earlystage Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

180 genes co-occuring with the biological term earlystage in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
ALB albumin
APAF1 apoptotic peptidase activating factor 1
APLN apelin
APOA1 apolipoprotein A-I
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ATG5 autophagy related 5
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCL7A B-cell CLL/lymphoma 7A
BCRP1 breakpoint cluster region pseudogene 1
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CA9 carbonic anhydrase IX
CCL7 chemokine (C-C motif) ligand 7
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD44 CD44 molecule (Indian blood group)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CISD2 CDGSH iron sulfur domain 2
CIZ1 CDKN1A interacting zinc finger protein 1
CKAP2 cytoskeleton associated protein 2
CLDN1 claudin 1
CLDN4 claudin 4
CLDN7 claudin 7
CLU clusterin
COMP cartilage oligomeric matrix protein
CRY1 cryptochrome circadian clock 1
CSF1 colony stimulating factor 1 (macrophage)
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR4 chemokine (C-X-C motif) receptor 4
DIABLO diablo, IAP-binding mitochondrial protein
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DMRT1 doublesex and mab-3 related transcription factor 1
E2F3 E2F transcription factor 3
EGFR epidermal growth factor receptor
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FOXM1 forkhead box M1
GATA4 GATA binding protein 4
HBA1 hemoglobin, alpha 1
HECA headcase homolog (Drosophila)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HOXB13 homeobox B13
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL17A interleukin 17A
IL17RB interleukin 17 receptor B
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLK4 kallikrein-related peptidase 4
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LEP leptin
LRRK2 leucine-rich repeat kinase 2
MACC1 metastasis associated in colon cancer 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAPT microtubule-associated protein tau
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR1254-1 microRNA 1254-1
MIR142 microRNA 142
MIR149 microRNA 149
MIR196A1 microRNA 196a-1
MIR34B microRNA 34b
MIR374A microRNA 374a
MIR574 microRNA 574
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MSLN mesothelin
MTA1 metastasis associated 1
MUC1 mucin 1, cell surface associated
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
NEFL neurofilament, light polypeptide
NELL1 NEL-like 1 (chicken)
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
NUPR1 nuclear protein, transcriptional regulator, 1
OCLN occludin
PARK7 parkinson protein 7
PC pyruvate carboxylase
PDPK1 3-phosphoinositide dependent protein kinase 1
PEBP1 phosphatidylethanolamine binding protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PON1 paraoxonase 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PROM1 prominin 1
PRSS50 protease, serine, 50
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
RGR retinal G protein coupled receptor
RHOF ras homolog family member F (in filopodia)
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFN stratifin
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SND1 staphylococcal nuclease and tudor domain containing 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX17 SRY (sex determining region Y)-box 17
SPINK1 serine peptidase inhibitor, Kazal type 1
SREBF2 sterol regulatory element binding transcription factor 2
SSX2 synovial sarcoma, X breakpoint 2
SSX3 synovial sarcoma, X breakpoint 3
SSX4 synovial sarcoma, X breakpoint 4
STOML2 stomatin (EPB72)-like 2
STX1A syntaxin 1A (brain)
TCF21 transcription factor 21
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TIMP4 TIMP metallopeptidase inhibitor 4
TJP1 tight junction protein 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TRPS1 trichorhinophalangeal syndrome I
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
ULBP2 UL16 binding protein 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBTB24 zinc finger and BTB domain containing 24