esc/e(z) complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. (Gene Ontology, GO_0035098)
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10 proteins localized to the esc/e(z) complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EED embryonic ectoderm development 0.663342
RBBP4 retinoblastoma binding protein 4 0.663342
RBBP7 retinoblastoma binding protein 7 0.663342
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.663342
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.663342
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.663342
HDAC2 histone deacetylase 2 0.663342
AEBP2 AE binding protein 2 0.663342
MTF2 metal response element binding transcription factor 2 0.03318
PHF19 PHD finger protein 19 0.03318