esophageal carcinoma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A esophageal cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (Human Disease Ontology, DOID_1107)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0011459
Similar Terms
Downloads & Tools

Genes

104 genes associated with the esophageal carcinoma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.67356
PLCE1 phospholipase C, epsilon 1 2.61084
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.38717
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.2397
CHEK2 checkpoint kinase 2 2.0492
RUNX1 runt-related transcription factor 1 2.03298
ACAD10 acyl-CoA dehydrogenase family, member 10 2.00018
HEATR3 HEAT repeat containing 3 1.97023
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 1.95283
PDE4D phosphodiesterase 4D, cAMP-specific 1.9268
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 1.74655
XBP1 X-box binding protein 1 1.72215
CHRM2 cholinergic receptor, muscarinic 2 1.68114
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.65276
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 1.6456
FCRL6 Fc receptor-like 6 1.64284
TRAFD1 TRAF-type zinc finger domain containing 1 1.52492
BRAP BRCA1 associated protein 1.52422
CCDC63 coiled-coil domain containing 63 1.51992
SMG6 SMG6 nonsense mediated mRNA decay factor 1.48419
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.48419
SLC22A17 solute carrier family 22, member 17 1.47491
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.39533
PES1 pescadillo ribosomal biogenesis factor 1 1.36393
SYK spleen tyrosine kinase 1.36147
NANP N-acetylneuraminic acid phosphatase 1.33984
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.28507
CSNK1A1 casein kinase 1, alpha 1 1.28282
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 1.27321
HSP90AA6P heat shock protein 90kDa alpha (cytosolic), class A member 6, pseudogene 1.25904
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) 1.2439
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.18704
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B 1.15352
OCA2 oculocutaneous albinism II 1.15278
TMC1 transmembrane channel-like 1 1.15033
MTAP methylthioadenosine phosphorylase 1.1457
PEBP4 phosphatidylethanolamine-binding protein 4 1.13746
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.13214
FKBP1A FK506 binding protein 1A, 12kDa 1.12812
MCC mutated in colorectal cancers 1.12715
KANK1 KN motif and ankyrin repeat domains 1 1.12265
CLN3 ceroid-lipofuscinosis, neuronal 3 1.11993
WWOX WW domain containing oxidoreductase 1.11685
SREBF2 sterol regulatory element binding transcription factor 2 1.11638
DGKH diacylglycerol kinase, eta 1.11472
TFDP1 transcription factor Dp-1 1.11371
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.10674
MUC1 mucin 1, cell surface associated 1.09906
TSPAN11 tetraspanin 11 1.08492
ZFAND5 zinc finger, AN1-type domain 5 1.08459
CCDC101 coiled-coil domain containing 101 1.08287
TEX41 testis expressed 41 (non-protein coding) 1.08091
FAM167A family with sequence similarity 167, member A 1.07941
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 1.07682
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.06722
IL18R1 interleukin 18 receptor 1 1.06202
JAZF1 JAZF zinc finger 1 1.06127
AMPH amphiphysin 1.06025
TBL2 transducin (beta)-like 2 1.0586
TRPC4 transient receptor potential cation channel, subfamily C, member 4 1.05792
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.05081
AGBL4 ATP/GTP binding protein-like 4 1.04948
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 1.03374
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.03217
PTPRM protein tyrosine phosphatase, receptor type, M 1.03217
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 1.02549
ATF1 activating transcription factor 1 1.02289
POSTN periostin, osteoblast specific factor 1.0154
USP18 ubiquitin specific peptidase 18 1.0118
DOCK9 dedicator of cytokinesis 9 1.00952
JAZF1-AS1 JAZF1 antisense RNA 1 1.00769
AXDND1 axonemal dynein light chain domain containing 1 0.992871
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.98964
ATXN2L ataxin 2-like 0.985675
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.973389
SPNS1 spinster homolog 1 (Drosophila) 0.973389
LOC646762 uncharacterized LOC646762 0.964368
CADM2 cell adhesion molecule 2 0.964112
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.96335
THOC5 THO complex 5 0.962749
CLYBL citrate lyase beta like 0.95642
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.953171
IL1RAP interleukin 1 receptor accessory protein 0.951856
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.94116
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.917536
HCG18 HLA complex group 18 (non-protein coding) 0.91046
DOCK2 dedicator of cytokinesis 2 0.904931
ABHD6 abhydrolase domain containing 6 0.903414
KIAA0368 KIAA0368 0.903226
OSMR oncostatin M receptor 0.883951
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.879831
BPTF bromodomain PHD finger transcription factor 0.852971
ADH6 alcohol dehydrogenase 6 (class V) 0.823019
CCDC117 coiled-coil domain containing 117 0.819829
ESRRG estrogen-related receptor gamma 0.798387
TSC22D2 TSC22 domain family, member 2 0.791675
BDNF-AS BDNF antisense RNA 0.791087
FADS1 fatty acid desaturase 1 0.784165
PCDH7 protocadherin 7 0.779456
MTMR3 myotubularin related protein 3 0.756753
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.748581
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.748581
TMCC1 transmembrane and coiled-coil domain family 1 0.57412
ELP2 elongator acetyltransferase complex subunit 2 0.481126