enilconazole-5113 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the enilconazole-5113 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADGRB1 adhesion G protein-coupled receptor B1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BBC3 BCL2 binding component 3
BRSK2 BR serine/threonine kinase 2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C22ORF46 chromosome 22 open reading frame 46
C9ORF9 chromosome 9 open reading frame 9
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CDC14A cell division cycle 14A
CEMIP cell migration inducing protein, hyaluronan binding
CLCN6 chloride channel, voltage-sensitive 6
CLDN17 claudin 17
COL11A2 collagen, type XI, alpha 2
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CTF1 cardiotrophin 1
DAGLA diacylglycerol lipase, alpha
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCX doublecortin
DRD2 dopamine receptor D2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXOSC2 exosome component 2
FGF1 fibroblast growth factor 1 (acidic)
FOXO4 forkhead box O4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPC3 glypican 3
GRB7 growth factor receptor-bound protein 7
HIC2 hypermethylated in cancer 2
HIPK3 homeodomain interacting protein kinase 3
HLF hepatic leukemia factor
HNF1A HNF1 homeobox A
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL17RB interleukin 17 receptor B
IL1RL1 interleukin 1 receptor-like 1
INO80D INO80 complex subunit D
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA1456 KIAA1456
KLF3 Kruppel-like factor 3 (basic)
LTC4S leukotriene C4 synthase
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP7D3 MAP7 domain containing 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MGAM maltase-glucoamylase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOBP myelin-associated oligodendrocyte basic protein
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTCP1 mature T-cell proliferation 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NNMT nicotinamide N-methyltransferase
NRN1 neuritin 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PARVA parvin, alpha
PCDHGA10 protocadherin gamma subfamily A, 10
PDGFB platelet-derived growth factor beta polypeptide
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLXNA2 plexin A2
POLH polymerase (DNA directed), eta
PRB1 proline-rich protein BstNI subfamily 1
PVR poliovirus receptor
PVT1 Pvt1 oncogene (non-protein coding)
RABGAP1 RAB GTPase activating protein 1
RNF122 ring finger protein 122
RUNX1-IT1 RUNX1 intronic transcript 1
SAP30 Sin3A-associated protein, 30kDa
SATB2 SATB homeobox 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOGA1 suppressor of glucose, autophagy associated 1
STK24 serine/threonine kinase 24
TBKBP1 TBK1 binding protein 1
TMEM63A transmembrane protein 63A
TOM1 target of myb1 (chicken)
TRH thyrotropin-releasing hormone
TSSK2 testis-specific serine kinase 2
TTC30A tetratricopeptide repeat domain 30A
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
ZNF44 zinc finger protein 44
ZNF76 zinc finger protein 76
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BEND5 BEN domain containing 5
BEX4 brain expressed, X-linked 4
BTC betacellulin
C10ORF88 chromosome 10 open reading frame 88
C1ORF159 chromosome 1 open reading frame 159
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASZ1 castor zinc finger 1
CCNA1 cyclin A1
CENPC centromere protein C
CENPO centromere protein O
CFAP45 cilia and flagella associated protein 45
CLDN15 claudin 15
CLDN8 claudin 8
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORO2A coronin, actin binding protein, 2A
CREB5 cAMP responsive element binding protein 5
CXORF56 chromosome X open reading frame 56
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EDIL3 EGF-like repeats and discoidin I-like domains 3
F2R coagulation factor II (thrombin) receptor
FBXL4 F-box and leucine-rich repeat protein 4
FBXL7 F-box and leucine-rich repeat protein 7
FGF13 fibroblast growth factor 13
FURIN furin (paired basic amino acid cleaving enzyme)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL7R interleukin 7 receptor
ISYNA1 inositol-3-phosphate synthase 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0319L KIAA0319-like
KIAA1462 KIAA1462
KLK6 kallikrein-related peptidase 6
KRT86 keratin 86, type II
LIFR leukemia inhibitory factor receptor alpha
LIN7B lin-7 homolog B (C. elegans)
LRRK1 leucine-rich repeat kinase 1
MAST3 microtubule associated serine/threonine kinase 3
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MTA2 metastasis associated 1 family, member 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OLFML3 olfactomedin-like 3
ORC1 origin recognition complex, subunit 1
PAIP2B poly(A) binding protein interacting protein 2B
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARM1 prostate androgen-regulated mucin-like protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRKG2 protein kinase, cGMP-dependent, type II
PSKH1 protein serine kinase H1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBL1 retinoblastoma-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SCEL sciellin
SCIN scinderin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SKI SKI proto-oncogene
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMAD7 SMAD family member 7
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEX40 testis expressed 40
TH tyrosine hydroxylase
TMEM184C transmembrane protein 184C
TMEM209 transmembrane protein 209
TMEM8B transmembrane protein 8B
TTBK2 tau tubulin kinase 2
USP6 ubiquitin specific peptidase 6
WDR18 WD repeat domain 18
WDR37 WD repeat domain 37
ZBTB3 zinc finger and BTB domain containing 3
ZNF141 zinc finger protein 141
ZNF286A zinc finger protein 286A
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446
ZNF671 zinc finger protein 671
ZNF675 zinc finger protein 675
ZNF702P zinc finger protein 702, pseudogene
ZNF74 zinc finger protein 74
ZNF816 zinc finger protein 816
ZW10 zw10 kinetochore protein