endosome Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A membrane-bounded organelle to which materials ingested by endocytosis are delivered. (Gene Ontology, GO_0005768)
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111 genes co-occuring with the biological term endosome in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ADRB2 adrenoceptor beta 2, surface
ALMS1 Alstrom syndrome protein 1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ALS2CL ALS2 C-terminal like
ANXA2 annexin A2
ANXA8 annexin A8
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APP amyloid beta (A4) precursor protein
ARF6 ADP-ribosylation factor 6
ARL1 ADP-ribosylation factor-like 1
BACE1 beta-site APP-cleaving enzyme 1
CCDC88A coiled-coil domain containing 88A
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLN5 ceroid-lipofuscinosis, neuronal 5
COPA coatomer protein complex, subunit alpha
CTSB cathepsin B
CTSL cathepsin L
CTSS cathepsin S
CXCR4 chemokine (C-X-C motif) receptor 4
DCTN1 dynactin 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA1 defensin, alpha 1
DEFA5 defensin, alpha 5, Paneth cell-specific
EEA1 early endosome antigen 1
EGFR epidermal growth factor receptor
EHD3 EH-domain containing 3
EHD4 EH-domain containing 4
EPS15 epidermal growth factor receptor pathway substrate 15
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GOLGA1 golgin A1
GPBAR1 G protein-coupled bile acid receptor 1
HDAC6 histone deacetylase 6
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IFNA1 interferon, alpha 1
IL6 interleukin 6
IST1 increased sodium tolerance 1 homolog (yeast)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAPK14 mitogen-activated protein kinase 14
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MTMR2 myotubularin related protein 2
MYO5B myosin VB
NOTCH1 notch 1
NPC1 Niemann-Pick disease, type C1
OCRL oculocerebrorenal syndrome of Lowe
OPRL1 opiate receptor-like 1
OSBPL1A oxysterol binding protein-like 1A
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PDX1 pancreatic and duodenal homeobox 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PMEPA1 prostate transmembrane protein, androgen induced 1
PRDX3 peroxiredoxin 3
PRKCG protein kinase C, gamma
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB11A RAB11A, member RAS oncogene family
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB1A RAB1A, member RAS oncogene family
RAB22A RAB22A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB7B RAB7B, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RBSN rabenosyn, RAB effector
RGS4 regulator of G-protein signaling 4
RILP Rab interacting lysosomal protein
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SCAMP3 secretory carrier membrane protein 3
SCN5A sodium channel, voltage gated, type V alpha subunit
SH3GLB1 SH3-domain GRB2-like endophilin B1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX1 sorting nexin 1
SNX10 sorting nexin 10
SNX2 sorting nexin 2
SNX3 sorting nexin 3
SNX4 sorting nexin 4
SPAST spastin
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAMBP STAM binding protein
TBC1D10A TBC1 domain family, member 10A
TBXA2R thromboxane A2 receptor
TFRC transferrin receptor
TICAM2 toll-like receptor adaptor molecule 2
TLR3 toll-like receptor 3
TOM1 target of myb1 (chicken)
TSG101 tumor susceptibility 101
USP8 ubiquitin specific peptidase 8
VCP valosin containing protein
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)