endosome membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The lipid bilayer surrounding an endosome. (Gene Ontology, GO_0010008)
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Genes

355 proteins co-occuring with the endosome membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.54598
CHMP4A charged multivesicular body protein 4A 2.34562
TSG101 tumor susceptibility 101 2.30657
CHMP4B charged multivesicular body protein 4B 2.20371
CHMP6 charged multivesicular body protein 6 1.97982
CHMP3 charged multivesicular body protein 3 1.89593
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 1.85319
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 1.75916
CHMP2B charged multivesicular body protein 2B 1.67811
CHMP5 charged multivesicular body protein 5 1.67568
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 1.67204
CHMP2A charged multivesicular body protein 2A 1.64135
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 1.58507
VTA1 vesicle (multivesicular body) trafficking 1 1.57932
CHMP1A charged multivesicular body protein 1A 1.49493
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 1.40858
SNF8 SNF8, ESCRT-II complex subunit 1.37962
EEA1 early endosome antigen 1 1.37685
CHMP4C charged multivesicular body protein 4C 1.30228
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 1.30121
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.29103
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.15467
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.12909
STAMBP STAM binding protein 1.10103
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 1.08476
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 1.07106
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.06498
TF transferrin 1.05337
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 1.0104
DNAH8 dynein, axonemal, heavy chain 8 0.975166
UBAP1 ubiquitin associated protein 1 0.963588
TFRC transferrin receptor 0.959268
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.94876
EGFR epidermal growth factor receptor 0.945907
TICAM1 toll-like receptor adaptor molecule 1 0.917644
MITD1 MIT, microtubule interacting and transport, domain containing 1 0.915309
CAPN7 calpain 7 0.912045
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.911113
SNX2 sorting nexin 2 0.899962
CEP55 centrosomal protein 55kDa 0.892093
CHMP7 charged multivesicular body protein 7 0.879173
SNX1 sorting nexin 1 0.867206
AHRR aryl-hydrocarbon receptor repressor 0.857555
ARF6 ADP-ribosylation factor 6 0.831384
PHF20 PHD finger protein 20 0.809817
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.808441
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.802021
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.788275
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.777755
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.759978
EFNA5 ephrin-A5 0.749546
SPAST spastin 0.729284
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.725705
ARF1 ADP-ribosylation factor 1 0.719906
STARD3NL STARD3 N-terminal like 0.715014
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.702626
ANXA7 annexin A7 0.699983
USP8 ubiquitin specific peptidase 8 0.699103
LAMP1 lysosomal-associated membrane protein 1 0.697784
NPC1 Niemann-Pick disease, type C1 0.695587
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.692516
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 0.683335
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.675499
MRAS muscle RAS oncogene homolog 0.67463
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.666827
EPS15 epidermal growth factor receptor pathway substrate 15 0.659913
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.65905
BROX BRO1 domain and CAAX motif containing 0.658188
SNX16 sorting nexin 16 0.654311
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.64958
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.641001
APLF aprataxin and PNKP like factor 0.634586
IFITM3 interferon induced transmembrane protein 3 0.632878
CC2D1B coiled-coil and C2 domain containing 1B 0.632451
TSPAN9 tetraspanin 9 0.630745
RAB15 RAB15, member RAS oncogene family 0.626057
RNF13 ring finger protein 13 0.626057
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 0.617982
VAMP3 vesicle-associated membrane protein 3 0.616285
KIAA0196 KIAA0196 0.615013
LMTK2 lemur tyrosine kinase 2 0.612048
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 0.611625
ANXA2 annexin A2 0.609509
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.608663
SCAMP3 secretory carrier membrane protein 3 0.598538
DENND1A DENN/MADD domain containing 1A 0.593072
S100A10 S100 calcium binding protein A10 0.590973
TLR3 toll-like receptor 3 0.587618
ARL13A ADP-ribosylation factor-like 13A 0.583012
HAS1 hyaluronan synthase 1 0.582176
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.581758
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 0.581758
REPS2 RALBP1 associated Eps domain containing 2 0.577581
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.573411
TOM1 target of myb1 (chicken) 0.571745
NSF N-ethylmaleimide-sensitive factor 0.571745
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.571329
EHD1 EH-domain containing 1 0.563847
ARRDC4 arrestin domain containing 4 0.561772
FGD6 FYVE, RhoGEF and PH domain containing 6 0.561358
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.548535
ERVW-1 endogenous retrovirus group W, member 1 0.537827
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 0.537005
RRAGC Ras-related GTP binding C 0.535361
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.530438
IGF2R insulin-like growth factor 2 receptor 0.530438
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.530028
CC2D1A coiled-coil and C2 domain containing 1A 0.523885
GLA galactosidase, alpha 0.5149
RNF126 ring finger protein 126 0.512862
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.512047
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.504724
AP1AR adaptor-related protein complex 1 associated regulatory protein 0.500258
TBC1D14 TBC1 domain family, member 14 0.491348
STX7 syntaxin 7 0.4865
ARRDC1 arrestin domain containing 1 0.484483
RAB11FIP4 RAB11 family interacting protein 4 (class II) 0.48005
FURIN furin (paired basic amino acid cleaving enzyme) 0.476831
WASH1 WAS protein family homolog 1 0.469604
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.468401
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.464397
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.462798
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.462398
ALS2CL ALS2 C-terminal like 0.458404
CD81 CD81 molecule 0.458006
RHEB Ras homolog enriched in brain 0.457606
SNX12 sorting nexin 12 0.452825
SNAP29 synaptosomal-associated protein, 29kDa 0.450836
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.450438
F11R F11 receptor 0.4425
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.442104
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.440916
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 0.439333
STX4 syntaxin 4 0.43696
RILP Rab interacting lysosomal protein 0.43617
NPC2 Niemann-Pick disease, type C2 0.434196
DDHD2 DDHD domain containing 2 0.427891
TGOLN2 trans-golgi network protein 2 0.421604
STX8 syntaxin 8 0.418468
NOTCH1 notch 1 0.416511
AP4M1 adaptor-related protein complex 4, mu 1 subunit 0.41143
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.407529
AP4B1 adaptor-related protein complex 4, beta 1 subunit 0.401693
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.397423
RAB25 RAB25, member RAS oncogene family 0.395873
SNX27 sorting nexin family member 27 0.391228
NDFIP2 Nedd4 family interacting protein 2 0.385051
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.381969
RAB34 RAB34, member RAS oncogene family 0.376586
TBC1D5 TBC1 domain family, member 5 0.37505
M6PR mannose-6-phosphate receptor (cation dependent) 0.372366
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.369684
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 0.367388
TOLLIP toll interacting protein 0.367388
IFITM2 interferon induced transmembrane protein 2 0.363185
RHPN2 rhophilin, Rho GTPase binding protein 2 0.356705
STX12 syntaxin 12 0.356324
ISG15 ISG15 ubiquitin-like modifier 0.355944
CLEC16A C-type lectin domain family 16, member A 0.355563
SNAP23 synaptosomal-associated protein, 23kDa 0.351382
OCIAD1 OCIA domain containing 1 0.349863
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.349863
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.349484
OSBP oxysterol binding protein 0.349105
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.34645
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.341529
PLEK pleckstrin 0.340395
MTMR4 myotubularin related protein 4 0.338128
LDLR low density lipoprotein receptor 0.335487
STX6 syntaxin 6 0.333602
PTDSS2 phosphatidylserine synthase 2 0.333602
ZFYVE16 zinc finger, FYVE domain containing 16 0.330589
RAB35 RAB35, member RAS oncogene family 0.329837
SNX31 sorting nexin 31 0.329084
VAMP8 vesicle-associated membrane protein 8 0.328708
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.324951
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.324576
CPLX2 complexin 2 0.319702
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.318205
WASH7P WAS protein family homolog 7 pseudogene 0.316334
WASH6P WAS protein family homolog 6 pseudogene 0.312971
CDKN2A cyclin-dependent kinase inhibitor 2A 0.312971
DDHD1 DDHD domain containing 1 0.309986
FUZ fuzzy planar cell polarity protein 0.309613
PARK2 parkin RBR E3 ubiquitin protein ligase 0.30924
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 0.307004
SH3GL2 SH3-domain GRB2-like 2 0.305515
TMEM106B transmembrane protein 106B 0.303655
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.301425
MCOLN1 mucolipin 1 0.298084
PXK PX domain containing serine/threonine kinase 0.295489
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.294007
ARF3 ADP-ribosylation factor 3 0.292897
IRF3 interferon regulatory factor 3 0.292527
WDR83 WD repeat domain 83 0.292157
SNX15 sorting nexin 15 0.292157
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.292157
SNX8 sorting nexin 8 0.290678
TOM1L2 target of myb1-like 2 (chicken) 0.290678
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.289199
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.284032
CTSD cathepsin D 0.282926
CYTH1 cytohesin 1 0.27998
TRAPPC10 trafficking protein particle complex 10 0.277038
RUFY1 RUN and FYVE domain containing 1 0.276304
MRC1 mannose receptor, C type 1 0.275569
IRGM immunity-related GTPase family, M 0.274835
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.274468
SBF2 SET binding factor 2 0.273
STARD3 StAR-related lipid transfer (START) domain containing 3 0.270434
MNT MAX network transcriptional repressor 0.270068
RAB5A RAB5A, member RAS oncogene family 0.264581
FIGN fidgetin 0.264581
RNF115 ring finger protein 115 0.262025
PI3 peptidase inhibitor 3, skin-derived 0.260931
ATP11A ATPase, class VI, type 11A 0.256561
ELL elongation factor RNA polymerase II 0.253653
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.253291
TLR9 toll-like receptor 9 0.251839
NDFIP1 Nedd4 family interacting protein 1 0.251476
HLA-B major histocompatibility complex, class I, B 0.251476
ZC3H12D zinc finger CCCH-type containing 12D 0.247854
STEAP3 STEAP family member 3, metalloreductase 0.245323
IFITM1 interferon induced transmembrane protein 1 0.243879
ANGPTL7 angiopoietin-like 7 0.242797
RNF11 ring finger protein 11 0.239916
ANXA8 annexin A8 0.239557
COPE coatomer protein complex, subunit epsilon 0.238478
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.233459
RTN2 reticulon 2 0.232029
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.231672
MFSD8 major facilitator superfamily domain containing 8 0.231315
NSG1 neuron specific gene family member 1 0.229176
ZFYVE26 zinc finger, FYVE domain containing 26 0.228819
RRAGB Ras-related GTP binding B 0.225622
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 0.224204
SNX3 sorting nexin 3 0.22279
KIF16B kinesin family member 16B 0.220321
FA2H fatty acid 2-hydroxylase 0.219265
TOM1L1 target of myb1 (chicken)-like 1 0.215063
GJC2 gap junction protein, gamma 2, 47kDa 0.215063
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.214017
CD4 CD4 molecule 0.210203
F8A2 coagulation factor VIII-associated 2 0.208137
F8A1 coagulation factor VIII-associated 1 0.208137
VIPR2 vasoactive intestinal peptide receptor 2 0.207451
NLE1 notchless homolog 1 (Drosophila) 0.207108
KIF13A kinesin family member 13A 0.206082
REEP1 receptor accessory protein 1 0.200328
LAMP2 lysosomal-associated membrane protein 2 0.196339
NISCH nischarin 0.195353
RIN1 Ras and Rab interactor 1 0.194371
SH3KBP1 SH3-domain kinase binding protein 1 0.193394
RAB1B RAB1B, member RAS oncogene family 0.190175
GYPC glycophorin C (Gerbich blood group) 0.18859
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.187646
CD63 CD63 molecule 0.18702
PDCD6IP programmed cell death 6 interacting protein 0.186708
EHD4 EH-domain containing 4 0.18516
USF2 upstream transcription factor 2, c-fos interacting 0.182723
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.182723
TLR8 toll-like receptor 8 0.179459
HRAS Harvey rat sarcoma viral oncogene homolog 0.179167
RBMS2 RNA binding motif, single stranded interacting protein 2 0.179167
CD274 CD274 molecule 0.178011
GPR143 G protein-coupled receptor 143 0.176024
PLIN3 perilipin 3 0.175745
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.175466
PLD1 phospholipase D1, phosphatidylcholine-specific 0.173543
MADD MAP-kinase activating death domain 0.172735
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.172468
NANP N-acetylneuraminic acid phosphatase 0.171673
ITGB5 integrin, beta 5 0.171673
ISG20 interferon stimulated exonuclease gene 20kDa 0.170629
STX11 syntaxin 11 0.169099
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.167125
AMPH amphiphysin 0.165231
TNIK TRAF2 and NCK interacting kinase 0.164315
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.164089
RAB5B RAB5B, member RAS oncogene family 0.161068
RAB28 RAB28, member RAS oncogene family 0.160658
TLR10 toll-like receptor 10 0.160456
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.160053
FGD1 FYVE, RhoGEF and PH domain containing 1 0.159658
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.158129
TLR7 toll-like receptor 7 0.15776
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.157039
CLCN3 chloride channel, voltage-sensitive 3 0.156513
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.14146
CD164 CD164 molecule, sialomucin 0.134964
MTMR2 myotubularin related protein 2 0.134379
STXBP3 syntaxin binding protein 3 0.133957
SCAMP1 secretory carrier membrane protein 1 0.133516
SYT3 synaptotagmin III 0.133365
CDC16 cell division cycle 16 0.132613
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.132523
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.131319
POU2F3 POU class 2 homeobox 3 0.130857
PRKD3 protein kinase D3 0.130609
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.130439
SEH1L SEH1-like (S. cerevisiae) 0.129757
SH2D3A SH2 domain containing 3A 0.12964
CLINT1 clathrin interactor 1 0.129611
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.129474
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.129184
ULK1 unc-51 like autophagy activating kinase 1 0.12901
FLCN folliculin 0.128645
MYO5B myosin VB 0.128624
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.128333
EPCAM epithelial cell adhesion molecule 0.12732
GRIP1 glutamate receptor interacting protein 1 0.127031
TTPA tocopherol (alpha) transfer protein 0.126982
MUC16 mucin 16, cell surface associated 0.126982
RPTOR regulatory associated protein of MTOR, complex 1 0.126672
RALGDS ral guanine nucleotide dissociation stimulator 0.126672
SLC38A2 solute carrier family 38, member 2 0.126469
TRIM37 tripartite motif containing 37 0.126289
VASN vasorin 0.126027
TBP TATA box binding protein 0.125853
PIGR polymeric immunoglobulin receptor 0.125525
NEXN nexilin (F actin binding protein) 0.125288
DDIT4 DNA-damage-inducible transcript 4 0.124666
HAX1 HCLS1 associated protein X-1 0.124487
TPM3 tropomyosin 3 0.124366
TPPP tubulin polymerization promoting protein 0.124074
FLOT1 flotillin 1 0.123371
CALR calreticulin 0.122764
NPC1L1 NPC1-like 1 0.121037
TFEB transcription factor EB 0.120879
SYT1 synaptotagmin I 0.120044
RAB1A RAB1A, member RAS oncogene family 0.119981
PRDX2 peroxiredoxin 2 0.119746
RLBP1 retinaldehyde binding protein 1 0.119421
PFN4 profilin family, member 4 0.119312
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.119312
PFN2 profilin 2 0.118473
MUC4 mucin 4, cell surface associated 0.117512
PFN1 profilin 1 0.117389
ANXA1 annexin A1 0.116935
HM13 histocompatibility (minor) 13 0.116361
MAP2K1 mitogen-activated protein kinase kinase 1 0.114843
SEC13 SEC13 homolog (S. cerevisiae) 0.114786
F2 coagulation factor II (thrombin) 0.113869
GFER growth factor, augmenter of liver regeneration 0.11275
MMD monocyte to macrophage differentiation-associated 0.111769
SCARB2 scavenger receptor class B, member 2 0.109961
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.109707
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.109449
STK11 serine/threonine kinase 11 0.10904
MGAM maltase-glucoamylase 0.108701
FLT3 fms-related tyrosine kinase 3 0.108317
AXIN1 axin 1 0.108317
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.108317
COL18A1 collagen, type XVIII, alpha 1 0.106933
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.10636