endoplasmic reticulum unfolded protein response Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. (Gene Ontology, GO_0030968)
External Link http://amigo.geneontology.org/amigo/term/GO:0030968
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Genes

91 genes participating in the endoplasmic reticulum unfolded protein response biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ACADVL acyl-CoA dehydrogenase, very long chain
ADD1 adducin 1 (alpha)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
BHLHA15 basic helix-loop-helix family, member a15
CALR calreticulin
CASP12 caspase 12 (gene/pseudogene)
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CREB3L3 cAMP responsive element binding protein 3-like 3
CREB3L4 cAMP responsive element binding protein 3-like 4
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTH cystathionine gamma-lyase
CUL7 cullin 7
CXCL8 chemokine (C-X-C motif) ligand 8
CXXC1 CXXC finger protein 1
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DERL1 derlin 1
DERL2 derlin 2
DERL3 derlin 3
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ERN1 endoplasmic reticulum to nucleus signaling 1
ERO1L ERO1-like (S. cerevisiae)
EXTL3 exostosin-like glycosyltransferase 3
FKBP14 FK506 binding protein 14, 22 kDa
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GOSR2 golgi SNAP receptor complex member 2
GSK3A glycogen synthase kinase 3 alpha
HDGF hepatoma-derived growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
IFNG interferon, gamma
IGFBP1 insulin-like growth factor binding protein 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLHDC3 kelch domain containing 3
LMNA lamin A/C
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MYDGF myeloid-derived growth factor
NFE2L2 nuclear factor, erythroid 2-like 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PDIA5 protein disulfide isomerase family A, member 5
PDIA6 protein disulfide isomerase family A, member 6
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PREB prolactin regulatory element binding
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RNF121 ring finger protein 121
RNF175 ring finger protein 175
SEC31A SEC31 homolog A (S. cerevisiae)
SERP1 stress-associated endoplasmic reticulum protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
SSR1 signal sequence receptor, alpha
STC2 stanniocalcin 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TATDN2 TatD DNase domain containing 2
TBL2 transducin (beta)-like 2
TLN1 talin 1
TPP1 tripeptidyl peptidase I
TSPYL2 TSPY-like 2
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCP valosin containing protein
VIMP VCP-interacting membrane selenoprotein
WFS1 Wolfram syndrome 1 (wolframin)
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YOD1 YOD1 deubiquitinase
ZBTB17 zinc finger and BTB domain containing 17