fat Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

328 genes co-occuring with the biological term fat in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABRA actin binding Rho activating protein
ACACB acetyl-CoA carboxylase beta
ACADVL acyl-CoA dehydrogenase, very long chain
ACE angiotensin I converting enzyme
ACOT11 acyl-CoA thioesterase 11
ACP5 acid phosphatase 5, tartrate resistant
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALMS1 Alstrom syndrome protein 1
ALOX15 arachidonate 15-lipoxygenase
ANGPTL4 angiopoietin-like 4
AOC3 amine oxidase, copper containing 3
APLN apelin
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP7 aquaporin 7
AQP9 aquaporin 9
AR androgen receptor
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
AVP arginine vasopressin
AVPR1A arginine vasopressin receptor 1A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL10 B-cell CLL/lymphoma 10
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP2 bone morphogenetic protein 2
BMP6 bone morphogenetic protein 6
BRD8 bromodomain containing 8
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C19ORF80 chromosome 19 open reading frame 80
C3 complement component 3
CAPN10 calpain 10
CAV2 caveolin 2
CCAR2 cell cycle and apoptosis regulator 2
CCK cholecystokinin
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELA3B chymotrypsin-like elastase family, member 3B
CES1 carboxylesterase 1
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHUK conserved helix-loop-helix ubiquitous kinase
CIDEA cell death-inducing DFFA-like effector a
CKM creatine kinase, muscle
CLPS colipase, pancreatic
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CPE carboxypeptidase E
CPT1B carnitine palmitoyltransferase 1B (muscle)
CPT2 carnitine palmitoyltransferase 2
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CRY2 cryptochrome circadian clock 2
CTSK cathepsin K
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DGAT1 diacylglycerol O-acyltransferase 1
DGAT2 diacylglycerol O-acyltransferase 2
EDN1 endothelin 1
EGF epidermal growth factor
ENHO energy homeostasis associated
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EP400 E1A binding protein p400
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAAH fatty acid amide hydrolase
FABP1 fatty acid binding protein 1, liver
FABP2 fatty acid binding protein 2, intestinal
FABP3 fatty acid binding protein 3, muscle and heart
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FASN fatty acid synthase
FAT1 FAT atypical cadherin 1
FFAR1 free fatty acid receptor 1
FFAR4 free fatty acid receptor 4
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF19 fibroblast growth factor 19
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
FNDC5 fibronectin type III domain containing 5
FOXO1 forkhead box O1
FTO fat mass and obesity associated
GAL galanin/GMAP prepropeptide
GALR1 galanin receptor 1
GC group-specific component (vitamin D binding protein)
GCG glucagon
GCKR glucokinase (hexokinase 4) regulator
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPC4 glypican 4
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GPX1 glutathione peroxidase 1
GPX7 glutathione peroxidase 7
GRB14 growth factor receptor-bound protein 14
GSTK1 glutathione S-transferase kappa 1
H2AFZ H2A histone family, member Z
HADH hydroxyacyl-CoA dehydrogenase
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP1 insulin-like growth factor binding protein 1
IL10 interleukin 10
IL11 interleukin 11
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
IL6R interleukin 6 receptor
INS insulin
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ISL1 ISL LIM homeobox 1
KLF15 Kruppel-like factor 15
LDLR low density lipoprotein receptor
LEP leptin
LEPQTL1 Leptin, serum levels of
LEPR leptin receptor
LIPC lipase, hepatic
LIPE lipase, hormone-sensitive
LMNA lamin A/C
LNPEP leucyl/cystinyl aminopeptidase
LPIN1 lipin 1
LPIN2 lipin 2
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYPLAL1 lysophospholipase-like 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MEST mesoderm specific transcript
MFGE8 milk fat globule-EGF factor 8 protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR126 microRNA 126
MIR148A microRNA 148a
MIR217 microRNA 217
MIR93 microRNA 93
MMP9 matrix metallopeptidase 9
MOGAT2 monoacylglycerol O-acyltransferase 2
MPO myeloperoxidase
MSRA methionine sulfoxide reductase A
MSTN myostatin
MT2A metallothionein 2A
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1B melatonin receptor 1B
MTTP microsomal triglyceride transfer protein
NAMPT nicotinamide phosphoribosyltransferase
NFYC nuclear transcription factor Y, gamma
NLRP3 NLR family, pyrin domain containing 3
NNT nicotinamide nucleotide transhydrogenase
NOS3 nitric oxide synthase 3 (endothelial cell)
NPC2 Niemann-Pick disease, type C2
NPPB natriuretic peptide B
NPY neuropeptide Y
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C1P1 nuclear receptor subfamily 3, group C, member 1 pseudogene 1
NRIP1 nuclear receptor interacting protein 1
NT5C2 5'-nucleotidase, cytosolic II
NUCB2 nucleobindin 2
OPRM1 opioid receptor, mu 1
OXT oxytocin/neurophysin I prepropeptide
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLIN1 perilipin 1
PLIN2 perilipin 2
PLIN3 perilipin 3
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNLIPRP2 pancreatic lipase-related protein 2
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA3 patatin-like phospholipase domain containing 3
POMC proopiomelanocortin
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPY pancreatic polypeptide
PRDM16 PR domain containing 16
PRDX3 peroxiredoxin 3
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
PTEN phosphatase and tensin homolog
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTRF polymerase I and transcript release factor
PTX3 pentraxin 3, long
PYY peptide YY
QRFP pyroglutamylated RFamide peptide
RAI1 retinoic acid induced 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RETN resistin
RGS6 regulator of G-protein signaling 6
RIC3 RIC3 acetylcholine receptor chaperone
SAR1B secretion associated, Ras related GTPase 1B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCT secretin
SELE selectin E
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERTAD2 SERTA domain containing 2
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
SH2B1 SH2B adaptor protein 1
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SNRPN small nuclear ribonucleoprotein polypeptide N
SOCS3 suppressor of cytokine signaling 3
SOST sclerostin
SOX6 SRY (sex determining region Y)-box 6
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SREBF1 sterol regulatory element binding transcription factor 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
STAB1 stabilin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STS steroid sulfatase (microsomal), isozyme S
TACSTD2 tumor-associated calcium signal transducer 2
TARDBP TAR DNA binding protein
TBX15 T-box 15
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFA transforming growth factor, alpha
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TM6SF2 transmembrane 6 superfamily member 2
TMEM18 transmembrane protein 18
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRIB2 tribbles pseudokinase 2
UCN3 urocortin 3
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
USF1 upstream transcription factor 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT5B wingless-type MMTV integration site family, member 5B
ZFP36 ZFP36 ring finger protein
ZNRF3 zinc and ring finger 3