epilepsy syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions. (Human Disease Ontology, DOID_1826)
Similar Terms
Downloads & Tools

Genes

599 genes co-occuring with the disease epilepsy syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SCN1A sodium channel, voltage gated, type I alpha subunit 3.41439
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 2.68322
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.55283
SCN1B sodium channel, voltage gated, type I beta subunit 2.45173
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.45173
SCN3A sodium channel, voltage gated, type III alpha subunit 2.4372
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.39899
CSTB cystatin B (stefin B) 2.36595
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 2.32155
LGI1 leucine-rich, glioma inactivated 1 2.27112
EFHC1 EF-hand domain (C-terminal) containing 1 2.22339
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.1608
PRRT2 proline-rich transmembrane protein 2 1.94501
SCN2A sodium channel, voltage gated, type II alpha subunit 1.91921
STXBP1 syntaxin binding protein 1 1.86735
PCDH19 protocadherin 19 1.85501
CLCN2 chloride channel, voltage-sensitive 2 1.77947
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.72867
DEPDC5 DEP domain containing 5 1.57022
LGI2 leucine-rich repeat LGI family, member 2 1.50008
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.48735
LGI4 leucine-rich repeat LGI family, member 4 1.4856
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.46539
SCN2B sodium channel, voltage gated, type II beta subunit 1.3869
PFKL phosphofructokinase, liver 1.3773
PCDH10 protocadherin 10 1.36074
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.34897
ELP4 elongator acetyltransferase complex subunit 4 1.34199
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.3337
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 1.33109
CAPN1 calpain 1, (mu/I) large subunit 1.32367
JRK Jrk homolog (mouse) 1.32105
EPM2AIP1 EPM2A (laforin) interacting protein 1 1.27301
PARK2 parkin RBR E3 ubiquitin protein ligase 1.26691
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 1.22345
POMC proopiomelanocortin 1.21478
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 1.19704
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 1.18539
PRICKLE1 prickle homolog 1 (Drosophila) 1.17206
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.1588
STRADA STE20-related kinase adaptor alpha 1.14475
SV2A synaptic vesicle glycoprotein 2A 1.13501
DCX doublecortin 1.11351
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 1.11225
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 1.11183
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.10384
ADAM22 ADAM metallopeptidase domain 22 1.10048
BRD2 bromodomain containing 2 1.09461
PAQR8 progestin and adipoQ receptor family member VIII 1.0795
PVALB parvalbumin 1.07068
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 1.0669
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.05723
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.05681
PPP1R3C protein phosphatase 1, regulatory subunit 3C 1.05597
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 1.04377
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.02735
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 1.02144
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.02018
ARX aristaless related homeobox 1.01934
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.0168
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.01343
SRPX2 sushi-repeat containing protein, X-linked 2 1.0071
LGI3 leucine-rich repeat LGI family, member 3 1.00499
EMX2 empty spiracles homeobox 2 0.998236
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.996127
TBC1D24 TBC1 domain family, member 24 0.993174
SYN3 synapsin III 0.990222
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.980952
SYN2 synapsin II 0.97212
ADGRV1 adhesion G protein-coupled receptor V1 0.961634
CNTNAP2 contactin associated protein-like 2 0.960797
PDCL phosducin-like 0.958287
POLG polymerase (DNA directed), gamma 0.952856
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.952021
DMGDH dimethylglycine dehydrogenase 0.942858
CSNK1G1 casein kinase 1, gamma 1 0.94078
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.936629
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.934141
GARS glycyl-tRNA synthetase 0.929587
RELN reelin 0.929587
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.926692
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 0.923387
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.919261
PPP1R3D protein phosphatase 1, regulatory subunit 3D 0.916787
TMEM2 transmembrane protein 2 0.914315
C9ORF41 chromosome 9 open reading frame 41 0.895
C9ORF40 chromosome 9 open reading frame 40 0.895
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.893769
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 0.890898
ADGRG1 adhesion G protein-coupled receptor G1 0.889258
EMX1 empty spiracles homeobox 1 0.886389
CLN5 ceroid-lipofuscinosis, neuronal 5 0.881472
MFSD8 major facilitator superfamily domain containing 8 0.880653
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.875738
TBC1D22A TBC1 domain family, member 22A 0.875329
PCDHA8 protocadherin alpha 8 0.869187
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.858543
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 0.849126
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 0.834788
PNPO pyridoxamine 5'-phosphate oxidase 0.824538
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.823308
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.821257
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.817565
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 0.81018
ROGDI rogdi homolog (Drosophila) 0.803616
LRRC1 leucine rich repeat containing 1 0.802795
F2 coagulation factor II (thrombin) 0.793361
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.791721
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 0.790081
GPHN gephyrin 0.788033
SET SET nuclear proto-oncogene 0.777386
CDKL5 cyclin-dependent kinase-like 5 0.77207
PPME1 protein phosphatase methylesterase 1 0.767985
PRDM8 PR domain containing 8 0.757378
TMEM14A transmembrane protein 14A 0.754527
ADAM23 ADAM metallopeptidase domain 23 0.752492
AKAP6 A kinase (PRKA) anchor protein 6 0.741517
GBP6 guanylate binding protein family, member 6 0.738271
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.734217
TAAR5 trace amine associated receptor 5 0.728143
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.727738
SCN4B sodium channel, voltage gated, type IV beta subunit 0.727333
VRK2 vaccinia related kinase 2 0.726929
NNAT neuronatin 0.723694
TRAPPC10 trafficking protein particle complex 10 0.722077
FLNA filamin A, alpha 0.709572
PNKD paroxysmal nonkinesigenic dyskinesia 0.707157
NFU1 NFU1 iron-sulfur cluster scaffold 0.705547
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 0.70434
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.702732
MEOX2 mesenchyme homeobox 2 0.699517
TSC2 tuberous sclerosis 2 0.683093
PTPRD protein tyrosine phosphatase, receptor type, D 0.679499
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.677105
FBXO9 F-box protein 9 0.674713
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.671527
POLI polymerase (DNA directed) iota 0.661594
GOSR2 golgi SNAP receptor complex member 2 0.656046
C14ORF1 chromosome 14 open reading frame 1 0.654858
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.649323
OSTF1 osteoclast stimulating factor 1 0.648533
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.643797
TRAM2 translocation associated membrane protein 2 0.643009
GRIK1 glutamate receptor, ionotropic, kainate 1 0.642615
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.639857
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.637102
SCARB2 scavenger receptor class B, member 2 0.635921
MTMR7 myotubularin related protein 7 0.632384
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 0.62885
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.626888
CA4 carbonic anhydrase IV 0.625711
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 0.625711
CTSS cathepsin S 0.623359
ADAM28 ADAM metallopeptidase domain 28 0.621792
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.620617
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.612011
ATP13A4 ATPase type 13A4 0.610057
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.607714
TCTE1 t-complex-associated-testis-expressed 1 0.604981
CPA6 carboxypeptidase A6 0.60069
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.59952
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.595233
GFAP glial fibrillary acidic protein 0.583552
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.582773
GLRA3 glycine receptor, alpha 3 0.581606
CLN3 ceroid-lipofuscinosis, neuronal 3 0.578883
ABAT 4-aminobutyrate aminotransferase 0.574217
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 0.574217
FOS FBJ murine osteosarcoma viral oncogene homolog 0.573439
PYGB phosphorylase, glycogen; brain 0.572273
GRIK5 glutamate receptor, ionotropic, kainate 5 0.571884
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.570718
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.570329
PYGL phosphorylase, glycogen, liver 0.568775
BDNF brain-derived neurotrophic factor 0.561392
PTPRB protein tyrosine phosphatase, receptor type, B 0.55712
MTMR9 myotubularin related protein 9 0.555568
CHD2 chromodomain helicase DNA binding protein 2 0.55518
EPHA10 EPH receptor A10 0.545868
PYGM phosphorylase, glycogen, muscle 0.541992
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 0.541605
HIST1H1E histone cluster 1, H1e 0.540829
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.535022
EFHC2 EF-hand domain (C-terminal) containing 2 0.530768
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.524588
STX7 syntaxin 7 0.51919
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.514186
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.511496
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.508424
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.504973
TPT1 tumor protein, translationally-controlled 1 0.503058
ADAM11 ADAM metallopeptidase domain 11 0.498467
TSPYL4 TSPY-like 4 0.497321
TRH thyrotropin-releasing hormone 0.496557
NFASC neurofascin 0.495411
HCG4P11 HLA complex group 4 pseudogene 11 0.487407
HLA-F major histocompatibility complex, class I, F 0.487407
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.486646
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.482084
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.481325
CLASP2 cytoplasmic linker associated protein 2 0.480945
VCL vinculin 0.479047
DCP1A decapping mRNA 1A 0.476014
SGCZ sarcoglycan, zeta 0.475255
ASPH aspartate beta-hydroxylase 0.472604
CAMP cathelicidin antimicrobial peptide 0.471846
FRMD6 FERM domain containing 6 0.463905
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.462016
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.461639
ANKRD54 ankyrin repeat domain 54 0.460883
TRAK1 trafficking protein, kinesin binding 1 0.458241
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.458241
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.457864
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 0.457487
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.455224
PGLYRP3 peptidoglycan recognition protein 3 0.452208
CTSB cathepsin B 0.449194
PDCD6IP programmed cell death 6 interacting protein 0.445429
BSN bassoon presynaptic cytomatrix protein 0.445052
PCDHGA10 protocadherin gamma subfamily A, 10 0.440538
CDH9 cadherin 9, type 2 (T1-cadherin) 0.438658
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.437906
RORB RAR-related orphan receptor B 0.431519
C10ORF2 chromosome 10 open reading frame 2 0.427015
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 0.424389
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.420641
KPNB1 karyopherin (importin) beta 1 0.414276
OPRM1 opioid receptor, mu 1 0.405678
STX8 syntaxin 8 0.404557
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.39598
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 0.395608
MEA1 male-enhanced antigen 1 0.395608
PCDH7 protocadherin 7 0.393374
SYT11 synaptotagmin XI 0.390025
CLIP1 CAP-GLY domain containing linker protein 1 0.388538
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.384451
CELF4 CUGBP, Elav-like family member 4 0.383337
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.38111
SUOX sulfite oxidase 0.378885
GRM5 glutamate receptor, metabotropic 5 0.378143
GRM4 glutamate receptor, metabotropic 4 0.370737
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.36704
NME1-NME2 NME1-NME2 readthrough 0.365932
UBIAD1 UbiA prenyltransferase domain containing 1 0.365562
TPH1 tryptophan hydroxylase 1 0.362609
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.360764
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.359657
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.359289
CHURC1 churchill domain containing 1 0.358551
PDLIM4 PDZ and LIM domain 4 0.355235
SCN3B sodium channel, voltage gated, type III beta subunit 0.354499
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.354131
EFNA4 ephrin-A4 0.346042
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.340906
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.340906
WNT8B wingless-type MMTV integration site family, member 8B 0.337975
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.336876
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.333218
ACP1 acid phosphatase 1, soluble 0.332852
EMP3 epithelial membrane protein 3 0.331025
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.331025
TPP1 tripeptidyl peptidase I 0.328105
GRM1 glutamate receptor, metabotropic 1 0.327375
SHBG sex hormone-binding globulin 0.325552
COL6A2 collagen, type VI, alpha 2 0.32373
CTSF cathepsin F 0.323365
FLII flightless I homolog (Drosophila) 0.322273
NFYB nuclear transcription factor Y, beta 0.321545
CCNI cyclin I 0.318272
NRXN1 neurexin 1 0.318272
WTAP Wilms tumor 1 associated protein 0.316092
PFKM phosphofructokinase, muscle 0.315003
GKN1 gastrokine 1 0.314278
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.313189
GAL galanin/GMAP prepropeptide 0.312827
PNKP polynucleotide kinase 3'-phosphatase 0.312464
TSC1 tuberous sclerosis 1 0.311014
DIAPH3 diaphanous-related formin 3 0.310652
GLUL glutamate-ammonia ligase 0.300533
TUBA1A tubulin, alpha 1a 0.296931
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.296211
ZNF224 zinc finger protein 224 0.294772
MGAM maltase-glucoamylase 0.293334
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.292975
GAA glucosidase, alpha; acid 0.29118
TK2 thymidine kinase 2, mitochondrial 0.289386
CALB1 calbindin 1, 28kDa 0.286877
GRIK2 glutamate receptor, ionotropic, kainate 2 0.28616
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 0.28616
ELOVL5 ELOVL fatty acid elongase 5 0.285444
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.283655
TP63 tumor protein p63 0.28151
DNER delta/notch-like EGF repeat containing 0.278297
PARD3 par-3 family cell polarity regulator 0.276514
GYG1 glycogenin 1 0.275445
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.275445
CST4 cystatin S 0.274021
SIL1 SIL1 nucleotide exchange factor 0.273664
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.273308
TLE4 transducin-like enhancer of split 4 0.272241
GLRA2 glycine receptor, alpha 2 0.263368
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 0.263368
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.263014
FKTN fukutin 0.260184
CENPB centromere protein B, 80kDa 0.257711
SLC7A4 solute carrier family 7, member 4 0.257711
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 0.24996
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.248554
GLRA1 glycine receptor, alpha 1 0.248554
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 0.246799
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.243645
FBXO44 F-box protein 44 0.243295
AVIL advillin 0.243295
DTNA dystrobrevin, alpha 0.23945
NOVA2 neuro-oncological ventral antigen 2 0.238054
SST somatostatin 0.23492
HRAS Harvey rat sarcoma viral oncogene homolog 0.234573
DNAH8 dynein, axonemal, heavy chain 8 0.23353
DLX1 distal-less homeobox 1 0.232142
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.228679
F10 coagulation factor X 0.228333
SARS seryl-tRNA synthetase 0.224884
SYN1 synapsin I 0.22454
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.224196
EMP1 epithelial membrane protein 1 0.220424
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.217352
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.217012
MRO maestro 0.216332
NPS neuropeptide S 0.210589
CPLX2 complexin 2 0.209248
GRM8 glutamate receptor, metabotropic 8 0.207578
GRM7 glutamate receptor, metabotropic 7 0.206248
SRPR signal recognition particle receptor (docking protein) 0.205585
ST5 suppression of tumorigenicity 5 0.203604
FOXG1 forkhead box G1 0.201635
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.200331
IGBP1 immunoglobulin (CD79A) binding protein 1 0.19742
GRM2 glutamate receptor, metabotropic 2 0.194865
TOR1A torsin family 1, member A (torsin A) 0.194865
TMPRSS3 transmembrane protease, serine 3 0.1936
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.193285
NPY neuropeptide Y 0.191719
STIP1 stress-induced phosphoprotein 1 0.191097
CNTN2 contactin 2 (axonal) 0.188632
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.18651
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.18621
FBXO17 F-box protein 17 0.185313
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.185313
ADK adenosine kinase 0.18472
CBS cystathionine-beta-synthase 0.183835
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.182957
NLGN1 neuroligin 1 0.182086
MMP12 matrix metallopeptidase 12 0.180937
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.178403
PPT1 palmitoyl-protein thioesterase 1 0.171535
DIO1 deiodinase, iodothyronine, type I 0.171286
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.170789
NID2 nidogen 2 (osteonidogen) 0.167452
RHCE Rh blood group, CcEe antigens 0.162707
MAP3K12 mitogen-activated protein kinase kinase kinase 12 0.161716
PTBP2 polypyrimidine tract binding protein 2 0.160387
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.158266
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.128235
GLDC glycine dehydrogenase (decarboxylating) 0.126869
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.126648
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.125335
SPTBN2 spectrin, beta, non-erythrocytic 2 0.124301
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.124247
C1QB complement component 1, q subcomponent, B chain 0.124109
ERBB4 erb-b2 receptor tyrosine kinase 4 0.123921
TRIM32 tripartite motif containing 32 0.123079
CUX1 cut-like homeobox 1 0.123046
TREM2 triggering receptor expressed on myeloid cells 2 0.122316
DVL2 dishevelled segment polarity protein 2 0.122198
DUSP3 dual specificity phosphatase 3 0.122108
CYLD cylindromatosis (turban tumor syndrome) 0.121898
MT2A metallothionein 2A 0.121863
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.120867
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.118709
STX1A syntaxin 1A (brain) 0.117766
SRRM1 serine/arginine repetitive matrix 1 0.117123
BPGM 2,3-bisphosphoglycerate mutase 0.115585
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.115555
PGAM2 phosphoglycerate mutase 2 (muscle) 0.115371
SACS sacsin molecular chaperone 0.114967
ADAR adenosine deaminase, RNA-specific 0.113363
HIF3A hypoxia inducible factor 3, alpha subunit 0.113297
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.112959
DPYSL2 dihydropyrimidinase-like 2 0.111187
PSAP prosaposin 0.109954
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.108892
RYR3 ryanodine receptor 3 0.108482
FOXP2 forkhead box P2 0.108425
DPT dermatopontin 0.108197
EPHA5 EPH receptor A5 0.107672
MNX1 motor neuron and pancreas homeobox 1 0.107241
MECR mitochondrial trans-2-enoyl-CoA reductase 0.106685
PLAUR plasminogen activator, urokinase receptor 0.106604
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.106524
EPHB2 EPH receptor B2 0.106202
HBP1 HMG-box transcription factor 1 0.106162
MECP2 methyl CpG binding protein 2 0.105838
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.105704
PERP PERP, TP53 apoptosis effector 0.105497
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.105467
MEF2C myocyte enhancer factor 2C 0.105085
NBPF8 neuroblastoma breakpoint family, member 8 0.10493
CA2 carbonic anhydrase II 0.104899
PRDX6 peroxiredoxin 6 0.104889
GBA glucosidase, beta, acid 0.104658
NCR3 natural cytotoxicity triggering receptor 3 0.103885
INHA inhibin, alpha 0.103758
BTD biotinidase 0.103522
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.103349
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.103338
WWOX WW domain containing oxidoreductase 0.103197
CKAP5 cytoskeleton associated protein 5 0.103164
TBP TATA box binding protein 0.103088
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.102708
PRTN3 proteinase 3 0.102665
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.102303
PGAM1 phosphoglycerate mutase 1 (brain) 0.101391
FSCN3 fascin actin-bundling protein 3, testicular 0.101223
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.101178
HFE hemochromatosis 0.100791
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.100665
TYROBP TYRO protein tyrosine kinase binding protein 0.100608
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.100586
RERE arginine-glutamic acid dipeptide (RE) repeats 0.100063
IARS isoleucyl-tRNA synthetase 0.09962
FSCN2 fascin actin-bundling protein 2, retinal 0.09962
IVD isovaleryl-CoA dehydrogenase 0.099225
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.098783
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.098783
APOD apolipoprotein D 0.09839
CTSE cathepsin E 0.098354
EFS embryonal Fyn-associated substrate 0.098175
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.098092
HSPA4 heat shock 70kDa protein 4 0.097831
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.097352
MTSS1 metastasis suppressor 1 0.097266
RHD Rh blood group, D antigen 0.096756
NRG1 neuregulin 1 0.096295
CDH13 cadherin 13 0.095701
TXNL1 thioredoxin-like 1 0.095317
CAV3 caveolin 3 0.095069
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.094821
MYRF myelin regulatory factor 0.094618
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.094213
GALC galactosylceramidase 0.094087
FSCN1 fascin actin-bundling protein 1 0.093377
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.092591
EXT1 exostosin glycosyltransferase 1 0.090739
ACHE acetylcholinesterase (Yt blood group) 0.090673
WNT10A wingless-type MMTV integration site family, member 10A 0.090406
PCDH11Y protocadherin 11 Y-linked 0.09038
MAOB monoamine oxidase B 0.090073
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.089165
ANKH ANKH inorganic pyrophosphate transport regulator 0.089029
SYT1 synaptotagmin I 0.087246
PCDH11X protocadherin 11 X-linked 0.087205
FGD1 FYVE, RhoGEF and PH domain containing 1 0.086696
LARS leucyl-tRNA synthetase 0.086669
C1QBP complement component 1, q subcomponent binding protein 0.083546
PLP1 proteolipid protein 1 0.082905
HAS1 hyaluronan synthase 1 0.082662
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.081817
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.081774
LY6E lymphocyte antigen 6 complex, locus E 0.081529
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.081456
ELL elongation factor RNA polymerase II 0.081166
SIX2 SIX homeobox 2 0.080616
WARS tryptophanyl-tRNA synthetase 0.079421
ASRGL1 asparaginase like 1 0.079289
ADSL adenylosuccinate lyase 0.079055
EFNA5 ephrin-A5 0.078865
PTBP1 polypyrimidine tract binding protein 1 0.078719
FAT1 FAT atypical cadherin 1 0.07804
RAD52 RAD52 homolog (S. cerevisiae) 0.07804
BCO1 beta-carotene oxygenase 1 0.078011
CTSH cathepsin H 0.077774
MNT MAX network transcriptional repressor 0.077568
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.077509
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.077494
MAPK14 mitogen-activated protein kinase 14 0.076097
PFN2 profilin 2 0.075815
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.075695
ATN1 atrophin 1 0.075547
PROS1 protein S (alpha) 0.075353
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.075248
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.074016
CRYGD crystallin, gamma D 0.073383
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.072597
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.072416
FANCL Fanconi anemia, complementation group L 0.072069
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.071993
DAND5 DAN domain family member 5, BMP antagonist 0.071719
F5 coagulation factor V (proaccelerin, labile factor) 0.070989
HBG2 hemoglobin, gamma G 0.070671
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.070595
AIRE autoimmune regulator 0.069679
AK6 adenylate kinase 6 0.069587
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.068548
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.066263
AATF apoptosis antagonizing transcription factor 0.065726
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 0.06568
GALR1 galanin receptor 1 0.065649
GALR2 galanin receptor 2 0.065527
F3 coagulation factor III (thromboplastin, tissue factor) 0.065511
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.065342
LMNA lamin A/C 0.065142
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.065065
COPS2 COP9 signalosome subunit 2 0.065049
GRIK4 glutamate receptor, ionotropic, kainate 4 0.064711
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.064664
TWIST2 twist family bHLH transcription factor 2 0.064526
PDYN prodynorphin 0.064372
CRH corticotropin releasing hormone 0.064265
ADA adenosine deaminase 0.064157
GJD2 gap junction protein, delta 2, 36kDa 0.064096
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.063758
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.063742
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.06328
MCM3 minichromosome maintenance complex component 3 0.063203
LSR lipolysis stimulated lipoprotein receptor 0.062972
GHRL ghrelin/obestatin prepropeptide 0.062895
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.062864
WASF3 WAS protein family, member 3 0.062772
CGA glycoprotein hormones, alpha polypeptide 0.062726
CFP complement factor properdin 0.062572
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.061865
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.061834
CA14 carbonic anhydrase XIV 0.061603
TNNT1 troponin T type 1 (skeletal, slow) 0.061541
CTXN2 cortexin 2 0.061234
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.061018
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.061003
SEPT2 septin 2 0.061003
CTSL cathepsin L 0.060727
GAN gigaxonin 0.060404
UBE2H ubiquitin-conjugating enzyme E2H 0.060127
CREB1 cAMP responsive element binding protein 1 0.060081
PLG plasminogen 0.059881
TNC tenascin C 0.059743
KLK8 kallikrein-related peptidase 8 0.059682
SLC45A2 solute carrier family 45, member 2 0.059651
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.059574
HLA-C major histocompatibility complex, class I, C 0.059574
AQP4 aquaporin 4 0.059482
CPSF3L cleavage and polyadenylation specific factor 3-like 0.05916
CHGA chromogranin A 0.059083
LXN latexin 0.059068
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.059007
BOC BOC cell adhesion associated, oncogene regulated 0.058961
SGK1 serum/glucocorticoid regulated kinase 1 0.058823
NIPBL Nipped-B homolog (Drosophila) 0.058807
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.058685
MX1 MX dynamin-like GTPase 1 0.058593
FMR1 fragile X mental retardation 1 0.058332
RGMA repulsive guidance molecule family member a 0.058332
APTX aprataxin 0.058271
CTSK cathepsin K 0.058087
MRI1 methylthioribose-1-phosphate isomerase 1 0.058056
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.057857
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.057811
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.057719
MBP myelin basic protein 0.057383
NEFL neurofilament, light polypeptide 0.057306
PIDD1 p53-induced death domain protein 1 0.057245
TH tyrosine hydroxylase 0.057215
SETD2 SET domain containing 2 0.057169
WDR20 WD repeat domain 20 0.056772
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.056711
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.056634
S100B S100 calcium binding protein B 0.056573
DCLK3 doublecortin-like kinase 3 0.056314
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.056283
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.056131
FUS FUS RNA binding protein 0.056116
ADAM12 ADAM metallopeptidase domain 12 0.055933
CTSD cathepsin D 0.055841
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.05575
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.055735
SETD1A SET domain containing 1A 0.055689
NGF nerve growth factor (beta polypeptide) 0.055674
AMPH amphiphysin 0.055582
HSF1 heat shock transcription factor 1 0.055461
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.0554
CAV2 caveolin 2 0.055172
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.055141
NMT1 N-myristoyltransferase 1 0.054868
CD79A CD79a molecule, immunoglobulin-associated alpha 0.054822
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.054655
CP ceruloplasmin (ferroxidase) 0.054534
PRRC2A proline-rich coiled-coil 2A 0.054443
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.054382
F13A1 coagulation factor XIII, A1 polypeptide 0.054094
PLAU plasminogen activator, urokinase 0.053867
HSPA8 heat shock 70kDa protein 8 0.053806