidase 2
MCHR1 melanin-concentrating hormone receptor 1
MOCS1 molybdenum cofactor synthesis 1
MTNR1A melatonin receptor 1A
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NCKAP1L NCK-associated protein 1-like
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPAT nuclear protein, ataxia-telangiectasia locus
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXF2 nuclear RNA export factor 2
PAX1 paired box 1
PDE4DIP phosphodiesterase 4D interacting protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRT protein tyrosine phosphatase, receptor type, T
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RALBP1 ralA binding protein 1
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIMS1 regulating synaptic membrane exocytosis 1
RND2 Rho family GTPase 2
RRAGD Ras-related GTP binding D
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPRY2 sprouty homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STOML1 stomatin (EPB72)-like 1
STX2 syntaxin 2
SYN1 synapsin I
TBCD tubulin folding cofactor D
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNK1 tyrosine kinase, non-receptor, 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
VIPR2 vasoactive intestinal peptide receptor 2
WIZ widely interspaced zinc finger motifs
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF460 zinc finger protein 460
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
ACVRL1 activin A receptor type II-like 1
ALX3 ALX homeobox 3
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
AURKC aurora kinase C
C3ORF18 chromosome 3 open reading frame 18
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC121 coiled-coil domain containing 121
CCDC132 coiled-coil domain containing 132
CD38 CD38 molecule
COPZ2 coatomer protein complex, subunit zeta 2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYSLTR2 cysteinyl leukotriene receptor 2
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKD diacylglycerol kinase, delta 130kDa
DRP2 dystrophin related protein 2
DUSP13 dual specificity phosphatase 13
FGF16 fibroblast growth factor 16
FGFBP1 fibroblast growth factor binding protein 1
FOLR2 folate receptor 2 (fetal)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GPR19 G protein-coupled receptor 19
GREB1L growth regulation by estrogen in breast cancer-like
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
H2AFY2 H2A histone family, member Y2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IHH indian hedgehog
ITGA8 integrin, alpha 8
ITPKB inositol-trisphosphate 3-kinase B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNIP2 Kv channel interacting protein 2
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KDM8 lysine (K)-specific demethylase 8
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLF2 Kruppel-like factor 2
KLHDC8A kelch domain containing 8A
KLHL3 kelch-like family member 3
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LGALS9 lectin, galactoside-binding, soluble, 9
LIN7A lin-7 homolog A (C. elegans)
MFSD12 major facilitator superfamily domain containing 12
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MLXIPL MLX interacting protein-like
MYBPH myosin binding protein H
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYO1F myosin IF
NAT6 N-acetyltransferase 6 (GCN5-related)
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPY4R neuropeptide Y receptor Y4
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PFAS phosphoribosylformylglycinamidine synthase
PGS1 phosphatidylglycerophosphate synthase 1
PKD2L1 polycystic kidney disease 2-like 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRMT7 protein arginine methyltransferase 7
PRSS2 protease, serine, 2 (trypsin 2)
PYCRL pyrroline-5-carboxylate reductase-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAVER2 ribonucleoprotein, PTB-binding 2
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RFPL2 ret finger protein-like 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRAGB Ras-related GTP binding B
SDC3 syndecan 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC44A4 solute carrier family 44, member 4
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPP2 secreted phosphoprotein 2, 24kDa
STARD8 StAR-related lipid transfer (START) domain containing 8
SYT2 synaptotagmin II
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNN tenascin N
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSPAN32 tetraspanin 32
TTR transthyretin
UMOD uromodulin
UNC93B1 unc-93 homolog B1 (C. elegans)
ZBED2 zinc finger, BED-type containing 2
ZFR2 zinc finger RNA binding protein 2
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF211 zinc finger protein 211