endoplasmic reticulum lumen Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The volume enclosed by the membranes of the endoplasmic reticulum. (Gene Ontology, GO_0005788)
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Genes

194 proteins co-occuring with the endoplasmic reticulum lumen cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ERN1 endoplasmic reticulum to nucleus signaling 1 1.45421
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.41306
CALR calreticulin 1.41082
CANX calnexin 1.27824
ATF6 activating transcription factor 6 1.22828
P4HB prolyl 4-hydroxylase, beta polypeptide 1.22153
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.18748
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.17311
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.13778
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.11276
XBP1 X-box binding protein 1 1.06144
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.02331
HSPA4 heat shock 70kDa protein 4 0.974198
HLA-B major histocompatibility complex, class I, B 0.970331
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.968884
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.957352
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.944482
STIM1 stromal interaction molecule 1 0.932187
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.90089
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.89672
APOB apolipoprotein B 0.886089
TMEM241 transmembrane protein 241 0.879633
DERL1 derlin 1 0.863988
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.857095
MTTP microsomal triglyceride transfer protein 0.840564
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.811652
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.811652
KRTCAP2 keratinocyte associated protein 2 0.809817
SCAP SREBF chaperone 0.807524
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.785529
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.765893
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.754076
SMR3B submaxillary gland androgen regulated protein 3B 0.748189
G6PC glucose-6-phosphatase, catalytic subunit 0.742769
SEC63 SEC63 homolog (S. cerevisiae) 0.736014
CASQ2 calsequestrin 2 (cardiac muscle) 0.731076
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 0.720797
RPN1 ribophorin I 0.71768
TMEM8A transmembrane protein 8A 0.71457
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.709693
OPCML opioid binding protein/cell adhesion molecule-like 0.707039
TOR1AIP2 torsin A interacting protein 2 0.698223
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.695148
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.683771
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.677238
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.676803
SEC62 SEC62 homolog (S. cerevisiae) 0.665529
TMX4 thioredoxin-related transmembrane protein 4 0.65259
CRELD1 cysteine-rich with EGF-like domains 1 0.647862
CES1 carboxylesterase 1 0.646145
SLC37A3 solute carrier family 37, member 3 0.645287
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 0.641429
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 0.641001
NTM neurotrimin 0.618406
COLGALT1 collagen beta(1-O)galactosyltransferase 1 0.572578
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.567585
DNAH8 dynein, axonemal, heavy chain 8 0.555145
SAMD8 sterile alpha motif domain containing 8 0.553905
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 0.553491
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.552664
SEPHS1 selenophosphate synthetase 1 0.550599
TFF3 trefoil factor 3 (intestinal) 0.550599
CREB3L1 cAMP responsive element binding protein 3-like 1 0.54936
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 0.542352
TFF1 trefoil factor 1 0.538649
RPN2 ribophorin II 0.538238
ATL3 atlastin GTPase 3 0.534951
ORAI1 ORAI calcium release-activated calcium modulator 1 0.526341
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.524294
ERP44 endoplasmic reticulum protein 44 0.523476
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 0.518165
MT4 metallothionein 4 0.517756
ARV1 ARV1 homolog (S. cerevisiae) 0.517348
MOGS mannosyl-oligosaccharide glucosidase 0.505537
TFF2 trefoil factor 2 0.503099
DDIT3 DNA-damage-inducible transcript 3 0.499042
PDIA3 protein disulfide isomerase family A, member 3 0.49418
FITM2 fat storage-inducing transmembrane protein 2 0.484483
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.481661
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.480453
TMX1 thioredoxin-related transmembrane protein 1 0.477636
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 0.474822
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.471609
DERL3 derlin 3 0.468802
STIM2 stromal interaction molecule 2 0.461599
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 0.458404
TUSC3 tumor suppressor candidate 3 0.454816
FKBP7 FK506 binding protein 7 0.45004
RTN4 reticulon 4 0.442104
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.441708
AADAC arylacetamide deacetylase 0.435775
RESP18 regulated endocrine-specific protein 18 0.432224
TRDN triadin 0.430647
TSPAN16 tetraspanin 16 0.429859
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.429465
DGAT2 diacylglycerol O-acyltransferase 2 0.429072
ATF4 activating transcription factor 4 0.427104
G6PC3 glucose 6 phosphatase, catalytic, 3 0.425138
RYR1 ryanodine receptor 1 (skeletal) 0.423567
MBOAT4 membrane bound O-acyltransferase domain containing 4 0.423174
SEP15 15 kDa selenoprotein 0.41221
SOAT1 sterol O-acyltransferase 1 0.398975
MANF mesencephalic astrocyte-derived neurotrophic factor 0.397423
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.394323
SEC11A SEC11 homolog A (S. cerevisiae) 0.392775
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.381584
SLC38A4 solute carrier family 38, member 4 0.378507
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.373899
CES2 carboxylesterase 2 0.368536
FAM155B family with sequence similarity 155, member B 0.366623
FAF2 Fas associated factor family member 2 0.361277
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.359371
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.357847
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.357467
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.356705
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.356705
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.351382
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 0.351382
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.349484
POMT2 protein-O-mannosyltransferase 2 0.347967
LMF1 lipase maturation factor 1 0.345314
CIB3 calcium and integrin binding family member 3 0.342664
ASPH aspartate beta-hydroxylase 0.338128
G6PC2 glucose-6-phosphatase, catalytic, 2 0.324576
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.324201
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 0.324201
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.323825
ZYX zyxin 0.316708
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.316708
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.314839
SIL1 SIL1 nucleotide exchange factor 0.314091
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.313718
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.310732
NFE2L1 nuclear factor, erythroid 2-like 1 0.304771
EHF ets homologous factor 0.302168
BVES blood vessel epicardial substance 0.301425
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.298826
AQP1 aquaporin 1 (Colton blood group) 0.294748
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.293267
PACS2 phosphofurin acidic cluster sorting protein 2 0.291787
MGAT4C MGAT4 family, member C 0.291047
HYOU1 hypoxia up-regulated 1 0.289569
MCFD2 multiple coagulation factor deficiency 2 0.279245
ERLIN2 ER lipid raft associated 2 0.261296
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.259837
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.258745
VCP valosin containing protein 0.258381
RTN4R reticulon 4 receptor 0.258016
DOLK dolichol kinase 0.25438
HLA-C major histocompatibility complex, class I, C 0.253291
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.252564
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.251114
ATP13A1 ATPase type 13A1 0.239916
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.239197
CREB3L4 cAMP responsive element binding protein 3-like 4 0.236683
TOR1A torsin family 1, member A (torsin A) 0.231672
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.225267
PRNP prion protein 0.224913
SEC23A Sec23 homolog A (S. cerevisiae) 0.22173
ERLEC1 endoplasmic reticulum lectin 1 0.221378
CREB3L3 cAMP responsive element binding protein 3-like 3 0.213669
TRAC T cell receptor alpha constant 0.211933
MIER1 mesoderm induction early response 1, transcriptional regulator 0.211933
KIF5B kinesin family member 5B 0.210894
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.206423
INS insulin 0.201335
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.195681
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.19307
ERO1L ERO1-like (S. cerevisiae) 0.189539
LUM lumican 0.18859
MPDU1 mannose-P-dolichol utilization defect 1 0.187333
PEMT phosphatidylethanolamine N-methyltransferase 0.18516
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 0.183935
CIDEC cell death-inducing DFFA-like effector c 0.180339
TXN thioredoxin 0.178877
SOX1 SRY (sex determining region Y)-box 1 0.175188
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.174635
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.174361
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.172468
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.170888
CKAP4 cytoskeleton-associated protein 4 0.167125
SEC23B Sec23 homolog B (S. cerevisiae) 0.166643
ARSH arylsulfatase family, member H 0.165463
COL4A2 collagen, type IV, alpha 2 0.16477
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.162763
SDF4 stromal cell derived factor 4 0.160658
CHMP2B charged multivesicular body protein 2B 0.160658
CALU calumenin 0.159268
BIK BCL2-interacting killer (apoptosis-inducing) 0.159074
SALL1 spalt-like transcription factor 1 0.158692
PLIN2 perilipin 2 0.157218
SLN sarcolipin 0.140665
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.139014
MUC2 mucin 2, oligomeric mucus/gel-forming 0.137605