failure of eyelid fusion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description the upper and lower thin folds of skin and muscle that cover the exposed portion of the eye do not fuse together during development; normally fused by E17 in the mouse (Mammalian Phenotype Ontology, MP_0009264)
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17 gene mutations causing the failure of eyelid fusion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ALX3 ALX homeobox 3
APAF1 apoptotic peptidase activating factor 1
DSC1 desmocollin 1
EGFR epidermal growth factor receptor
JUN jun proto-oncogene
LIMK2 LIM domain kinase 2
LRP6 low density lipoprotein receptor-related protein 6
LUZP1 leucine zipper protein 1
NFIB nuclear factor I/B
OSR2 odd-skipped related transciption factor 2
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
SEC24B SEC24 family member B
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TGFA transforming growth factor, alpha
VANGL2 VANGL planar cell polarity protein 2