filtration diaphragm Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. (Gene Ontology, GO_0036056)
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Genes

98 proteins co-occuring with the filtration diaphragm cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 4.02697
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 3.33369
CD2AP CD2-associated protein 2.81054
KIRREL kin of IRRE like (Drosophila) 2.50994
ACTN4 actinin, alpha 4 1.68604
SYNPO synaptopodin 1.61236
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.57131
TJP1 tight junction protein 1 1.40354
KIRREL2 kin of IRRE like 2 (Drosophila) 1.33087
LMX1B LIM homeobox transcription factor 1, beta 1.29585
KIRREL3 kin of IRRE like 3 (Drosophila) 1.28997
DDN dendrin 1.27239
WT1 Wilms tumor 1 1.17517
IGSF5 immunoglobulin superfamily, member 5 1.1148
SOX12 SRY (sex determining region Y)-box 12 1.05842
ALB albumin 1.03479
WTIP Wilms tumor 1 interacting protein 1.02729
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 0.998086
FYN FYN proto-oncogene, Src family tyrosine kinase 0.899499
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.879633
SH2D4A SH2 domain containing 4A 0.849746
LRP2 low density lipoprotein receptor-related protein 2 0.834138
PLCE1 phospholipase C, epsilon 1 0.726152
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 0.711022
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.697784
ACE angiotensin I converting enzyme 0.692955
STOM stomatin 0.679849
PODXL podocalyxin-like 0.676368
EFNB1 ephrin-B1 0.636723
PLXNA1 plexin A1 0.606128
RARA retinoic acid receptor, alpha 0.591392
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.572162
FAT1 FAT atypical cadherin 1 0.550599
SH2D5 SH2 domain containing 5 0.523885
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.512047
KCTD7 potassium channel tetramerization domain containing 7 0.500258
ARL4C ADP-ribosylation factor-like 4C 0.485693
VEGFA vascular endothelial growth factor A 0.485289
SDK1 sidekick cell adhesion molecule 1 0.484886
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.47844
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.476831
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.475625
CMIP c-Maf inducing protein 0.472813
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.464397
IQGAP1 IQ motif containing GTPase activating protein 1 0.445275
VASH1 vasohibin 1 0.416902
ILK integrin-linked kinase 0.403637
CLIC5 chloride intracellular channel 5 0.401304
MYH9 myosin, heavy chain 9, non-muscle 0.399751
SV2B synaptic vesicle glycoprotein 2B 0.383895
TCF21 transcription factor 21 0.383509
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.372366
ZHX1 zinc fingers and homeoboxes 1 0.366623
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.366241
CTTN cortactin 0.341907
VANGL2 VANGL planar cell polarity protein 2 0.340017
ABRA actin binding Rho activating protein 0.339639
RBBP7 retinoblastoma binding protein 7 0.319702
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.317456
PARD6A par-6 family cell polarity regulator alpha 0.316334
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.308122
CTSL cathepsin L 0.304399
EZR ezrin 0.298455
AMOTL1 angiomotin like 1 0.297713
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.292527
PLA2R1 phospholipase A2 receptor 1, 180kDa 0.278509
COX6C cytochrome c oxidase subunit VIc 0.273
STS steroid sulfatase (microsomal), isozyme S 0.272267
PLXNA2 plexin A2 0.2719
CXADR coxsackie virus and adenovirus receptor 0.2708
PICK1 protein interacting with PRKCA 1 0.265311
S100A4 S100 calcium binding protein A4 0.26385
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.261296
EHD3 EH-domain containing 3 0.254017
MYO1E myosin IE 0.247492
TNS2 tensin 2 0.245685
MYO1C myosin IC 0.240996
XPR1 xenotropic and polytropic retrovirus receptor 1 0.239197
THY1 Thy-1 cell surface antigen 0.23776
COL4A5 collagen, type IV, alpha 5 0.236324
TGFB1 transforming growth factor, beta 1 0.233817
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.231672
CFL1 cofilin 1 (non-muscle) 0.231672
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 0.219617
SRA1 steroid receptor RNA activator 1 0.21716
CLDN6 claudin 6 0.213669
SOX11 SRY (sex determining region Y)-box 11 0.211587
CTNND1 catenin (cadherin-associated protein), delta 1 0.207451
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.202009
LRRC7 leucine rich repeat containing 7 0.199993
INF2 inverted formin, FH2 and WH2 domain containing 0.18859
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.181524
IFITM2 interferon induced transmembrane protein 2 0.179167
SOX4 SRY (sex determining region Y)-box 4 0.169859
MAF1 MAF1 homolog (S. cerevisiae) 0.159856
LAMB2 laminin, beta 2 (laminin S) 0.158882
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.158692
PHB prohibitin 0.158315