escrt-0 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals. (Gene Ontology, GO_0033565)
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69 proteins co-occuring with the escrt-0 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.89385
USP8 ubiquitin specific peptidase 8 1.83067
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 1.80039
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 1.77927
TOM1 target of myb1 (chicken) 1.55821
TOM1L1 target of myb1 (chicken)-like 1 1.54235
TOM1L2 target of myb1-like 2 (chicken) 1.46043
TSG101 tumor susceptibility 101 1.3532
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.21221
DTX3L deltex 3 like, E3 ubiquitin ligase 1.18748
CHMP3 charged multivesicular body protein 3 1.18389
RNF11 ring finger protein 11 1.13676
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.950665
TOLLIP toll interacting protein 0.822206
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 0.775471
CHMP6 charged multivesicular body protein 6 0.774558
CXCR4 chemokine (C-X-C motif) receptor 4 0.774101
ZFYVE9 zinc finger, FYVE domain containing 9 0.760887
SCAMP3 secretory carrier membrane protein 3 0.755437
UBD ubiquitin D 0.724365
LMTK2 lemur tyrosine kinase 2 0.717236
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.701744
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.680719
UBE4B ubiquitination factor E4B 0.679849
CHMP4B charged multivesicular body protein 4B 0.654311
EGFR epidermal growth factor receptor 0.616709
CHMP4A charged multivesicular body protein 4A 0.614165
SNF8 SNF8, ESCRT-II complex subunit 0.595593
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.587618
STAB1 stabilin 1 0.559285
MYLIP myosin regulatory light chain interacting protein 0.536594
PARK2 parkin RBR E3 ubiquitin protein ligase 0.535361
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.521432
CHMP5 charged multivesicular body protein 5 0.521023
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.503912
SPRY2 sprouty homolog 2 (Drosophila) 0.494585
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 0.49418
ITCH itchy E3 ubiquitin protein ligase 0.474822
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.463598
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.457208
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 0.453621
ARRB1 arrestin, beta 1 0.44052
CCR4 chemokine (C-C motif) receptor 4 0.43617
CHMP2B charged multivesicular body protein 2B 0.415728
IL4R interleukin 4 receptor 0.410649
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.400916
RAD23B RAD23 homolog B (S. cerevisiae) 0.383895
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.364331
KDR kinase insert domain receptor 0.363567
OPTN optineurin 0.357467
GIPC1 GIPC PDZ domain containing family, member 1 0.357086
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.344178
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.331342
CHMP2A charged multivesicular body protein 2A 0.31596
CALCOCO2 calcium binding and coiled-coil domain 2 0.313344
STAB2 stabilin 2 0.309986
SNX1 sorting nexin 1 0.308867
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.291417
EEA1 early endosome antigen 1 0.2708
CD63 CD63 molecule 0.266408
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.258745
SORT1 sortilin 1 0.246407
CXCL12 chemokine (C-X-C motif) ligand 12 0.246046
CXCR1 chemokine (C-X-C motif) receptor 1 0.24424
GRB2 growth factor receptor-bound protein 2 0.232386
BST2 bone marrow stromal cell antigen 2 0.195025
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.175188
PARD6A par-6 family cell polarity regulator alpha 0.16477
CXCR2 chemokine (C-X-C motif) receptor 2 0.164542