fatal Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

118 genes co-occuring with the biological term fatal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE2 angiotensin I converting enzyme 2
ADSL adenylosuccinate lyase
AGER advanced glycosylation end product-specific receptor
ALK anaplastic lymphoma receptor tyrosine kinase
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APOC1 apolipoprotein C-I
APP amyloid beta (A4) precursor protein
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BCL2 B-cell CLL/lymphoma 2
BOLA3 bolA family member 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD163 CD163 molecule
CD27 CD27 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD46 CD46 molecule, complement regulatory protein
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCN7 chloride channel, voltage-sensitive 7
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CRP C-reactive protein, pentraxin-related
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DICER1 dicer 1, ribonuclease type III
DPYD dihydropyrimidine dehydrogenase
DSG1 desmoglein 1
DSG3 desmoglein 3
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FHL1 four and a half LIM domains 1
GBA glucosidase, beta, acid
GSN gelsolin
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL15RA interleukin 15 receptor, alpha
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
ITK IL2-inducible T-cell kinase
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LIPA lipase A, lysosomal acid, cholesterol esterase
LTF lactotransferrin
MBL2 mannose-binding lectin (protein C) 2, soluble
MECOM MDS1 and EVI1 complex locus
MFN2 mitofusin 2
MMP2 matrix metallopeptidase 2
MRPS22 mitochondrial ribosomal protein S22
MT-TS1 tRNA
MTDH metadherin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFU1 NFU1 iron-sulfur cluster scaffold
NPPB natriuretic peptide B
PARP1 poly (ADP-ribose) polymerase 1
POLG polymerase (DNA directed), gamma
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PSAP prosaposin
PSCA prostate stem cell antigen
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RYR2 ryanodine receptor 2 (cardiac)
SCN5A sodium channel, voltage gated, type V alpha subunit
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFTPB surfactant protein B
SIRT3 sirtuin 3
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SOST sclerostin
TARDBP TAR DNA binding protein
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TK2 thymidine kinase 2, mitochondrial
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNNC1 troponin C type 1 (slow)
TNNI3 troponin I type 3 (cardiac)
TPMT thiopurine S-methyltransferase
TPP1 tripeptidyl peptidase I
TTN titin
TTR transthyretin
TYMP thymidine phosphorylase
UNC13D unc-13 homolog D (C. elegans)
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor