dopamine-491 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dopamine-491 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAM22 ADAM metallopeptidase domain 22
ADD2 adducin 2 (beta)
AGXT alanine-glyoxylate aminotransferase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANK2 ankyrin 2, neuronal
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG12 autophagy related 12
BCL2L14 BCL2-like 14 (apoptosis facilitator)
CAV3 caveolin 3
CCDC22 coiled-coil domain containing 22
CCPG1 cell cycle progression 1
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLASP2 cytoplasmic linker associated protein 2
CLCN5 chloride channel, voltage-sensitive 5
CLUAP1 clusterin associated protein 1
CREM cAMP responsive element modulator
CTNND1 catenin (cadherin-associated protein), delta 1
DCHS1 dachsous cadherin-related 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPS8L3 EPS8-like 3
FAM76A family with sequence similarity 76, member A
FH fumarate hydratase
FKBPL FK506 binding protein like
GMIP GEM interacting protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
HMOX1 heme oxygenase 1
HRASLS2 HRAS-like suppressor 2
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0141 KIAA0141
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT7 keratin 7, type II
LINC00339 long intergenic non-protein coding RNA 339
MATK megakaryocyte-associated tyrosine kinase
MRPL35 mitochondrial ribosomal protein L35
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTMR3 myotubularin related protein 3
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NEK1 NIMA-related kinase 1
NELL2 NEL-like 2 (chicken)
NNAT neuronatin
OBSL1 obscurin-like 1
OVOL1 ovo-like zinc finger 1
PCP4 Purkinje cell protein 4
PDCD1 programmed cell death 1
PDE4B phosphodiesterase 4B, cAMP-specific
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PRKD3 protein kinase D3
PSG6 pregnancy specific beta-1-glycoprotein 6
PTN pleiotrophin
RPL10 ribosomal protein L10
RPS2 ribosomal protein S2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
S100A9 S100 calcium binding protein A9
SAFB2 scaffold attachment factor B2
SEZ6L seizure related 6 homolog (mouse)-like
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC17A4 solute carrier family 17, member 4
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STARD5 StAR-related lipid transfer (START) domain containing 5
STMN1 stathmin 1
STX2 syntaxin 2
TAZ tafazzin
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TGM2 transglutaminase 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNS1 tensin 1
TPT1 tumor protein, translationally-controlled 1
TSPAN15 tetraspanin 15
TSPAN32 tetraspanin 32
UBE4B ubiquitination factor E4B
UBL3 ubiquitin-like 3
USP2 ubiquitin specific peptidase 2
WAS Wiskott-Aldrich syndrome
WDR18 WD repeat domain 18
WISP1 WNT1 inducible signaling pathway protein 1
ZFR zinc finger RNA binding protein
ZNF589 zinc finger protein 589
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACIN1 apoptotic chromatin condensation inducer 1
ACTN4 actinin, alpha 4
ADAMTSL4 ADAMTS-like 4
AGMAT agmatine ureohydrolase (agmatinase)
ALAS1 5'-aminolevulinate synthase 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALX3 ALX homeobox 3
APOLD1 apolipoprotein L domain containing 1
ARHGAP5 Rho GTPase activating protein 5
ASCC1 activating signal cointegrator 1 complex subunit 1
BIK BCL2-interacting killer (apoptosis-inducing)
C16ORF59 chromosome 16 open reading frame 59
CAMKV CaM kinase-like vesicle-associated
CARD8 caspase recruitment domain family, member 8
CCDC170 coiled-coil domain containing 170
CCP110 centriolar coiled coil protein 110kDa
CDC37 cell division cycle 37
CEP192 centrosomal protein 192kDa
CHN1 chimerin 1
CHRM4 cholinergic receptor, muscarinic 4
CIDEC cell death-inducing DFFA-like effector c
CLCN2 chloride channel, voltage-sensitive 2
CNTD2 cyclin N-terminal domain containing 2
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
DENND4C DENN/MADD domain containing 4C
DLK2 delta-like 2 homolog (Drosophila)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP22 dual specificity phosphatase 22
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPPK1 epiplakin 1
ERCC4 excision repair cross-complementation group 4
EVPL envoplakin
FAM188A family with sequence similarity 188, member A
FANCF Fanconi anemia, complementation group F
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FOXO1 forkhead box O1
FSD1 fibronectin type III and SPRY domain containing 1
GALR3 galanin receptor 3
GOLM1 golgi membrane protein 1
GPATCH2L G patch domain containing 2-like
GUSBP3 glucuronidase, beta pseudogene 3
HAND1 heart and neural crest derivatives expressed 1
HHIPL2 HHIP-like 2
HIST1H1C histone cluster 1, H1c
HIST1H3G histone cluster 1, H3g
IDO1 indoleamine 2,3-dioxygenase 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JMJD4 jumonji domain containing 4
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT5 keratin 5, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LOC440895 two pore channel 3 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MON1B MON1 secretory trafficking family member B
NHEJ1 nonhomologous end-joining factor 1
NXF2 nuclear RNA export factor 2
OR2C1 olfactory receptor, family 2, subfamily C, member 1
PCDHB6 protocadherin beta 6
PHOX2B paired-like homeobox 2b
PLIN3 perilipin 3
POMT2 protein-O-mannosyltransferase 2
PPA1 pyrophosphatase (inorganic) 1
PPP1R26 protein phosphatase 1, regulatory subunit 26
PROZ protein Z, vitamin K-dependent plasma glycoprotein
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SAG S-antigen; retina and pineal gland (arrestin)
SDC3 syndecan 3
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD1A SET domain containing 1A
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI2 snail family zinc finger 2
SNUPN snurportin 1
SNX6 sorting nexin 6
SPRR1B small proline-rich protein 1B
SRRD SRR1 domain containing
SUN2 Sad1 and UNC84 domain containing 2
TMEM176A transmembrane protein 176A
TMSB4Y thymosin beta 4, Y-linked
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53BP1 tumor protein p53 binding protein 1
TPST2 tyrosylprotein sulfotransferase 2
TSPAN1 tetraspanin 1
WDR13 WD repeat domain 13
ZFP36 ZFP36 ring finger protein
ZNF134 zinc finger protein 134
ZNF180 zinc finger protein 180
ZNF33B zinc finger protein 33B
ZNRF4 zinc and ring finger 4