extrinsic allergic alveolitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss. (Human Disease Ontology, DOID_841)
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Genes

184 genes co-occuring with the disease extrinsic allergic alveolitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 1.76094
TNF tumor necrosis factor 1.33152
CD79A CD79a molecule, immunoglobulin-associated alpha 1.29964
FN1 fibronectin 1 1.29134
ALB albumin 1.19704
CYCS cytochrome c, somatic 1.13163
ACE angiotensin I converting enzyme 1.12698
TGFB1 transforming growth factor, beta 1 1.07236
MUC1 mucin 1, cell surface associated 0.95369
CXCL8 chemokine (C-X-C motif) ligand 8 0.939534
CCL3 chemokine (C-C motif) ligand 3 0.86059
IL2 interleukin 2 0.857315
B3GAT1 beta-1,3-glucuronyltransferase 1 0.804846
ZNF17 zinc finger protein 17 0.802795
CXCR3 chemokine (C-X-C motif) receptor 3 0.789262
IL2RA interleukin 2 receptor, alpha 0.776159
C5AR1 complement component 5a receptor 1 0.77575
SOD2 superoxide dismutase 2, mitochondrial 0.733811
MPO myeloperoxidase 0.721673
EAPP E2F-associated phosphoprotein 0.711587
CXCL10 chemokine (C-X-C motif) ligand 10 0.692296
ICAM1 intercellular adhesion molecule 1 0.691094
FLNC filamin C, gamma 0.688291
IL1B interleukin 1, beta 0.684692
LYZ lysozyme 0.683493
PI3 peptidase inhibitor 3, skin-derived 0.655254
HARS histidyl-tRNA synthetase 0.651298
CPM carboxypeptidase M 0.648533
CAPS calcyphosine 0.646953
IL6 interleukin 6 0.639857
ELANE elastase, neutrophil expressed 0.63907
BANF2 barrier to autointegration factor 2 0.624927
CCL2 chemokine (C-C motif) ligand 2 0.6214
IL1A interleukin 1, alpha 0.612401
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.611229
SELL selectin L 0.610448
GUSB glucuronidase, beta 0.604591
IRF5 interferon regulatory factor 5 0.59913
CEND1 cell cycle exit and neuronal differentiation 1 0.595623
SFTPD surfactant protein D 0.548583
LTV1 LTV1 ribosome biogenesis factor 0.548583
CD80 CD80 molecule 0.531154
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.527676
CD72 CD72 molecule 0.52729
MUC3A mucin 3A, cell surface associated 0.523816
RGS3 regulator of G-protein signaling 3 0.509576
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.501144
CD19 CD19 molecule 0.485505
PARP9 poly (ADP-ribose) polymerase family, member 9 0.483604
SLC35G5 solute carrier family 35, member G5 0.480566
CWC15 CWC15 spliceosome-associated protein 0.475634
RPL32 ribosomal protein L32 0.472225
IL4 interleukin 4 0.46466
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.462772
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.444676
PLG plasminogen 0.423265
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.416147
SLC38A4 solute carrier family 38, member 4 0.404184
CXCR2 chemokine (C-X-C motif) receptor 2 0.403811
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.401572
CTGF connective tissue growth factor 0.40008
CD86 CD86 molecule 0.398589
CXCR1 chemokine (C-X-C motif) receptor 1 0.395235
CXCR6 chemokine (C-X-C motif) receptor 6 0.395235
GCSH glycine cleavage system protein H (aminomethyl carrier) 0.378143
SLC7A4 solute carrier family 7, member 4 0.377773
FASLG Fas ligand (TNF superfamily, member 6) 0.37555
PDGFB platelet-derived growth factor beta polypeptide 0.364085
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.362978
VCAM1 vascular cell adhesion molecule 1 0.36187
SLAMF6 SLAM family member 6 0.358551
CRP C-reactive protein, pentraxin-related 0.354499
XCL1 chemokine (C motif) ligand 1 0.351555
HYAL2 hyaluronoglucosaminidase 2 0.346777
PARP15 poly (ADP-ribose) polymerase family, member 15 0.343473
PARP14 poly (ADP-ribose) polymerase family, member 14 0.343106
CD276 CD276 molecule 0.341639
NRN1 neuritin 1 0.339073
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.337608
KNG1 kininogen 1 0.334681
CXCL9 chemokine (C-X-C motif) ligand 9 0.330295
OAT ornithine aminotransferase 0.315003
IL10 interleukin 10 0.30848
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.303781
TIMP1 TIMP metallopeptidase inhibitor 1 0.303059
B2M beta-2-microglobulin 0.299092
THBD thrombomodulin 0.298731
SELE selectin E 0.292975
CXCL16 chemokine (C-X-C motif) ligand 16 0.289744
CPN1 carboxypeptidase N, polypeptide 1 0.28831
CCR2 chemokine (C-C motif) receptor 2 0.28616
MMP9 matrix metallopeptidase 9 0.28616
C4B complement component 4B (Chido blood group) 0.285086
DSC1 desmocollin 1 0.279367
OAZ1 ornithine decarboxylase antizyme 1 0.276514
AGO1 argonaute RISC catalytic component 1 0.275089
NCF2 neutrophil cytosolic factor 2 0.270819
AMT aminomethyltransferase 0.266203
DCTD dCMP deaminase 0.265849
AMY1B amylase, alpha 1B (salivary) 0.26266
AMY1C amylase, alpha 1C (salivary) 0.26266
AMY1A amylase, alpha 1A (salivary) 0.26266
DERL1 derlin 1 0.255241
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.251718
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.245046
CD1A CD1a molecule 0.238403
TSPO translocator protein (18kDa) 0.233878
NT5C1A 5'-nucleotidase, cytosolic IA 0.233183
FOXP3 forkhead box P3 0.227988
CD244 CD244 molecule, natural killer cell receptor 2B4 0.226607
CD14 CD14 molecule 0.226262
LTA lymphotoxin alpha 0.225229
PPT2 palmitoyl-protein thioesterase 2 0.224884
CPB2 carboxypeptidase B2 (plasma) 0.222479
GLRX glutaredoxin (thioltransferase) 0.217012
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.216672
LPO lactoperoxidase 0.214975
PFN2 profilin 2 0.211597
ANPEP alanyl (membrane) aminopeptidase 0.209918
NELFCD negative elongation factor complex member C/D 0.209248
EDN1 endothelin 1 0.204593
NCF4 neutrophil cytosolic factor 4, 40kDa 0.201962
MCM7 minichromosome maintenance complex component 7 0.198709
TGFB2 transforming growth factor, beta 2 0.198386
FIP1L1 factor interacting with PAPOLA and CPSF1 0.19582
HECA headcase homolog (Drosophila) 0.188938
RETNLB resistin like beta 0.18151
HLA-A major histocompatibility complex, class I, A 0.181222
CCL5 chemokine (C-C motif) ligand 5 0.180084
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.179239
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.178682
TAC1 tachykinin, precursor 1 0.177029
IL15 interleukin 15 0.174617
CCR6 chemokine (C-C motif) receptor 6 0.168617
AARS alanyl-tRNA synthetase 0.168148
CAT catalase 0.165874
NCAM1 neural cell adhesion molecule 1 0.165655
PPL periplakin 0.164149
WNT7A wingless-type MMTV integration site family, member 7A 0.163111
RAG1 recombination activating gene 1 0.162306
CCL15 chemokine (C-C motif) ligand 15 0.161139
HMOX1 heme oxygenase 1 0.160574
STAT4 signal transducer and activator of transcription 4 0.158951
MYD88 myeloid differentiation primary response 88 0.158434
HM13 histocompatibility (minor) 13 0.139759
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.138408
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.138046
EDNRB endothelin receptor type B 0.137947
DCD dermcidin 0.137821
CHRM2 cholinergic receptor, muscarinic 2 0.137463
PNPLA6 patatin-like phospholipase domain containing 6 0.136936
CLTC clathrin, heavy chain (Hc) 0.136341
ZFPM1 zinc finger protein, FOG family member 1 0.135452
S100A6 S100 calcium binding protein A6 0.135235
PRKD1 protein kinase D1 0.134249
RPS19 ribosomal protein S19 0.13291
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.132642
GSTP1 glutathione S-transferase pi 1 0.132192
GPANK1 G patch domain and ankyrin repeats 1 0.131917
HMBS hydroxymethylbilane synthase 0.130935
WDFY2 WD repeat and FYVE domain containing 2 0.130868
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.13076
NTF3 neurotrophin 3 0.130347
SRI sorcin 0.129422
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.129192
CCL17 chemokine (C-C motif) ligand 17 0.128287
TES testin LIM domain protein 0.124861
CA2 carbonic anhydrase II 0.124471
MUC2 mucin 2, oligomeric mucus/gel-forming 0.122352
CTRL chymotrypsin-like 0.121125
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.119587
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.118775
GSTTP1 glutathione S-transferase theta pseudogene 1 0.11565
GSTT1 glutathione S-transferase theta 1 0.11565
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.113625
GSR glutathione reductase 0.113442
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.113004
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.112968
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.112405
GATA3 GATA binding protein 3 0.109735
POMC proopiomelanocortin 0.109448
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.108952
GSTM1 glutathione S-transferase mu 1 0.10815
GGT2 gamma-glutamyltransferase 2 0.103116