female reproductive organ cancer Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva. (Human Disease Ontology, DOID_120)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:120
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Genes

153 genes associated with the disease female reproductive organ cancer in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.46498
HNF1B HNF1 homeobox B 0.842681
BABAM1 BRISC and BRCA1 A complex member 1 0.561648
HAGLR HOXD antisense growth-associated long non-coding RNA 0.55156
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.504579
INTS2 integrator complex subunit 2 0.489011
BNC2 basonuclin 2 0.4838
NSF N-ethylmaleimide-sensitive factor 0.47241
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.464734
EXOC1 exocyst complex component 1 0.464387
SKAP1 src kinase associated phosphoprotein 1 0.464387
CHMP4C charged multivesicular body protein 4C 0.459601
SNTG1 syntrophin, gamma 1 0.453572
MED13 mediator complex subunit 13 0.441593
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.432325
ANKLE1 ankyrin repeat and LEM domain containing 1 0.41791
GRIK1 glutamate receptor, ionotropic, kainate 1 0.41233
FGD5 FYVE, RhoGEF and PH domain containing 5 0.409349
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.405247
DCT dopachrome tautomerase 0.403458
CLINT1 clathrin interactor 1 0.400309
CDH13 cadherin 13 0.400044
PTPRD protein tyrosine phosphatase, receptor type, D 0.398423
SLX4 SLX4 structure-specific endonuclease subunit 0.397192
FHIT fragile histidine triad 0.397024
PDE11A phosphodiesterase 11A 0.391749
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.391492
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.389604
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.388858
NRG1 neuregulin 1 0.38489
LOC643623 uncharacterized LOC643623 0.382752
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.382537
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.382117
ZNF607 zinc finger protein 607 0.38151
SHISA9 shisa family member 9 0.380068
ADGRL2 adhesion G protein-coupled receptor L2 0.379091
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.366972
USP10 ubiquitin specific peptidase 10 0.366972
KAT2B K(lysine) acetyltransferase 2B 0.364717
ADAM12 ADAM metallopeptidase domain 12 0.362774
LINC00189 long intergenic non-protein coding RNA 189 0.362774
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.362774
LINGO2 leucine rich repeat and Ig domain containing 2 0.361067
DCC DCC netrin 1 receptor 0.361067
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.359837
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.358706
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.358174
OGFRL1 opioid growth factor receptor-like 1 0.35624
FRMD8 FERM domain containing 8 0.355986
CPED1 cadherin-like and PC-esterase domain containing 1 0.354894
TTC23 tetratricopeptide repeat domain 23 0.354777
PCSK6 proprotein convertase subtilisin/kexin type 6 0.353124
IQSEC3 IQ motif and Sec7 domain 3 0.351351
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.351074
MAN1B1 mannosidase, alpha, class 1B, member 1 0.348867
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.348554
SHROOM3 shroom family member 3 0.348477
LOC146513 uncharacterized LOC146513 0.348477
ZMYND15 zinc finger, MYND-type containing 15 0.34758
TTYH1 tweety family member 1 0.345997
LOC100507195 uncharacterized LOC100507195 0.345738
BTNL2 butyrophilin-like 2 0.343698
HLA-B major histocompatibility complex, class I, B 0.343148
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 0.342564
DOCK1 dedicator of cytokinesis 1 0.341719
CLIP3 CAP-GLY domain containing linker protein 3 0.340701
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.340213
SCARB1 scavenger receptor class B, member 1 0.337961
PTPRO protein tyrosine phosphatase, receptor type, O 0.336606
PAQR5 progestin and adipoQ receptor family member V 0.33652
GPA33 glycoprotein A33 (transmembrane) 0.336477
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.335883
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 0.335431
SP100 SP100 nuclear antigen 0.33519
GTSF1 gametocyte specific factor 1 0.333992
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.333733
RNLS renalase, FAD-dependent amine oxidase 0.333514
CNBD1 cyclic nucleotide binding domain containing 1 0.333441
FAM13A family with sequence similarity 13, member A 0.333333
DPH6 diphthamine biosynthesis 6 0.333119
FOXP1 forkhead box P1 0.332053
MRPL23 mitochondrial ribosomal protein L23 0.332053
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.33202
PRLR prolactin receptor 0.331561
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.331272
PPA2 pyrophosphatase (inorganic) 2 0.329432
DLG2 discs, large homolog 2 (Drosophila) 0.327086
PARK2 parkin RBR E3 ubiquitin protein ligase 0.326863
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.326814
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.326692
PITPNM3 PITPNM family member 3 0.326619
FGFR2 fibroblast growth factor receptor 2 0.326331
DOCK5 dedicator of cytokinesis 5 0.326284
CDH23 cadherin-related 23 0.325978
LRP1 low density lipoprotein receptor-related protein 1 0.3257
DGKI diacylglycerol kinase, iota 0.32545
TMEM222 transmembrane protein 222 0.325359
NRG3 neuregulin 3 0.32526
CEP128 centrosomal protein 128kDa 0.324948
DSCAML1 Down syndrome cell adhesion molecule like 1 0.32449
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.324043
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.323945
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.323678
AADACL3 arylacetamide deacetylase-like 3 0.323486
ARID1A AT rich interactive domain 1A (SWI-like) 0.322599
INSC inscuteable homolog (Drosophila) 0.322327
LOXHD1 lipoxygenase homology domains 1 0.321948
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.321904
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.321619
SLIT3 slit homolog 3 (Drosophila) 0.321468
MROH2A maestro heat-like repeat family member 2A 0.321382
RAI1 retinoic acid induced 1 0.321297
LOC100287010 uncharacterized LOC100287010 0.321105
MTUS1 microtubule associated tumor suppressor 1 0.320958
ADGRB3 adhesion G protein-coupled receptor B3 0.320937
SASH1 SAM and SH3 domain containing 1 0.320502
ONECUT2 one cut homeobox 2 0.320339
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.320117
NDFIP1 Nedd4 family interacting protein 1 0.318206
XRN1 5'-3' exoribonuclease 1 0.316634
BBS12 Bardet-Biedl syndrome 12 0.316137
GSTO1 glutathione S-transferase omega 1 0.315653
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.312299
NELFE negative elongation factor complex member E 0.306473
TMPRSS4 transmembrane protease, serine 4 0.306033
SH2D7 SH2 domain containing 7 0.301372
CETN4P centrin EF-hand protein 4, pseudogene 0.300251
PCSK2 proprotein convertase subtilisin/kexin type 2 0.293877
CGN cingulin 0.290169
SPPL2A signal peptide peptidase like 2A 0.286601
VWDE von Willebrand factor D and EGF domains 0.285923
CDYL2 chromodomain protein, Y-like 2 0.285406
PALLD palladin, cytoskeletal associated protein 0.283816
CTIF CBP80/20-dependent translation initiation factor 0.283444
KCTD16 potassium channel tetramerization domain containing 16 0.282412
FOXN3 forkhead box N3 0.279629
CDHR3 cadherin-related family member 3 0.279448
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.278955
EGFR epidermal growth factor receptor 0.276826
FYN FYN proto-oncogene, Src family tyrosine kinase 0.274859
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.274334
CTNND2 catenin (cadherin-associated protein), delta 2 0.273422
TTC12 tetratricopeptide repeat domain 12 0.273172
HEATR1 HEAT repeat containing 1 0.273101
RIC1 RAB6A GEF complex partner 1 0.272925
LOC100287225 uncharacterized LOC100287225 0.271824
GAS2 growth arrest-specific 2 0.27179
FANCL Fanconi anemia, complementation group L 0.270995
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.270256
PEX1 peroxisomal biogenesis factor 1 0.268868
NFYC nuclear transcription factor Y, gamma 0.267552
GLRA3 glycine receptor, alpha 3 0.266382
MAPK4 mitogen-activated protein kinase 4 0.266301