ethotoin-4545 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the ethotoin-4545 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APAF1 apoptotic peptidase activating factor 1
APP amyloid beta (A4) precursor protein
ARTN artemin
ATF6B activating transcription factor 6 beta
ATG9A autophagy related 9A
ATXN2L ataxin 2-like
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C17ORF53 chromosome 17 open reading frame 53
C4BPA complement component 4 binding protein, alpha
CACFD1 calcium channel flower domain containing 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CD4 CD4 molecule
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CNN1 calponin 1, basic, smooth muscle
COL6A1 collagen, type VI, alpha 1
CORO7 coronin 7
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTSZ cathepsin Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DTNB dystrobrevin, beta
DUOX1 dual oxidase 1
DVL3 dishevelled segment polarity protein 3
EMC1 ER membrane protein complex subunit 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FLJ11710 uncharacterized protein FLJ11710
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAS7 growth arrest-specific 7
GK glycerol kinase
GMPR guanosine monophosphate reductase
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPSM3 G-protein signaling modulator 3
GRM7 glutamate receptor, metabotropic 7
HDAC11 histone deacetylase 11
HIST1H4C histone cluster 1, H4c
HNF1B HNF1 homeobox B
HRASLS2 HRAS-like suppressor 2
IFT27 intraflagellar transport 27
INE1 inactivation escape 1 (non-protein coding)
IRAK4 interleukin-1 receptor-associated kinase 4
IZUMO4 IZUMO family member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MBD2 methyl-CpG binding domain protein 2
MED16 mediator complex subunit 16
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MOBP myelin-associated oligodendrocyte basic protein
MT3 metallothionein 3
NCAM2 neural cell adhesion molecule 2
NNAT neuronatin
NPFF neuropeptide FF-amide peptide precursor
NPM3 nucleophosmin/nucleoplasmin 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PADI1 peptidyl arginine deiminase, type I
PBX2 pre-B-cell leukemia homeobox 2
PCDHB3 protocadherin beta 3
PDE4C phosphodiesterase 4C, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITX1 paired-like homeodomain 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
PRPF18 pre-mRNA processing factor 18
PRRC2B proline-rich coiled-coil 2B
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMS2 RNA binding motif, single stranded interacting protein 2
RHCE Rh blood group, CcEe antigens
RPL10L ribosomal protein L10-like
RUNX1 runt-related transcription factor 1
SARM1 sterile alpha and TIR motif containing 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SLC35E2 solute carrier family 35, member E2
SOS2 son of sevenless homolog 2 (Drosophila)
STXBP5L syntaxin binding protein 5-like
TBC1D2B TBC1 domain family, member 2B
THBD thrombomodulin
TMEM38B transmembrane protein 38B
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
U2AF2 U2 small nuclear RNA auxiliary factor 2
USB1 U6 snRNA biogenesis 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VGLL3 vestigial-like family member 3
ZC3H7B zinc finger CCCH-type containing 7B
ZKSCAN5 zinc finger with KRAB and SCAN domains 5

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANXA10 annexin A10
ASAP1-IT1 ASAP1 intronic transcript 1
BTF3P12 basic transcription factor 3 pseudogene 12
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
C5ORF42 chromosome 5 open reading frame 42
CAPN15 calpain 15
CCNT1 cyclin T1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD70 CD70 molecule
CDH7 cadherin 7, type 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
DCAF16 DDB1 and CUL4 associated factor 16
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM186A family with sequence similarity 186, member A
FBXW12 F-box and WD repeat domain containing 12
FKBP14 FK506 binding protein 14, 22 kDa
FLCN folliculin
FLRT3 fibronectin leucine rich transmembrane protein 3
FZD8 frizzled class receptor 8
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRB glycine receptor, beta
GPR39 G protein-coupled receptor 39
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GUSBP3 glucuronidase, beta pseudogene 3
HELLS helicase, lymphoid-specific
HIST2H2AA3 histone cluster 2, H2aa3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT22 intraflagellar transport 22
IPP intracisternal A particle-promoted polypeptide
KIAA0894 KIAA0894 protein
LIAS lipoic acid synthetase
LOC100286895 cell division cycle 27 homolog pseudogene
LOC440434 aminopeptidase puromycin sensitive pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD11 major facilitator superfamily domain containing 11
MFSD6 major facilitator superfamily domain containing 6
MGC12488
MIS18BP1 MIS18 binding protein 1
MVP major vault protein
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OSMR oncostatin M receptor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RCAN3 RCAN family member 3
RFX7 regulatory factor X, 7
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF146 ring finger protein 146
RSRC1 arginine/serine-rich coiled-coil 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STK19 serine/threonine kinase 19
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYTL2 synaptotagmin-like 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WNT7A wingless-type MMTV integration site family, member 7A
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF230 zinc finger protein 230
ZNF264 zinc finger protein 264
ZNF426 zinc finger protein 426
ZNF587 zinc finger protein 587
ZNF652 zinc finger protein 652
ZNF654 zinc finger protein 654
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721
ZNF768 zinc finger protein 768
ZWILCH zwilch kinetochore protein