ethaverine-3037 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the ethaverine-3037 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AATK apoptosis-associated tyrosine kinase
ABHD6 abhydrolase domain containing 6
ACTA1 actin, alpha 1, skeletal muscle
ADGRB3 adhesion G protein-coupled receptor B3
AKR1C4 aldo-keto reductase family 1, member C4
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMELY amelogenin, Y-linked
AREG amphiregulin
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
AXL AXL receptor tyrosine kinase
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C16ORF45 chromosome 16 open reading frame 45
CARD10 caspase recruitment domain family, member 10
CARTPT CART prepropeptide
CCDC70 coiled-coil domain containing 70
CHN2 chimerin 2
CORO2B coronin, actin binding protein, 2B
CREM cAMP responsive element modulator
CRNN cornulin
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDO D-aspartate oxidase
DNAH17 dynein, axonemal, heavy chain 17
DOCK4 dedicator of cytokinesis 4
DPEP2 dipeptidase 2
DUSP4 dual specificity phosphatase 4
ECE1 endothelin converting enzyme 1
EMILIN2 elastin microfibril interfacer 2
EPHA5 EPH receptor A5
EPN3 epsin 3
FBXL18 F-box and leucine-rich repeat protein 18
FOXO1 forkhead box O1
FRMD8 FERM domain containing 8
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABARAPL1 GABA(A) receptor-associated protein like 1
GPR4 G protein-coupled receptor 4
HLA-DRA major histocompatibility complex, class II, DR alpha
HNMT histamine N-methyltransferase
HR hair growth associated
HRASLS2 HRAS-like suppressor 2
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
ICOSLG inducible T-cell co-stimulator ligand
IDS iduronate 2-sulfatase
IL1R1 interleukin 1 receptor, type I
INSL5 insulin-like 5
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
KRTAP5-9 keratin associated protein 5-9
KYNU kynureninase
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MAOA monoamine oxidase A
MCTP2 multiple C2 domains, transmembrane 2
MXRA8 matrix-remodelling associated 8
MYH11 myosin, heavy chain 11, smooth muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOZ2 myozenin 2
NKX2-1 NK2 homeobox 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRG1 neuregulin 1
NUP188 nucleoporin 188kDa
PAX8 paired box 8
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4B phosphodiesterase 4B, cAMP-specific
PGK2 phosphoglycerate kinase 2
PMEPA1 prostate transmembrane protein, androgen induced 1
PRKG2 protein kinase, cGMP-dependent, type II
PRSS22 protease, serine, 22
PRSS8 protease, serine, 8
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRJ protein tyrosine phosphatase, receptor type, J
RBBP4 retinoblastoma binding protein 4
RECQL5 RecQ protein-like 5
REEP2 receptor accessory protein 2
RUFY3 RUN and FYVE domain containing 3
RYR1 ryanodine receptor 1 (skeletal)
SDC2 syndecan 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIRPB1 signal-regulatory protein beta 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMTN smoothelin
SRPX2 sushi-repeat containing protein, X-linked 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STX2 syntaxin 2
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SV2C synaptic vesicle glycoprotein 2C
TACR1 tachykinin receptor 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TEX40 testis expressed 40
THBS1 thrombospondin 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ADTRP androgen-dependent TFPI-regulating protein
APOL6 apolipoprotein L, 6
ARMCX4 armadillo repeat containing, X-linked 4
ATF3 activating transcription factor 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CCL2 chemokine (C-C motif) ligand 2
CD69 CD69 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST10 carbohydrate sulfotransferase 10
CTH cystathionine gamma-lyase
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DYSF dysferlin
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR2 early growth response 2
ENAH enabled homolog (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
HAMP hepcidin antimicrobial peptide
HCAR3 hydroxycarboxylic acid receptor 3
HHLA3 HERV-H LTR-associating 3
HIST1H2AM histone cluster 1, H2am
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
IDI1 isopentenyl-diphosphate delta isomerase 1
INHBE inhibin, beta E
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KIAA1024 KIAA1024
LRRC20 leucine rich repeat containing 20
LTBP2 latent transforming growth factor beta binding protein 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP9 matrix metallopeptidase 9
NARF nuclear prelamin A recognition factor
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIL3 nuclear factor, interleukin 3 regulated
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PHACTR1 phosphatase and actin regulator 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS13 regulator of G-protein signaling 13
RGS16 regulator of G-protein signaling 16
RHOBTB2 Rho-related BTB domain containing 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMR3A submaxillary gland androgen regulated protein 3A
SPP1 secreted phosphoprotein 1
STBD1 starch binding domain 1
STC2 stanniocalcin 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TEC tec protein tyrosine kinase
THEM6 thioesterase superfamily member 6
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM110 transmembrane protein 110
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNNT1 troponin T type 1 (skeletal, slow)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UPB1 ureidopropionase, beta
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VLDLR very low density lipoprotein receptor
ZBED1 zinc finger, BED-type containing 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZHX2 zinc fingers and homeoboxes 2
ZNF292 zinc finger protein 292
ZNF665 zinc finger protein 665