elongin complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (abut 100 kDa)and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa)subunits. (Gene Ontology, GO_0070449)
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Genes

79 proteins co-occuring with the elongin complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CUL5 cullin 5 2.43003
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 2.42667
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 2.40257
CUL2 cullin 2 2.28299
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 2.20669
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.13331
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.99191
CISH cytokine inducible SH2-containing protein 1.57989
PARK2 parkin RBR E3 ubiquitin protein ligase 1.41586
ELL elongation factor RNA polymerase II 1.40634
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2) 1.21894
LRRC41 leucine rich repeat containing 41 1.19931
VBP1 von Hippel-Lindau binding protein 1 1.16799
SKP1 S-phase kinase-associated protein 1 1.10256
ASB6 ankyrin repeat and SOCS box containing 6 1.01784
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 1.00794
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 0.978559
SOCS3 suppressor of cytokine signaling 3 0.968401
SOCS6 suppressor of cytokine signaling 6 0.957831
WSB1 WD repeat and SOCS box containing 1 0.945907
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3) 0.931716
FBXO40 F-box protein 40 0.929363
ASB1 ankyrin repeat and SOCS box containing 1 0.879173
MED26 mediator complex subunit 26 0.843318
SOCS2 suppressor of cytokine signaling 2 0.815322
COMMD1 copper metabolism (Murr1) domain containing 1 0.772275
CDC34 cell division cycle 34 0.766804
SOCS1 suppressor of cytokine signaling 1 0.761342
ASB9 ankyrin repeat and SOCS box containing 9 0.749546
SOCS4 suppressor of cytokine signaling 4 0.725258
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.693832
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.67463
CUL1 cullin 1 0.637578
JAK2 Janus kinase 2 0.617557
ANK1 ankyrin 1, erythrocytic 0.599802
HOXB3 homeobox B3 0.582176
ASB2 ankyrin repeat and SOCS box containing 2 0.563017
PRAME preferentially expressed antigen in melanoma 0.551838
GTF2B general transcription factor IIB 0.540706
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D 0.532078
SOCS5 suppressor of cytokine signaling 5 0.516532
UBE2M ubiquitin-conjugating enzyme E2M 0.503099
RNF31 ring finger protein 31 0.488115
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.485693
LIG4 ligase IV, DNA, ATP-dependent 0.478038
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.45641
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.449643
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 0.440916
TP53 tumor protein p53 0.438146
IRS4 insulin receptor substrate 4 0.403637
CUL7 cullin 7 0.399363
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.391615
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.391228
UBE2H ubiquitin-conjugating enzyme E2H 0.387751
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.383509
TRIM32 tripartite motif containing 32 0.373516
DDB1 damage-specific DNA binding protein 1, 127kDa 0.368153
MED23 mediator complex subunit 23 0.364331
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.317456
EPAS1 endothelial PAS domain protein 1 0.312597
UBE2K ubiquitin-conjugating enzyme E2K 0.311851
IRS2 insulin receptor substrate 2 0.305143
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.295119
UBE2S ubiquitin-conjugating enzyme E2S 0.290308
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.279612
PCGF2 polycomb group ring finger 2 0.260566
TBP TATA box binding protein 0.252927
JAK1 Janus kinase 1 0.252564
SGPL1 sphingosine-1-phosphate lyase 1 0.232744
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.232029
LOXL1 lysyl oxidase-like 1 0.210894
TALDO1 transaldolase 1 0.208137
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.202009
RPN1 ribophorin I 0.196339
CUL4A cullin 4A 0.194698
FLNB filamin B, beta 0.167125
TRIM5 tripartite motif containing 5 0.166884
SFN stratifin 0.158129
RRM1 ribonucleotide reductase M1 0.156342