dsif complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes. (Gene Ontology, GO_0032044)
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36 proteins co-occuring with the dsif complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.50906
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 2.35609
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.89108
NELFA negative elongation factor complex member A 1.66538
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 1.20138
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.09543
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.851583
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.807065
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.79927
NKRF NFKB repressing factor 0.796062
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.775014
CHD1 chromodomain helicase DNA binding protein 1 0.771819
CDK9 cyclin-dependent kinase 9 0.753623
NELFB negative elongation factor complex member B 0.67463
HIST2H2BF histone cluster 2, H2bf 0.63715
HIST1H2BH histone cluster 1, H2bh 0.63715
HIST3H2BB histone cluster 3, H2bb 0.63715
HIST1H2BD histone cluster 1, H2bd 0.636723
HIST1H2BC histone cluster 1, H2bc 0.63544
HIST1H2BF histone cluster 1, H2bf 0.63544
HIST1H2BA histone cluster 1, H2ba 0.634159
JAG2 jagged 2 0.584268
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.553491
H3F3B H3 histone, family 3B (H3.3B) 0.549773
H3F3A H3 histone, family 3A 0.549773
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.529618
SSRP1 structure specific recognition protein 1 0.525931
LMO2 LIM domain only 2 (rhombotin-like 1) 0.47844
CDK7 cyclin-dependent kinase 7 0.340017
SETD2 SET domain containing 2 0.335487
SRRM1 serine/arginine repetitive matrix 1 0.33511
GATA2 GATA binding protein 2 0.297713
USF1 upstream transcription factor 1 0.294378
NELFCD negative elongation factor complex member C/D 0.268969
AICDA activation-induced cytidine deaminase 0.236324
CCNT1 cyclin T1 0.167125