elevated level of mitotic sister chromatid exchange Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased number of crossovers between sister chromatids during mitosis resulting in increased numbers of reciprocal exchanges of DNA between the two chromosomes; normally crossover exchanges are supressed during mitosis and only occur in meiosis (Mammalian Phenotype Ontology, MP_0003701)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003701
Similar Terms
Downloads & Tools

Genes

7 gene mutations causing the elevated level of mitotic sister chromatid exchange phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FANCM Fanconi anemia, complementation group M
LIG3 ligase III, DNA, ATP-dependent
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
RECQL RecQ helicase-like
RECQL5 RecQ protein-like 5
RGPD1 RANBP2-like and GRIP domain containing 1