dna damage checkpoint Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds. (Gene Ontology, GO_0000077)
External Link http://amigo.geneontology.org/amigo/term/GO:0000077
Similar Terms
Downloads & Tools

Genes

77 genes participating in the dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ATF2 activating transcription factor 2
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BABAM1 BRISC and BRCA1 A complex member 1
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRSK1 BR serine/threonine kinase 1
C10ORF90 chromosome 10 open reading frame 90
CCNA2 cyclin A2
CCND1 cyclin D1
CCNG1 cyclin G1
CDC14B cell division cycle 14B
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CEP63 centrosomal protein 63kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CLOCK clock circadian regulator
CLSPN claspin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F1 E2F transcription factor 1
FAM175A family with sequence similarity 175, member A
FBXO31 F-box protein 31
FBXO6 F-box protein 6
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GIGYF2 GRB10 interacting GYF protein 2
H2AFX H2A histone family, member X
HINFP histone H4 transcription factor
HMGA2 high mobility group AT-hook 2
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
IER3 immediate early response 3
INTS7 integrator complex subunit 7
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBD4 methyl-CpG binding domain protein 4
MDC1 mediator of DNA-damage checkpoint 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
NBN nibrin
NEK11 NIMA-related kinase 11
NEK6 NIMA-related kinase 6
PEA15 phosphoprotein enriched in astrocytes 15
PLK1 polo-like kinase 1
PLK5 polo-like kinase 5
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RAD9B RAD9 homolog B (S. pombe)
RBBP8 retinoblastoma binding protein 8
RFWD3 ring finger and WD repeat domain 3
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RPA2 replication protein A2, 32kDa
RPA4 replication protein A4, 30kDa
RPS27L ribosomal protein S27-like
SYF2 SYF2 pre-mRNA-splicing factor
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TIPIN TIMELESS interacting protein
TIPRL TOR signaling pathway regulator
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
WAC WW domain containing adaptor with coiled-coil
XPC xeroderma pigmentosum, complementation group C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF830 zinc finger protein 830