enzyme inhibitor activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Stops, prevents or reduces the activity of an enzyme. (Gene Ontology, GO_0004857)
External Link http://amigo.geneontology.org/amigo/term/GO:0004857
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Genes

329 genes performing the enzyme inhibitor activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
AMBP alpha-1-microglobulin/bikunin precursor
ANGPTL3 angiopoietin-like 3
ANGPTL4 angiopoietin-like 4
ANOS1 anosmin 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA1 annexin A1
ANXA2 annexin A2
ANXA3 annexin A3
ANXA4 annexin A4
ANXA5 annexin A5
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APP amyloid beta (A4) precursor protein
ARL2 ADP-ribosylation factor-like 2
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ARRB1 arrestin, beta 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATPIF1 ATPase inhibitory factor 1
AVP arginine vasopressin
AZIN1 antizyme inhibitor 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BIRC8 baculoviral IAP repeat containing 8
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
C5 complement component 5
CABIN1 calcineurin binding protein 1
CABP1 calcium binding protein 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CARD16 caspase recruitment domain family, member 16
CARD17 caspase recruitment domain family, member 17
CARD18 caspase recruitment domain family, member 18
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAST calpastatin
CCAR2 cell cycle and apoptosis regulator 2
CD109 CD109 molecule
CD27 CD27 molecule
CD46 CD46 molecule, complement regulatory protein
CDC42SE1 CDC42 small effector 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHP1 calcineurin-like EF-hand protein 1
CIB1 calcium and integrin binding 1 (calmyrin)
CISH cytokine inducible SH2-containing protein
COL28A1 collagen, type XXVIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL6A3 collagen, type VI, alpha 3
COL7A1 collagen, type VII, alpha 1
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CPEB2 cytoplasmic polyadenylation element binding protein 2
CRB2 crumbs family member 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSN2 casein beta
CST1 cystatin SN
CST11 cystatin 11
CST2 cystatin SA
CST3 cystatin C
CST4 cystatin S
CST5 cystatin D
CST6 cystatin E/M
CST7 cystatin F (leukocystatin)
CST8 cystatin 8 (cystatin-related epididymal specific)
CST9 cystatin 9 (testatin)
CST9L cystatin 9-like
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CSTL1 cystatin-like 1
DGKI diacylglycerol kinase, iota
DGKZ diacylglycerol kinase, zeta
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPEP1 dipeptidase 1 (renal)
DUS2 dihydrouridine synthase 2
DUSP19 dual specificity phosphatase 19
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ENSA endosulfine alpha
FAF2 Fas associated factor family member 2
FETUB fetuin B
FGFR1OP FGFR1 oncogene partner
FURIN furin (paired basic amino acid cleaving enzyme)
GAS6 growth arrest-specific 6
GCHFR GTP cyclohydrolase I feedback regulator
GCKR glucokinase (hexokinase 4) regulator
GLMN glomulin, FKBP associated protein
GMFB glia maturation factor, beta
GMFG glia maturation factor, gamma
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC3 glypican 3
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
H2AFY H2A histone family, member Y
HEXIM1 hexamethylene bis-acetamide inducible 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HMSD histocompatibility (minor) serpin domain containing
HRG histidine-rich glycoprotein
HSPB1 heat shock 27kDa protein 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HYAL2 hyaluronoglucosaminidase 2
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
IPO5 importin 5
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
KAT2B K(lysine) acetyltransferase 2B
KNG1 kininogen 1
LCN1 lipocalin 1
LEF1 lymphoid enhancer-binding factor 1
LMTK2 lemur tyrosine kinase 2
LRP6 low density lipoprotein receptor-related protein 6
LRRK2 leucine-rich repeat kinase 2
LXN latexin
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBIP MAP3K12 binding inhibitory protein 1
MT3 metallothionein 3
NAIP NLR family, apoptosis inhibitory protein
NCK1 NCK adaptor protein 1
NGF nerve growth factor (beta polypeptide)
NLRC4 NLR family, CARD domain containing 4
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
OAZ1 ornithine decarboxylase antizyme 1
OAZ2 ornithine decarboxylase antizyme 2
OAZ3 ornithine decarboxylase antizyme 3
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDC phosducin
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDZD3 PDZ domain containing 3
PEBP1 phosphatidylethanolamine binding protein 1
PHACTR1 phosphatase and actin regulator 1
PHACTR2 phosphatase and actin regulator 2
PHACTR3 phosphatase and actin regulator 3
PI15 peptidase inhibitor 15
PI16 peptidase inhibitor 16
PI3 peptidase inhibitor 3, skin-derived
PIF1 PIF1 5'-to-3' DNA helicase
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLN phospholamban
POT1 protection of telomeres 1
PPME1 protein phosphatase methylesterase 1
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP1R27 protein phosphatase 1, regulatory subunit 27
PPP1R35 protein phosphatase 1, regulatory subunit 35
PPP1R36 protein phosphatase 1, regulatory subunit 36
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PROL1 proline rich, lacrimal 1
PROS1 protein S (alpha)
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTN pleiotrophin
PTTG1 pituitary tumor-transforming 1
R3HDML R3H domain containing-like
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RENBP renin binding protein
RHOH ras homolog family member H
RNH1 ribonuclease/angiogenin inhibitor 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RTKN rhotekin
SAG S-antigen; retina and pineal gland (arrestin)
SCG5 secretogranin V
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SET SET nuclear proto-oncogene
SFN stratifin
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3RF2 SH3 domain containing ring finger 2
SKI SKI proto-oncogene
SLIT2 slit homolog 2 (Drosophila)
SLN sarcolipin
SLPI secretory leukocyte peptidase inhibitor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOCS7 suppressor of cytokine signaling 7
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPINK9 serine peptidase inhibitor, Kazal type 9
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SPINT4 serine peptidase inhibitor, Kunitz type 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPP2 secreted phosphoprotein 2, 24kDa
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
SSPO SCO-spondin
TAOK3 TAO kinase 3
TESC tescalcin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNK2 tyrosine kinase, non-receptor, 2
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TXNIP thioredoxin interacting protein
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UCN urocortin
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UMODL1 uromodulin-like 1
URI1 URI1, prefoldin-like chaperone
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VIL1 villin 1
WDTC1 WD and tetratricopeptide repeats 1
WFDC1 WAP four-disulfide core domain 1
WFDC10A WAP four-disulfide core domain 10A
WFDC10B WAP four-disulfide core domain 10B
WFDC12 WAP four-disulfide core domain 12
WFDC13 WAP four-disulfide core domain 13
WFDC2 WAP four-disulfide core domain 2
WFDC3 WAP four-disulfide core domain 3
WFDC5 WAP four-disulfide core domain 5
WFDC8 WAP four-disulfide core domain 8
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WNK1 WNK lysine deficient protein kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma