erk1 and erk2 cascade Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. (Gene Ontology, GO_0070371)
External Link http://amigo.geneontology.org/amigo/term/GO:0070371
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Genes

18 genes participating in the erk1 and erk2 cascade biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOA1 apolipoprotein A-I
AVP arginine vasopressin
CCL11 chemokine (C-C motif) ligand 11
CTSH cathepsin H
EGF epidermal growth factor
FGF10 fibroblast growth factor 10
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IQGAP3 IQ motif containing GTPase activating protein 3
ITGAV integrin, alpha V
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MED1 mediator complex subunit 1
MT3 metallothionein 3
OXTR oxytocin receptor
PTGER4 prostaglandin E receptor 4 (subtype EP4)
SOX9 SRY (sex determining region Y)-box 9
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11