endocrine gland cancer Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system. (Human Disease Ontology, DOID_170)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:170
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Genes

105 genes associated with the disease endocrine gland cancer in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.03069
FUT2 fucosyltransferase 2 (secretor status included) 2.78774
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.35824
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 1.72628
COL18A1 collagen, type XVIII, alpha 1 1.35281
FAM3B family with sequence similarity 3, member B 1.33384
RASIP1 Ras interacting protein 1 1.25141
AFP alpha-fetoprotein 1.16893
FOXE1 forkhead box E1 0.949327
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.871531
DBP D site of albumin promoter (albumin D-box) binding protein 0.829859
SEC1P secretory blood group 1, pseudogene 0.815638
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.742156
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.676602
RPL18 ribosomal protein L18 0.620974
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.615501
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 0.562203
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 0.553014
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.553014
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.534605
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.516381
DIRC3 disrupted in renal carcinoma 3 0.506358
NRG1 neuregulin 1 0.487532
IL17F interleukin 17F 0.470241
MAP1A microtubule-associated protein 1A 0.468444
CA11 carbonic anhydrase XI 0.467401
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.466731
TP53BP1 tumor protein p53 binding protein 1 0.465532
SBF2 SET binding factor 2 0.457729
BICD1 bicaudal D homolog 1 (Drosophila) 0.452375
CLPTM1L CLPTM1-like 0.450303
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.444585
DAPK1 death-associated protein kinase 1 0.438494
PRB2 proline-rich protein BstNI subfamily 2 0.438494
DEC1 deleted in esophageal cancer 1 0.430311
GRID1 glutamate receptor, ionotropic, delta 1 0.425585
RNF149 ring finger protein 149 0.422054
LPIN2 lipin 2 0.4172
MYO1D myosin ID 0.417062
BCAR1 breast cancer anti-estrogen resistance 1 0.415651
SMTN smoothelin 0.415126
PARK2 parkin RBR E3 ubiquitin protein ligase 0.414949
DGKH diacylglycerol kinase, eta 0.413595
DCP1B decapping mRNA 1B 0.413127
RNF43 ring finger protein 43 0.413127
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.412857
HNF1A HNF1 homeobox A 0.412207
PVT1 Pvt1 oncogene (non-protein coding) 0.412049
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.411526
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.410865
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.407083
ERO1LB ERO1-like beta (S. cerevisiae) 0.406834
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.392766
WWOX WW domain containing oxidoreductase 0.39208
ANKRD12 ankyrin repeat domain 12 0.391637
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.39142
SUGCT succinyl-CoA:glutarate-CoA transferase 0.389631
IMPG2 interphotoreceptor matrix proteoglycan 2 0.388236
SGMS1 sphingomyelin synthase 1 0.387197
FAM149A family with sequence similarity 149, member A 0.387072
SYNDIG1 synapse differentiation inducing 1 0.386579
RUNX2 runt-related transcription factor 2 0.385944
SIM1 single-minded family bHLH transcription factor 1 0.385828
MGST2 microsomal glutathione S-transferase 2 0.385636
ASTN2 astrotactin 2 0.384292
POC1B POC1 centriolar protein B 0.382818
NXPH1 neurexophilin 1 0.382423
L3MBTL4 l(3)mbt-like 4 (Drosophila) 0.380791
EMILIN2 elastin microfibril interfacer 2 0.380565
AVEN apoptosis, caspase activation inhibitor 0.379964
KIAA1217 KIAA1217 0.379113
HNF4G hepatocyte nuclear factor 4, gamma 0.375934
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.375564
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.374939
CAB39L calcium binding protein 39-like 0.374473
UBASH3B ubiquitin associated and SH3 domain containing B 0.374041
TP63 tumor protein p63 0.373423
EML6 echinoderm microtubule associated protein like 6 0.373401
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.372554
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.372145
FNBP1L formin binding protein 1-like 0.371608
SMOC1 SPARC related modular calcium binding 1 0.370951
LPAR1 lysophosphatidic acid receptor 1 0.370891
CARD9 caspase recruitment domain family, member 9 0.368877
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.368176
ZNF831 zinc finger protein 831 0.367172
APTX aprataxin 0.365018
TMEM213 transmembrane protein 213 0.36473
CTIF CBP80/20-dependent translation initiation factor 0.364446
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0.363486
PRKCA protein kinase C, alpha 0.363486
ATP13A4 ATPase type 13A4 0.361946
MEF2BNB MEF2B neighbor 0.360987
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.357876
IGSF21 immunoglobin superfamily, member 21 0.357293
SLC22A18 solute carrier family 22, member 18 0.357293
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.348723
IQSEC1 IQ motif and Sec7 domain 1 0.348723
DSCAM Down syndrome cell adhesion molecule 0.348723
NRG3 neuregulin 3 0.348723
DFNB31 deafness, autosomal recessive 31 0.337413
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.337413
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.329388
LIN7C lin-7 homolog C (C. elegans) 0.326244
TMOD1 tropomodulin 1 0.325953