etamsylate-4576 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the etamsylate-4576 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTN2 actinin, alpha 2
ADTRP androgen-dependent TFPI-regulating protein
AMOT angiomotin
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP10B ATPase, class V, type 10B
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2 B-cell CLL/lymphoma 2
BHMT2 betaine--homocysteine S-methyltransferase 2
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF12 chromosome 10 open reading frame 12
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALD1 caldesmon 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC33 coiled-coil domain containing 33
CD101 CD101 molecule
CDH8 cadherin 8, type 2
CGA glycoprotein hormones, alpha polypeptide
CLCA2 chloride channel accessory 2
CRHR2 corticotropin releasing hormone receptor 2
CRLF1 cytokine receptor-like factor 1
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CTAG2 cancer/testis antigen 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DIAPH2-AS1 DIAPH2 antisense RNA 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ERC2-IT1 ERC2 intronic transcript 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
FAM135A family with sequence similarity 135, member A
FAM174B family with sequence similarity 174, member B
FAM224A family with sequence similarity 224, member A (non-protein coding)
FHIT fragile histidine triad
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GK2 glycerol kinase 2
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GPR183 G protein-coupled receptor 183
HEMK1 HemK methyltransferase family member 1
HIF3A hypoxia inducible factor 3, alpha subunit
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-F major histocompatibility complex, class I, F
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFNA17 interferon, alpha 17
IGHA1 immunoglobulin heavy constant alpha 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1RL1 interleukin 1 receptor-like 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KRT2 keratin 2, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMD1 LIM domains containing 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100129648 uncharacterized LOC100129648
LOC100129973 uncharacterized LOC100129973
LRP4 low density lipoprotein receptor-related protein 4
MMP9 matrix metallopeptidase 9
MORN1 MORN repeat containing 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NOVA2 neuro-oncological ventral antigen 2
NUP160 nucleoporin 160kDa
NUP54 nucleoporin 54kDa
OSBPL10 oxysterol binding protein-like 10
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PCDHA9 protocadherin alpha 9
PCDHB3 protocadherin beta 3
PENK proenkephalin
PEX5L peroxisomal biogenesis factor 5-like
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQBP1 polyglutamine binding protein 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PYHIN1 pyrin and HIN domain family, member 1
RB1 retinoblastoma 1
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SDS serine dehydratase
SERHL2 serine hydrolase-like 2
SLA Src-like-adaptor
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SOCS3 suppressor of cytokine signaling 3
SOGA1 suppressor of glucose, autophagy associated 1
SSX3 synovial sarcoma, X breakpoint 3
SULT4A1 sulfotransferase family 4A, member 1
TBX5 T-box 5
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TMPRSS4 transmembrane protease, serine 4
TRIM25 tripartite motif containing 25
VCL vinculin
ZNF117 zinc finger protein 117
ZNF710 zinc finger protein 710
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
ANP32A-IT1 ANP32A intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF88 chromosome 10 open reading frame 88
C11ORF95 chromosome 11 open reading frame 95
C4ORF29 chromosome 4 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
C9ORF40 chromosome 9 open reading frame 40
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CDADC1 cytidine and dCMP deaminase domain containing 1
CDT1 chromatin licensing and DNA replication factor 1
CEP112 centrosomal protein 112kDa
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
DCAF17 DDB1 and CUL4 associated factor 17
DMTN dematin actin binding protein
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM186A family with sequence similarity 186, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXD1 forkhead box D1
GMEB1 glucocorticoid modulatory element binding protein 1
GREB1L growth regulation by estrogen in breast cancer-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
HS1BP3 HCLS1 binding protein 3
HSPA1L heat shock 70kDa protein 1-like
IL7 interleukin 7
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM4D lysine (K)-specific demethylase 4D
LINC00597 long intergenic non-protein coding RNA 597
LOC730101 uncharacterized LOC730101
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAGEH1 melanoma antigen family H1
MANBA mannosidase, beta A, lysosomal
MOXD1 monooxygenase, DBH-like 1
MTG1 mitochondrial ribosome-associated GTPase 1
MYL5 myosin, light chain 5, regulatory
NDP Norrie disease (pseudoglioma)
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
OVGP1 oviductal glycoprotein 1, 120kDa
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC2 polyhomeotic homolog 2 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPAN peter pan homolog (Drosophila)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB5B RAB5B, member RAS oncogene family
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUSC2 RUN and SH3 domain containing 2
SLC46A3 solute carrier family 46, member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNHG20 small nucleolar RNA host gene 20
SNPH syntaphilin
STON1 stonin 1
SUGCT succinyl-CoA:glutarate-CoA transferase
SYT17 synaptotagmin XVII
TEP1 telomerase-associated protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
THOP1 thimet oligopeptidase 1
TMEM51 transmembrane protein 51
TRABD TraB domain containing
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TUBA3C tubulin, alpha 3c
UGT8 UDP glycosyltransferase 8
UNKL unkempt family zinc finger-like
WDR18 WD repeat domain 18
WDR4 WD repeat domain 4
ZNF197 zinc finger protein 197
ZNF212 zinc finger protein 212
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF408 zinc finger protein 408
ZNF551 zinc finger protein 551
ZNF668 zinc finger protein 668
ZNF702P zinc finger protein 702, pseudogene